14
votes
1answer
2k views

Evolutionarily, why do male rats and horses lack nipples?

Developmentally male rats don't have nipples because (reddit) Testosterone release in the fetal male rat happens before the stage of mammogenesis where the teat is formed whereas other species ...
8
votes
2answers
2k views

How to find miRNA binding sites on a specific gene?

I am trying to find miRNAs that bind to the 3'UTR of a specific gene. What is the best way of doing that (that is, with a good scoring analysis that is most commonly used by researchers in this area)? ...
4
votes
3answers
383 views

Could a sperm be altered to contain a female's genetics?

while discussing with a friend a while back on the likelihood a Funtari (a woman with both fully developed and functioning sets of genitalia) existing in real life we got into a discussion of weather ...
3
votes
1answer
183 views

Are people genetically predisposed to being interested in specific fields/ideas? How does specialization occur?

I'm not sure if I formulated my question well, but I'm curious about a couple statements made by Steven Pinker and and James Heckman. In this interview: http://www.youtube.com/watch?v=KJ9Ad6s8g7I&...
1
vote
2answers
688 views

Real time PCR standard curve

As blunt as possible: when performing real time PCR it is a routine step to run one PCR in order to plot a "standard curve" with several decreasing dilution ratios from your sample. what is the real ...
79
votes
4answers
63k views

Why is uracil used in RNA rather than thymine?

What is the advantage gained by the substitution of thymine with uracil? I have read previously that it is due to thymine being "better protected" and therefore more suited to the storage role of DNA,...
56
votes
4answers
49k views

Death because of distilled water consumption

One of my friends said that I would die if I drank distilled water (we were using it in a chemistry experiment) I gave it a go and surprisingly did not die. I did a bit of Googling and found this ...
24
votes
4answers
2k views

How and where, in the human brain, are memories stored?

Background I am a computer programmer who is fascinated by artificial intelligence and artificial neural networks, and I am becoming more curious about how biological neural networks work. Context &...
23
votes
3answers
3k views

Which organism has the smallest genome length?

Which animal/plant/anything has smallest length genome?
5
votes
3answers
851 views

A free book/resource for learning genetics?

I took an undergrad class in genetics. I felt it was not too intensive and I do not feel prepared for grad school (if I can manage to get in.) Does anyone know of a preferably free resource for ...
14
votes
2answers
622 views

Evolution in 37 years, is it possible?

I am confused, can evolution ( speciation ) really occur in such a short time ? In 1971, biologists moved five adult pairs of Italian wall lizards from their home island of Pod Kopiste, in the ...
34
votes
1answer
1k views

What is itching?

What exactly at the molecular level is itching? What physiological function does itching serve, if any? I cant remember the reference but a PLCb3 null mice lost the itch phenotype, so presumably it is ...
18
votes
6answers
3k views

Why would a single celled organism evolve to be multi-celled?

I read a story this week on Richard Lenski who has been 'evolving' E. coli for more than 50,000 generations now. One comment I read was from someone who doesn't accept Evolution who pointed out that ...
9
votes
2answers
478 views

Why do we have more male infant born?

For every 104 male babies,we have 100 female babies and there is a Statistics which is more reliable (we have 997 female infant born per 1000 male infant born). what's the reason? why do we have male ...
9
votes
3answers
9k views

Why doesn't recombination occur in male Drosophila?

"Males do not show meiotic recombination, facilitating genetic studies." For a while I have known that this phenomenon occurs, this quote comes from the Wikipedia page on Drosophila melanogaster, ...
6
votes
1answer
1k views

What gives things their colour?

My 6 year old daughter asked me 2 biology-related questions yesterday and I tried my best to answer them with the aid of YouTube videos. One of the questions (I may post the other one too) was ...
0
votes
3answers
1k views

How does the modern theory of evolution solve these apparent problems? [closed]

I hold to the truth of Evolution, but I've encountered several problems with it, that I can't answer, and I can't find an answer for, despite much research. If would be great if anyone can answer ...
23
votes
2answers
1k views

Why is menstruation in wild animals not a disadvantage to organismal survival?

When I watch wilderness specials for more than a few minutes, I notice a familiar pattern: predators are depicted as being alerted by the scent of blood. Wounded animals seem to make the best prey and ...
21
votes
2answers
25k views

What is the difference between local and global sequence alignments?

There are a bunch of different alignment tools out there, and I don't want to get bogged down in the maths behind them as this not only between softwares, but varies from software version to version. ...
13
votes
3answers
477 views

How does a person get AIDS?

I am inquisitive to know about how a person contracts AIDS. Among the common masses it's still the belief that having sex with multiple partners causes the disease but that is not the case when read ...
9
votes
2answers
7k views

Why is saltatory conduction faster than continuous conduction?

How does spacing apart sodium and potassium channels allow the action potential to travel faster down the axon? This is the reason always cited for saltatory conduction and myelination, but my mental ...
8
votes
1answer
182 views

Why must a planet be in a star's “habitable zone” to have life?

I have seen many articles that talk about a star's "habitable zone" as the ring around it which is just the right temperature for planets to have liquid water, which is necessary for life. My question ...
8
votes
3answers
1k views

Is there any kind of immortality in plants?

I asked a question about immortality of hydra and learned good things about senescence. Now I would like to know about immortality in plants, if there is some kind of immortality in plants and how ...
5
votes
1answer
618 views

How do sharks and other fish conserve and gain water in marine environments?

With the osmolarity of the average vertebrate being around 300mOsml, and salt water having an osmolarity of 1000mOsml, why does the water from the shark not leave to the salt water around it? I ...
4
votes
1answer
309 views

How significant is the genetic component of homosexual behaviour?

From some basic googling, I found that nobody has ever proven that people are born gay and that environment plays a great part in homosexuality. I wish to know if there is a genetic component to ...
2
votes
1answer
1k views

What is the relationship between UV wavelength and penetration depth into human skin?

Some background - Some recent research has strongly suggested that UVA penetration into the skin is far more dangerous than UVB, a very good example is this paper by Agar et al. (2004). My query is, ...
15
votes
2answers
305 views

Are some animals, like dogs and cats, color-blind and how do we know that?

I have heard that some animals, including dogs, cats and donkeys, are color-blind. They cannot recognize any color. Is that true? And how can humans verify that animals are color-blind, or not? During ...
14
votes
2answers
506 views

Have we ever observed two drosophila lineages that evolved reproductive isolation in labs?

Background The standard definition of species refers to the concept of reproductive isolation. If two lineages are found to be reproductively isolated, then we consider these two lineages to belong ...
10
votes
1answer
247 views

Seeing strange things in light

I have noticed that if you look directly at tubelight (I have only white ones in my home) and close your eyes little, you see little random shaped colourless things sometimes with slow speed and ...
9
votes
2answers
47k views

What is the function of the RNA primer in DNA replication?

During DNA replication, RNA primase puts an RNA primer in the lagging strand. What is the function of this RNA primer? Why can't the enzymes put DNA fragments directly?
8
votes
4answers
2k views

Does darker skin color make it easier to live under sun?

I have always thought darker colors absorb more heat from the sun, so if you are wearing a white T-shirt you will be cooler under sun than wearing a darker T-shirt, or a black piece of steel will be ...
7
votes
1answer
180 views

How do tea, coffee, and beer dehydrate you?

For the long time I am trying to find out if the following is truth: They say that some beverages dehydrates. I heard that about tea (sometimes green, sometimes black, sometimes both), coffee, beer ...
5
votes
1answer
429 views

Do any birds beside the family Columbidae (or any reptile or mammal) feed their young “Crop Milk”

Birds from the family Columbidae (e.g., doves and pigeons) produce a fatty, milk-like substance in their crop. The secretion is often referred to as "crop milk." They feed crop milk to their young ...
5
votes
1answer
80 views

Evolution of dominance of alleles

Can someone tell me where can I find detailed text about mechanisms of evolution of dominance? Or, if it is possible, I would be grateful if someone will tell me about them here.
5
votes
2answers
295 views

Real time PCR normalization algorithm

When performing normalization of real time PCR results, I found two ways of doing it: In my lab they follow the next layout: $\text{Efficiency}^{-(CT\ _{\large\text{interest gene}} - CT _{\large\...
4
votes
3answers
265 views

What is the state-of-the-art algorithm for multiple sequence alignment?

Which algorithm or algorithms are considered the standard or state-of-the-art for multiple sequence alignment? How big is the need for better algorithms? How many sequences need to be alignment in a ...
3
votes
2answers
232 views

Is better healthcare a bane to the long-term survival of the human race?

The theory of natural selection has it that individuals with better genes tend to survive and reproduce, passing their genes to their offspring. This gradual process results in a population more ...
3
votes
1answer
3k views

What is the standing genetic variation?

I am reading this review. In the first part, the author introduces Standing Genetic Variation, described as: STANDING GENETIC VARIATION Allelic variation that is currently segregating within a ...
2
votes
1answer
5k views

Why do different humans look different?

Although farmers appear to be able to tell their cows apart, cows look very much alike to me. And this similarity in appearance seems to be a general trait across the animal kingdom: one individual of ...
1
vote
2answers
387 views

How does the size of insert affects the rate of Homologous Recombination in yeast?

When performing genetic knockouts in yeast using homologous recombination to replace a target gene sequence via a vector DNA, does the region between the flanking regions in the vector have to be the ...
183
votes
3answers
96k views

Why do I only breathe out of one nostril?

I was just sitting with my hand next to my nose and I realized that air was only coming out of the right nostril. Why is that? I would think I would use both, it seems much more efficient. Have I ...
68
votes
3answers
4k views

Why did the process of sleep evolve in many animals? What is its evolutionary advantage?

The process of sleep seems to be very disadvantageous to an organism as it is extremely vulnerable to predation for several hours at a time. Why is sleep necessary in so many animals? What advantage ...
50
votes
4answers
4k views

Why are there no wheeled animals?

In physics, "almost everything is already discovered, and all that remains is to fill a few unimportant holes." (See Jolly.) Therefore, on Physics SE, people are veering off into different directions: ...
26
votes
7answers
10k views

How do we know that humans and chimpanzees evolved from a common ape ancestor? [closed]

Richard Dawkins in one of his videos says that Evolution is a fact and not just a theory. He goes on to say that man and chimpanzees both evolve from apes. Is this correct (Is evolution a fact and ...
39
votes
3answers
2k views

Can scientists create totally synthetic life?

This particular question has been of a great deal of interest to me, especially since it dives at the heart of abiogenesis.
13
votes
3answers
1k views

Mathematical Modelling of Natural Selection

I'm a math undergrad looking for some papers on modelling the process of natural selection. The only paper I've been able to find is by the pre-eminent mathematician Herbert Wilf from 2010, There's ...
41
votes
3answers
4k views

Why does cracking a joint make noise?

What causes the noise when you crack a joint? Is joint cracking harmful?
13
votes
7answers
6k views

How did the first self replicating organism come into existence?

When people try to explain evolution, they tell me that evolution is a cumulative result of mutations & natural section of the more superior individuals of a particular species. I think I'm fairly ...
35
votes
4answers
7k views

Why would a plant evolve to produce an addictive chemical?

It seems kind of anti-productive in terms of survival for a plant to produce an addictive chemical as that plant will constantly be sought after by animals that ingest it. In this instance, I'm ...
34
votes
4answers
820 views

Why are amino acids in biology homochiral?

Why are nearly all amino acids in organisms left-handed (exception is glycine which has no isomer) when abiotic samples typical have an even mix of left- and right-handed molecules?

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