All Questions

18
votes
2answers
1k views

Can rats pass on memories of a maze to their offspring?

A friend of mine told me once about a documentary movie he saw some years ago. On this movie he saw scientists talking about particular experiment. This experiment involved rats and probably ...
18
votes
3answers
782 views

How is RNAse contamination in RNA based experiments prevented?

Does anyone have any suggestions to prevent RNAse contamination when working with RNA? I tend to have issues with degradation regardless of whether I use DEPC treated / RNAse free water and filtered ...
18
votes
3answers
20k views

Why do mammalian red blood cells lack a nucleus?

How did the red blood cell in humans get to lose its nucleus (and other organelles)? Does the bone marrow just not put the nucleus in, or is it stripped out at some stage in the construction of the ...
18
votes
2answers
2k views

Do gene expression levels necessarily correspond to levels of protein activation?

I have seen a lot of research into molecular mechanisms of diseases/phenotypes use measures of RNA as a 'proxy' for the level of protein available in the cell. Is this actually valid? My problem ...
18
votes
3answers
240 views

How crowded is the bacterial cell?

I was wondering what is the protein concentration in an E. coli cell. When studying enzyme kinetics and activity in vitro, I would argue that the substrate and enzyme concentrations resemble those in ...
18
votes
2answers
325 views

Can an adult without genetic lactase persistence still develop a tolerance for dairy foods?

While investigating the rise of adult lactose tolerance, I came across the news that China has been encouraging its citizens to drink more milk, even though most of the Asian population lacks the SNP ...
4
votes
2answers
133 views

The gender of offspring of Twins?

Given identical twin males, Michael and Douglas, Douglas and his wife have four children, all of whom are girls. Michael and his wife have only one child, a boy, and are expecting another. What are ...
4
votes
3answers
67 views
+50

Why do I feel funny in my tummy when riding a virtual roller coaster?

I've ridden a virtual roller coaster on an Oculus Rift. I felt tension as I went up to the top, but more interestingly I actually felt my stomach drop when I went down the steep drop on the other ...
4
votes
1answer
39 views

Mechanisms of extracellular stimulation of neurons

When stimulating a group of neurons with an electrode, let's say we put it in a region that contains axons, what is the mechanism by which the axons are stimulated? I've been told electrodes ...
4
votes
1answer
47 views

Redundancy of the genetic code

One particular codon codes only for one amino acid, but an amino acid can be coded for by several different codons. Now according to the genetic code, the codon UUU ...
4
votes
1answer
32 views

Is viral protein expression important for peptide vaccine?

I would like to know if proteins expressed in higher quantities, such as DNA polymerase, would be better vaccine candidates for a T-cell based vaccine. Thanks, Bernardo
4
votes
1answer
241 views

Why do antidepressants have a delayed onset of action?

Why do antidepressants take so long to reach efficacy? I've read of theories about it perhaps being due to the strength of negative feedback via serotonergic and adrenergic autoreceptors during the ...
4
votes
2answers
37 views

Does trypsin strip flask coating?

Mammalian cell/tissue cultures sometimes require flasks coated with proteins. My uneducated guess is that these proteins mimic the ECM, perhaps the basal lamina, so finicky contact-dependent cells can ...
3
votes
1answer
58 views

XXY (Klinefelter's) & Trisomy 21 & X-inactivation

I read that X-inactivation doesn't tend to happen in males, but then when someone is XXY, they are a male because of the Y. However these individuals tend to live. So does that mean that ...
3
votes
1answer
50 views

Hamming distance between two DNA strings

By definition from Wikipedia, the Hamming distance between two strings of equal length is the number of positions at which the corresponding symbols are different. In other words, it is the number of ...
3
votes
2answers
1k views

NaCl role in CTAB - DNA complex in DNA extraction

I have a question about the role of NaCl in the DNA extraction process. So for NaCl concentrations under 0.5M, CTAB and DNA molecules can create complexes. In those concentrations, proteins and other ...
3
votes
1answer
21 views

Why is Cysteine and Tyrosine used to calculate a sequence isoelectric point?

Why are the amino acids - cysteine and tyrosine used in isoelectric point calculations for a protein sequence, yet neither of them are positively charged molecules? and are not used in net charge ...
3
votes
1answer
20 views

How is Microenvironment strictly defined?

I started to think this definition of Wikipedia: Microenvironment (biology), a small or relatively small usually distinctly specialized and effectively isolated biophysical environment (as of ...
3
votes
0answers
34 views

Does eating antacid (such as Magnesia) before meal have any impact on digestion?

During an anatomy lecture I heard of the importance of the acidity of gastric acid (e.g., killing microorganisms, dissolving food, being a factor for triggering further processes). If a healthy person ...
3
votes
1answer
66 views

Mechanism of Muscle Growth

According to this video (sorry for the poor reference but it represents my level of understanding in physiology), muscle grow as a consequence of repairing micro-lesions. How are these micro-lesions ...
2
votes
3answers
204 views

Where are the evolutionary “inbetweeners”? [closed]

The problem I've always had with evolution is the actual lack of variation between animals. More specifically, the lack of observable gradual change between species. Take for example the hammerhead ...
2
votes
2answers
62 views

Book recommended for neurobiology

I am looking for a good explanatory book concerning Neurobiology. I am interested on how the brain works but prior to this I believe that I have to start learning things about the biology of neurons. ...
2
votes
2answers
41 views

How did aquatic dinosaurs go extinct?

Dominant theory is that 'normal' dinosaurs went extinct from ether super volcano or meteor impact or combination of both. However there were aquatic dinosaurs that are not present at this day. Was it ...
2
votes
1answer
70 views

For how long can a raven stay airborne (a week or more)?

I'm wondering for how long a raven can stay continuously airborne, if strained to do so? If it makes a difference, I'm mostly interested in the Common raven, Corvus corax. Are there for instance any ...
2
votes
1answer
20 views

If hermaphrodite C. elegans can reproduce with females?

C. elegans can self fertilize, or they can mate with males. But are they able to mate with females? Or is there some kind of morphological barrier that prevents that?
2
votes
5answers
184 views

Does a neuron ever generate an action potential without stimuli?

Most accounts I read involving action potentials and synapses and the like tend to focus mostly on the action potential as a mere automatic reaction to another similar event happening upstream. From ...
2
votes
1answer
17 views

When writing about past research should I use the species name they employed or the modern version?

I am currently writing a literature review in which I am talking about the old research on the subject. When this research was carried out the species I'm talking about were classed under a different ...
2
votes
2answers
62 views

Why is Eadie- Hofstee Plot not linear

Besides the reason of cooperativity between multiple active sites on an enzyme, what are the other reasons for the Eadie-Hofstee plot to be non-linear
2
votes
1answer
27 views

DNA methylation on the forward vs reverse strand?

I'm wondering if there are meant to be differences in DNA methylation between the forward and the reverse strand of the gene? I'm wondering because in primer design for bisulfite pyrosequencing one ...
2
votes
1answer
27 views

Are added yogurt cultures harmful to the gut?

I have read somewhere that the live culture added to yogurt acting as "healthy" gut bacteria are actually synthetic and harmful. Any truth to this? If so, what are some alternatives to getting good ...
2
votes
1answer
34 views

What is the difference between a phosphotransferase, a phosphatase, a phosphorylase and a kinase?

I've looked in several sources, but I'm still confused. This is what I have so far: A phosphotransferase catalyzes the addition of a phosphate group. A kinase is a type of phosphotransferase that ...
2
votes
2answers
42 views

Is the Hypothalamus part of the Central Nervous System or Endocrine System

Sorry for a certainly naive question. Some references (for example https://faculty.washington.edu/chudler/nsdivide.html) seem to to indicate that the hypothalamus is part of the Central Nervous ...
2
votes
1answer
32 views

Sequencing a specific region of a genome

First off, I'm new to bioinformatics and I am learning about DNA sequencing. Let's say that I knew that a specific region of a genome which contained information about a disease (whether it a person ...
2
votes
0answers
28 views

Does sociality evolved before or after the ability of motility?

According to book Life Ascending: The Ten Great Inventions o Evolution. (Lane, N.;2010), Motility has indeed transformed life on earth in ways that are not immediately apparent, from the ...
1
vote
2answers
13 views

How can histidine be classified both as positively charged and hydrophobic?

I saw the chart in this post Histidine aromaticity. Since I'm not allowed to comment and post a question instead of an answer, I have to ask my question in a separate thread. How can histidine be ...
1
vote
0answers
11 views

Gene Therapy for Cystic Fibrosis Extension

Thank you everyone for answering my previous two questions on CF. I have decided to write a paper specifically on the use of viral vectors and gene therapy for cystic fibrosis. I was told by my ...
1
vote
0answers
12 views

what is the role of ctab in plant dna extraction [duplicate]

i get good results for dna extraction by using ctab method but i doesn't have that proper information for role/function of ctab and other chemical. Anyone know, please briefly explain ......
1
vote
0answers
19 views

C. elegans and nutrition

If there is ample amount of food, do C. elegans worms know when to stop eating or do they store extra energy? Could they put this extra energy to use by moving faster or putting more eggs?
1
vote
0answers
30 views

pedigree analysis calculation of the probabilty of 1 child having phenylketonuria out of 4 children [on hold]

In a family flows an autosomal recessive phenyketonuria trait.consider a couple with unknown genotype.Their grandparents are heterozygous carriers for sure and the parents of the couple have unknown ...
1
vote
1answer
31 views

How do the quantities of ATP formed during aerobic and anaerobic respiration compare? [on hold]

How do the quantities of ATP formed during aerobic and anaerobic respiration compare?
0
votes
2answers
55 views

What are the genus and species name of different breeds of dog?

Can you refer me to a good source containing the genus and species name of different breeds of dogs?
0
votes
1answer
30 views

What are the structual differences between DNA and RNA? [on hold]

How is the structure of DNA different from that of RNA?
0
votes
1answer
36 views

Fruit colour related to the dissolving of pectin

What does the dissolving of pectin have to do with the colour of a fruit?
0
votes
1answer
21 views

Could transfusion of a different blood type cure blood-based cancers?

Different antigen detection triggers an immune system response that could perhaps stimulate mitochondria and such in killing cancer cells - something like chemo without the hair-loss?
0
votes
1answer
41 views

What impacts penetrance of Huntington's disease?

From Principles of Life by H. Craig Heller, David E. Sadava, Mary V. Price: From what I understand, Huntington's disease exhibits varying degrees of penetrance depending on how many times the ...
0
votes
2answers
19 views

Is this a valid definition of independent assortment?

"Allelic combinations separate randomly. I.e. a parent might be Aa and Bb for two traits but that doesn't necessarily mean the gametes will strictly be AB or ab but any of a number of combinations. ...
0
votes
1answer
39 views

What is the progressive evolutionary advantage that leads to flying?

As far as I understand, all life started as non-flying and flying came about by natural selection. What is the evolutionary advantageous "path" to flying? Or is there something else to explain this?
0
votes
2answers
36 views

What are non-heritable changes to genomes?

I am told that mutations are heritable changes to the genome. So this begs the question - what are non-heritable changes to genome?
0
votes
2answers
36 views

Why do physicians try to match HLA complexes for organ transplant?

My understanding of acute transplant rejection is that donor dendritic cells present donor antigens on MHC1 to host naive CD8+ T-cells resulting in an immune response against the graft. If you match ...
0
votes
2answers
84 views

Does “Garbage Enzyme cleaner” contain cleaning enzymes?

There are many recipes which call for using fruit peel fermentation process to make a concentrated enzyme cleaner solution, some variations call to add bakers yeast. So the question arises that does ...

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