All Questions

7
votes
2answers
51 views

How to find miRNA binding sites on a specific gene?

I am trying to find miRNAs that bind to the 3'UTR of a specific gene. What is the best way of doing that (that is, with a good scoring analysis that is most commonly used by researchers in this area)? ...
0
votes
1answer
21 views

Recovery from a more severe injury can be shorter than from a less severe one [on hold]

I vaguely remember reading somewhere that in certain cases, recovery from a more severe injury can occur faster than from a less severe injury. This was motivated by claiming that the less severe ...
0
votes
0answers
20 views

Is it possible to simulate the effects of high altitudes for plants?

Note- I considered asking this on gardening.stackexchange.com but i believe it is better suited for this site since it deals with more complicated material. As I understand it, certain plants ...
6
votes
3answers
260 views

Why does replication require primers while transcription does not?

In transcription, there is no need for any primer. I guess the basic mechanism of DNA polymerase & RNA polymerase is the same. So why does replication have the need for a primer?
1
vote
0answers
31 views

pedigree analysis calculation of the probabilty of 1 child having phenylketonuria out of 4 children [on hold]

In a family flows an autosomal recessive phenyketonuria trait.consider a couple with unknown genotype.Their grandparents are heterozygous carriers for sure and the parents of the couple have unknown ...
-2
votes
0answers
36 views

Eadie-Hofstee Plot [on hold]

If an eadie-hofstee plot shows two distinct gradient, Does this imply cooperativity between the two active sites? and how do we find the hill coefficient? The question asked us to plot graphs of V ...
-1
votes
0answers
30 views

Is autocatalysis a non-Michaelis-Menten Reaction [on hold]

If a reaction involves its own product altering the rate of reaction and the affinity to the substrate, does it still obey the Michaelis-Menten kinetic model?
3
votes
2answers
12k views

What does 5' and 3' mean in DNA and RNA strands?

What are 5' and 3' in DNA and RNA strands? Please clarify with some images and please use simple English.
0
votes
1answer
35 views

Epitope annotated protein

What is epitope annotted protein?? The book from which I got this term is : http://www.springer.com/biomed/immunology/book/978-1-4939-1114-1
1
vote
0answers
26 views

What is the difference between rheobase and threshold?

What is the difference between rheobase and threshold? In the definitions I've read it's described as almost the same thing like it says the threshold is Stimulus whose strength (or voltage) is ...
2
votes
0answers
28 views

Does sociality evolved before or after the ability of motility?

According to book Life Ascending: The Ten Great Inventions o Evolution. (Lane, N.;2010), Motility has indeed transformed life on earth in ways that are not immediately apparent, from the ...
1
vote
1answer
31 views

How do the quantities of ATP formed during aerobic and anaerobic respiration compare? [on hold]

How do the quantities of ATP formed during aerobic and anaerobic respiration compare?
1
vote
0answers
45 views

Is the attached digital camera on the top have the same magnification than visible in eyepiece? [migrated]

There are some microscopes with digital camera system attached to the top. But does it include or bypass eyepiece magnification? E.g. 40x objective lens and 10x eyepiece making the total ...
4
votes
1answer
48 views

Redundancy of the genetic code

One particular codon codes only for one amino acid, but an amino acid can be coded for by several different codons. Now according to the genetic code, the codon UUU ...
1
vote
2answers
38 views

Why do physicians try to match HLA complexes for organ transplant?

My understanding of acute transplant rejection is that donor dendritic cells present donor antigens on MHC1 to host naive CD8+ T-cells resulting in an immune response against the graft. If you match ...
4
votes
2answers
37 views

Does trypsin strip flask coating?

Mammalian cell/tissue cultures sometimes require flasks coated with proteins. My uneducated guess is that these proteins mimic the ECM, perhaps the basal lamina, so finicky contact-dependent cells can ...
1
vote
1answer
36 views

Identify the pink mold infecting refrigerated lemons

I made lemon juice 6 month ago. I just washed the lemon using brush and then cut them into pieces. Then I put one layer of lemon in the bottle followed by one layer of sugar Again one layer of lemon ...
1
vote
3answers
37 views

Can connections between neurons be weakened?

Connections between neurons are said (by Wikipedia) to be strengthened as part of learning - can they also be weakened (below the original level)? I understand the concept of the connections ...
1
vote
4answers
49 views

Are neural connections one-way?

I'm trying to think about how two neurons communicate, typically shown in pictures as an electric pulse traveling along a long, thin connective tissue. Is this depiction somewhat accurate, and if so, ...
9
votes
3answers
66 views

How can I label cryotubes in a way that eliminates the problem of legible hand-writing?

My lab stores biological material (tissue, cells, plasma, serum) in a -130 C, liquid nitrogen freezer. The cryotubes that we use to store a samples are labelled by hand which frequently creates ...
0
votes
2answers
75 views

What is called the condition where no pacemaker cells are active in heart for short-time?

Assume that the heart is beating but no pacemaker cells is working for at least 15 seconds. This would be very long compensatory pause if extrasystole started it. There may be some low frequent ...
0
votes
1answer
18 views

Explain the mode of inheritance and determine genotypes [closed]

Please help me with the following question. I am really struggle with it. Every time you cross male and female flies with star eyes and dichaete wings, you observe a phenotypic ratio of 4 star, ...
4
votes
1answer
647 views

Why Do Nerve Signals Get Crossed?

First off, I don't know if this is a normal healthy thing to occur. There have been many times where I have an itch on say my arm and I scratch it, only to feel the scratching elsewhere on my body. I ...
2
votes
1answer
43 views

What is happening physically when I get sleepy and when I wake up?

After a week of too little sleep, I slept about 12 hours last night to "catch up". It made me wonder: what is happening physically that signals that I'm done sleeping, or conversely, that I need to ...
0
votes
1answer
29 views

Earliest and latest onset of Huntington's Disease(Chorea)?

Huntington's disease can hit at any age, although it tends to hit middleaged people most often. What is the youngest and oldest person that has exhibited Huntington's? Clarification: By oldest I mean ...
0
votes
0answers
32 views

What is the color of white skin? [closed]

I know you nominally call it "white" and the color is given by: refraction of light across the spectrum (white-ish, though leaning more towards red) melanin (brown) capillary vessels (pinkish) But ...
2
votes
1answer
32 views

Sequencing a specific region of a genome

First off, I'm new to bioinformatics and I am learning about DNA sequencing. Let's say that I knew that a specific region of a genome which contained information about a disease (whether it a person ...
2
votes
1answer
27 views

DNA methylation on the forward vs reverse strand?

I'm wondering if there are meant to be differences in DNA methylation between the forward and the reverse strand of the gene? I'm wondering because in primer design for bisulfite pyrosequencing one ...
5
votes
2answers
198 views

How is it possible to even hope for an ebola epidemic of this current size to remain contained to a relatively small part of Africa?

As of 2014-09-14 at least 5347 cases of ebola have been identitied. Some estimates are much higher. While experts are sounding the alarm to try to get sufficient resources to contain the outbreak, ...
9
votes
2answers
1k views

To what extent is Ebola airborne? (aerosols)

Recently, CIDRAP at the University of Minnesota announced that Ebola may be more transmissible through aerosols than previously thought. I lack the familiarity with the field to critically evaluate ...
10
votes
2answers
1k views

How long does the Ebola virus remain infectious on contaminated items or surfaces?

I'm sure there will be variation depending on what the contaminated item or surface is made of - linens, I could imagine, would remain dangerous for longer than a door-knob. But if the items are not ...
4
votes
2answers
112 views

Is ebola non-contagious until symptoms appear? Why?

There's been a lot of talk lately about the man who recently came down with ebola in Dallas, Texas. While I live elsewhere, I keep hearing quotes from CDC and state officials that ebola is not ...
8
votes
2answers
1k views

How does the ebola virus attack?

How does the ebola virus attack and how do some people get away with it? Normally any virus would attack a cell with some kind of receptors and some kind of lock and key mechanism entering the cell ...
1
vote
1answer
18 views

What are the reactions in the body that triggers dizziness after cigar(nicotine) smoking in non-smokers?

Suppose there is a person that has never used nicotine in any form in his/her life. Why does the person get dizzy after a few "shots" from a cigar(nicotine)? What's the difference between using other ...
2
votes
1answer
31 views

The biology behind tree pruning and hedge trimming

I read two contradictory arguments which both seem logical to me, related to the tree pruning and hedge trimming: You should prune/cut trees only outside the growing season, when the tree is ...
2
votes
3answers
67 views

Is the quality of sleep dependent on sleep duration?

I've been facing this lately, where I will wake up in the middle of the night after sleeping for perhaps 2-3 hours and be wide awake, but when I go back to sleep, I wake up more tired than before. ...
8
votes
2answers
75 views

Fate of erythrocytes after splenectomy

The spleen is considered a graveyard for red blood cells. So in case of Splenectomy (complete surgical removal of the spleen), what would be the fate of red blood cells? Would this cause Polycythemia? ...
2
votes
1answer
59 views

Nature Scientific Reports vs. BMC Genomics

I do not know if this question to suitable here or not. I posted it as I think biologists can help me in this question. If not suitable here, then I am sorry for that. I have written paper which I ...
0
votes
1answer
22 views

What controls gut motility?

I have two different papers. One claims that gut motility is reduced by stimulation of the Opioid κ and δ receptors. The receptors are activated by Morphine and certain derivatives, specifically ...
0
votes
0answers
37 views

What is the effective line detected by ML II channel in ECG?

I want to find the approximate effective path/line on the heart that ML II channel detects on the heart. The normal ECG angle is 59 angle. ML II channel, which is a combination of two bipolar leads, ...
7
votes
1answer
80 views

Providing small molecules to cells on a filter plate

Lets imagine that I have mammalian cells that I've immobilized on a filter. Now I want to keep providing small molecules to these immobilized cells without resolubilizing the cells. The caveat is ...
0
votes
0answers
13 views

Gastroenteritis virus causing mutation of the Enterochromaffin cells

I am working on the solution to a worldwide problem: IBS or chronic diarrhea following a viral gastroenteritis infection. I think I have an answer. The only missing piece to the puzzle I found in a ...
-1
votes
0answers
38 views

DNA and aminoacid sequence [closed]

5’ ATG TCA ACT CGG GCA ACA CAT TGT CTG TAT GAC GAA TAA TTA ACG 3’ TAC AGT TGA GCC CGT TGT GTA ACA GAC ATA CTG CTT ATT AAT TGC Q1: What will be the resulting ...
1
vote
1answer
34 views

Please help me to identify this red worm

I found bunch of red worms coming out of sink. It is rather unusual to find an overwhelmingly large number of worms. It doesn't seem like earthworm or horsehair worm. I don't know much about the ...
2
votes
2answers
149 views

Hardy Weinberg Equilibrium after 5 Generations

1 There is a population not at HWE where red eye = $a^+$ (dominant) and white eyes = $a^-$. if $a^+/a^+ = 0.6$ $a^-/a^+ = 0.1$ $a^-/a^- = 0.3$ what are the frequencies of the $a^+$ and $a^-$ ...
2
votes
2answers
42 views

How did aquatic dinosaurs go extinct?

Dominant theory is that 'normal' dinosaurs went extinct from ether super volcano or meteor impact or combination of both. However there were aquatic dinosaurs that are not present at this day. Was it ...
0
votes
1answer
14 views

Does re polarization of muscle fibers mean that the muscle bundle is relaxed?

If I flex my bicep and continue to contract it does it mean that the muscle cells are in depolarizing state and not re polarizing?
1
vote
1answer
39 views

What are the risks of elevating the legs too regularly and when tired?

I started to to think the pathophysiology of elevating legs high next to the wall too often and when you are tired. I think possible manifestations some damage to valves of the veins (No!) because ...
8
votes
1answer
65 views

Can a human cell live indefinetely in a controlled environment?

How long can a human cell live in a controlled environment, given all necessary nutrients, temperatures, mechanisms for waste removal, and other requirements are provided for? Put differently: Can a ...
0
votes
1answer
16 views

Among xerophyte plants, which one grow faster and consume water the least?

In an effort to select for the most suitable plants to possibly colonise desert and stop its expansion, what would be the xerophyte plants that grow the faster and expand on surface, while using the ...

15 30 50 per page