13
votes
1answer
146 views

Solubility of DNA in water

This would seem to be an easy to answer question, but I was unable to find an answer (in g/L) for generic double-stranded DNA or plasmid neither on Google nor on BioNumbers. I would expect the ...
5
votes
2answers
101 views

Non Coding DNA and its effect on evolution

I had a discussion with a friend of mine; from his understanding, bacteria and other small organisms have higher amounts of "coding" DNA and, as such, are able to evolve much faster than organisms ...
6
votes
2answers
188 views

What is the difference between sequence, reads, and contigs of genetic material?

Can someone explain the differences between sequence, reads, and contigs of genetic material such as DNA, if possible with an example? I am new to bioinformatics, and I have not found any conclusive ...
3
votes
1answer
38 views

Pavlovian Conditioning And Synesthesia

I have been reading about Pavlovian brain conditioning and it seems that documented cases are mostly limited to motor reflexes (like conditioning an eyelid to close when hearing a tone) or taste ...
8
votes
2answers
344 views

Is it possible to add a new sequence to a blast database without recreating it from scratch?

I have a new sequence and I want to add it to a pre-constructed BLAST database containing other sequences. The makeblastdb help does not give any hint on this regard.
-4
votes
0answers
45 views

Can pandas hunt for meat?

Recently, I learned that pandas have a carnivore's digestive system but that it exists almost exclusively as a herbivore. If pandas hunted would they be able to find meat in their environment? Can't ...
0
votes
1answer
67 views

What is the point at which abiogenesis is complete and evolution begins? [closed]

Is the minimum criterion for life a single cell? It seems that self-replicating RNA is not enough, but I don't know. What would be the most basic cell that could fit this criterion and what cells ...
12
votes
1answer
112 views

Doing a medical study on yourself?

What research guidelines is a person legally mandated to follow if they want to do medical experimentation on themselves? There is a large amount of variation in the types of medical experiments so I ...
4
votes
1answer
40 views

Medium for Pseudomonas?

What is a good minimal medium for Pseudomonas bacteria? Do I need different media for different Pseudomonas species?
4
votes
0answers
35 views

Does anxiety about weight or eating cause people to become overweight?

A while ago I saw this TED talk about the futility of dieting. The speaker suggests that a body maintains a homeostatic weight point and returns to that weight after dieting has stopped: Turns out ...
2
votes
0answers
36 views

Do High Iron Stores (but within the healthy range) Make Sun Exposure Damage Worse?

Ultraviolet damage from sun exposure is related to the creation of free radicals. Iron is often involved in exacerbating damage by free radicals. Having lower iron stores is associated with reduced ...
5
votes
1answer
60 views

Neuronal coordinates of C.elegans

Is there a list of neural coordinates for C.elegans? I need it to build a 3D model. Update: What is available at the moment is: full connectome for example, at openconnectome; neuron description ...
1
vote
1answer
36 views

Evolutionary advantages of wet nose of cats and dogs?

Everyone knows that some animals, at least cats and dogs, keep their noses wet and cool. But why did they evolve it? What evolutionary advantages does it provide? Smell-sensing cells need cooling for ...
-3
votes
2answers
5k views

At what stage of meiosis does “first meiotic arrest of oogenesis” occur?

An exam question asked what stage of meiosis corresponds with "first meiotic arrest of oogenesis". I can't work out the answer from the wiki page - can anyone explain which step this refers to?
2
votes
0answers
45 views

Can DNA test of my grandparent's brother reveal my heritage from that branch of the family?

I'm thinking about doing that DNA test on all my grandparents to know where their genes come from. They are getting very old and I don't want to let the opportunity pass to gather more knowledge about ...
-4
votes
0answers
20 views

pheromones and attraction [closed]

The more different the pheromones of two people, the more attracted they will be towards each other and Pheromones are related to genes. According to this, two blood related people cannot be sexually ...
-1
votes
0answers
27 views

Why would I not get a hangover anymore after losing weight? [closed]

First off, I hope this question is not off-topic. It is related to a specific question I have about my own personal experience. However, it is absolutely not a question seeking medical advice. I ...
0
votes
0answers
19 views

Control studies for vital signs [closed]

This is related to my cyborg thought experiment(which is really an extension of my cell from scratch thought experiment). It is about determining heart rate, breathing rate, temperature, %O2, and ...
14
votes
2answers
5k views

Can one die from pain?

Is it possible that a human or any other creature can die from pain? I googled and found different answers. Some articles say Yes while others say No.
1
vote
0answers
21 views

Getting read size less then specified in parameter file Flux Simulation

I have tried to use flux simulation tool to generate simulated RNA-seq data. I gave the following parameter file to flux-simulation shell script ...
3
votes
1answer
44 views

What class of histone deacetylase (HDAC) inhibitor is sodium valproate (VPA)?

VPA is a known HDAC inhibitor. But I cannot find what class it is. What class is it? And is there any method of finding an answer better than floundering with Google?
0
votes
1answer
33 views

Programmatic way to differentiate homodimers from heterodimers?

For pdb files is there a simple programmatic way to determine if the file is made up of homodimers or heterodimers. I have many files so an online tool or some ...
7
votes
2answers
111 views

Why did the Brain develop in the front in most organisms?

I was wondering: why most, well, pretty much all organism with a brain have it right in front of their bodies or at the top.
14
votes
2answers
2k views

Will humans and animals be harmed by frequencies outside their hearing range?

The human ear (for example) is sensitive to frequencies from 20Hz to 20kHz. Any sound beyond that limit would not be heard by us naturally. Will it harm us (effect our ability to hear) when we hear ...
-3
votes
0answers
48 views

Coffee efficiency? [closed]

I was thinking and I realize that people have a tolerance to caffeine right. So I stopped drinking coffee for a while and then when I started to drink again it got me all really hyped. So what I think ...
3
votes
1answer
37 views

What are the mechanistics of stinging nettles?

There is a lot of research on why nettle extracts causes skin irritation and a stinging sensation. However, I cannot find information on how the extract is injected in human skin. Similarly, I haven't ...
13
votes
3answers
5k views

Why is hydrofluoric acid so dangerous if it is a weak acid?

I've read that hydrofluoric acid (HF) is extremely dangerous to touch, but what exactly makes it so toxic? It's weak acid ($K_a = 7.2 \times 10^{–4}$) and dissociates approximately 1/1000 as much as ...
10
votes
2answers
74 views

How can we predict protein folding in silico?

Currently, there is a lot of research focused on solving the folding patterns of proteins using computers (Folding@Home, https://fold.it/portal/, etc.). The question that I have is: How do you know ...
-1
votes
0answers
32 views

What is the difference between pianka's index and renkonen index? [closed]

Why do Pianka's and renkonen indices give different results, even though they are both meant to measure overlap and similarities?
-4
votes
0answers
27 views

16S rRNA sequencing [closed]

I am currently in a M. Sci. program but I want to do a project on identifying bacteria species from waste and crude oil contaminated sites. The problem is that I don't know the protocol used in ...
-1
votes
0answers
37 views

What are comparative advantage of different NGS platforms? [closed]

Sanger and Maxam-Gilbert introduced first two methods to sequence DNA. Sanger's Method had great comparative advantages and led the sequencing projects in its time. As I know, currently we have three ...
3
votes
1answer
74 views

Any evolutionary explanation for human blood groups?

What is the explanation of people having blood types from an evolutionary perspective?
5
votes
1answer
48 views

Do any birds have established “poke a predator's eyes out” behavior?

Is there a pattern/tactics of behavior in any birds species that consists of attacking a predator's eyes with its beak? I'm looking for established tactics, not 1 or 2 anecdotal examples.
8
votes
1answer
54 views

Do ant colonies prioritize survival of particular members above others?

In some (perhaps small) human communities people may starve because they have no income. This could be interpreted as a consequence of them not participating in the community, hence they don't get any ...
4
votes
0answers
42 views

Horizontal gene transfer from humans

It is known that some viruses embed themselves in the human genome. Is there a mechanism by which human genes can be transferred to other animals or plants by means of viruses shuttling them from ...
0
votes
0answers
14 views

Is PTB ECG Diagnostic Database AAMI standard?

The PTB database can be found here. There has been only one publication about the database in the recent 15 years which list challenges in the database. You can review the ECGs (electrocardiogram) ...
-1
votes
0answers
69 views

With respect to kegg website [closed]

With respect to related R class in KEGG website: http://www.genome.jp/tools-bin/relclass?RC00064 What is the biological or statistical relevance of the score? How is it computed? And does it ...
12
votes
1answer
673 views

What portion of the electromagnetic spectrum do cats see?

I have seen numerous articles and various information about how cats and dogs see into the ultraviolet spectrum with interesting artistic renderings such as this: ...
3
votes
1answer
70 views

Why do cows (and other hooved animals) need a hierarchy?

Clearly numerous animals have a hierarchy - hereditary one. For example, I understand zebras have a pecking order, and must map this hierarchy from highest to first in line and lowest to last in line ...
6
votes
0answers
29 views

What is cross-immunoreactivity, and how does it impact vaccine development?

What I understand about cross-immunoreactivity is that the antibody induced by one specific antigen is also fairly effective against another antigen. How would this be used for vaccine development? ...
7
votes
1answer
133 views

Counterintuitive action of Vitamin D?

Vitamin D acts in a way which to me is counterintuitive. It functionally supplemets Parathormone. It in the intestinal tract steps up calcium absorption by altering nuclear gene expression and also ...
10
votes
3answers
1k views

Why deoxyribose for DNA and ribose for RNA?

Why is DNA made out of deoxyribose and RNA made of ribose? Why can't they both use ribose or deoxyribose? I think that the deoxyribose gives an advantage in storing genes, the job of DNA and ribose is ...
5
votes
1answer
58 views

Calling for Free Online Data for Paediatric ECG?

I need free online data about heart murmurs to study these: heart murmur frequency , S2 heart sound frequency and its split, murmur timing, and duration, murmur intensity, S3 sound presence and ...
2
votes
3answers
149 views

To get Standard ECG from PhysioNet?

I am trying to get standard ECG by using PhysioNet's ATM with parameters but I get It should be something like How can you get complete standard 12-lead ECG out of Physionet database?
0
votes
1answer
13 views

Any databases with AAMI ECG and ECHO?

There is no AAMI 12-lead ECG databases available online. All of them have problems. I and my friends finally finalised our tests with St Petersburg. It is not AAMI. So the next step is to search ...
3
votes
1answer
47 views

How did the endoplasmic reticulum come to be?

Organelles are sub-cellular compartments in cells. However prokaryotes don't use organelles to organise their intracellular space. Evolutionarily, there is evidence that mitochondria and ...
3
votes
2answers
380 views

Why has our nose evolved with the nostrils facing down?

For most animals, the whole bottom of their face sticks out and they have a snout with a mouth and nose at the end. But humans have a flat face and just a nose that sticks out. We used to have the ...
2
votes
0answers
34 views

Neuroscience behind the crash

After experiencing things like stress, intense exercise, or using drugs such as caffeine and amphetamine, subjects often assume a depressive and lethargic state afterwards, known as a "crash." What is ...
0
votes
3answers
64 views

how to find accurately the closest species to my plant species?

I'm working on some bioinformatic analysis of a non-model woody plant within the family with least information. So, I'm looking for a closest species to my plant. Any suggestion would be highly ...
2
votes
0answers
17 views

How to calculate the number of sterile insects that must be released in SIT?

The sterile insect technique (SIT) is used to control insect pests through overwhelming the population in sterile males. The increase in sterile males released into an environment causes the increase ...

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