All Questions

1
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0answers
8 views

Recombination frequency as a function of genomic location in E coli?

Are there any databases or papers that give recombination frequency as a function of position in the E coli genome?
14
votes
1answer
191 views

Paralogous genes in genome-wide association studies?

Has anybody tested if paralogous genes are over-represented among the genes identified by genome-wide association studies (GWAS)? For example, if a GWAS study finds 200 genes associated to the ...
6
votes
2answers
96 views

Does muscle get bigger by increase in size of individual cells or increase in number?

Somewhere in the back of my mind, I have the claim that a muscle never increases its amount of cells but, if the muscle gets bigger, it's simply because individual cells get bigger. The book Anatomy ...
2
votes
1answer
44 views

How small does a nanobot have to be to “swim through the brain” and access any neuron it wants to?

I read on this question What is in the space between neurons in a brain? that there is actually not much empty space in a brain. But my question is slightly different. Is there a visual demonstration ...
1
vote
0answers
9 views

Slicing cell cultures frozen in vitrified ice with a laser for CryoEM

Could a cell culture frozen in vitrified ice for CryoEM be effectively sliced into thin planes and resolved images produced? I was thinking if this could be done to get images from inside a cell.
1
vote
1answer
15 views

Centriole genes Knock-out Experiment in Common experimental animals?

Anyone know of any experiments that have knocked out the genes for producing centrioles in a worm, mouse, fish, fly or whatever animal? Are the genes for centrioles even identified? It has been shown ...
23
votes
1answer
1k views

Ripening bananas artificially: What is the biological reason

I am a resident of the tropical island of Sri Lanka, and we have a strange traditional method to ripen our bananas quickly. What we do is this: We dig a pit in earth that is enough to put the whole ...
10
votes
3answers
268 views

How does a person get AIDS?

I am inquisitive to know about how a person contracts AIDS. Among the common masses it's still the belief that having sex with multiple partners causes the disease but that is not the case when read ...
1
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0answers
25 views
1
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1answer
27 views

Where do I purchase a fly with the collagen tagged?

Where can I purchase a fly with tagged collagen? My senior undergraduate research paper is observing the collagen in larvae with normal diet compared to larvae with an experimental diet. I need ...
3
votes
1answer
57 views

Do human visual functions degenerate due to genetic factors or by external factors?

Does eyesight primarily deteriorate 'naturally' due to genetics (genomic/epigenomic factors), or due to external factors such as normal wear and tear, or disease? By normal wear and tear I include ...
1
vote
0answers
24 views

if woman could live to the age of 150 at what age would they go through menopause? [closed]

Ive been wondering this for a while, I watch star trek and other geeky stuff (no offense.) but i would like to my question if you could give to me, if humans could live up to 150 of age or past that ...
1
vote
1answer
20 views

Is the nuclear envelope present in G1 of interphase?

Is the nuclear envelope present in G1 of interphase of eukaryotic cell? If so how does a method like Calcium mediated transfection get DNA past the nuclear envelope?
1
vote
1answer
24 views

Confusion over role of current/potential in Nervous system?

I am taking a course on the nervous system and I am do not have any physics background. Therefore, I would like to know, what are we precisely talking about when we talk about current in the nervous ...
1
vote
1answer
86 views

How to translate a blood type used in Eastern Europe?

What are the I-IV blood type descriptions shown below (commonly used in Eastern Europe), and how do you translate them into the ABO-system?
2
votes
1answer
39 views

human immune system

The common cold and [some?] types of influenza are self-limiting. Some microorganisms cause self-limiting diarrhea. Is tuberculosis [potentially] self-limiting or not? To put it another way, suppose ...
4
votes
1answer
49 views

Comparative leg sizes

When I was a child, my father showed me the classic essay "On Being the Right Size", J. B. S. Haldane. It talks (among other things) about how large animals need stockier legs to support their ...
7
votes
1answer
162 views

What is the fastest way to build an alanine scanning library?

For interfacial studies, I would like to build an alanine scanning library for one of my proteins examining 20 sites. I will ultimately express the gene using E.coli cell-free protein synthesis. I ...
5
votes
2answers
208 views

poor RNA quality from zebrafish embryos

Does anyone routinely do RNA isolation from zebrafish embryos? I have embryos from different stages but all below 24hpf. This is the protocol I follow: Take 10-20 embryos Wash once with milliQ ...
0
votes
1answer
23 views

Does vitamin D form crystals in the blood with calcium and magnesium?

I read on a vitamin-D product (2000NE) that I should not use calcium and magnesium with it, because it can result crystal formation in the blood. I googled, but find anything about this. Is it true? ...
14
votes
2answers
340 views

Why was it so hard to decode the corn genome?

My teachers growing up told me it was impossible to decode the maize genome. But yet its been done. Why was decoding the genome so significant, and what made it so difficult?
8
votes
1answer
100 views

Pancretic Acinar Cell - ATP, calcium concentration data

I need to find a decent source of data for concentration of ATP and calcium in the pancreatic acinar cell. So far all I can find is ATP or calcium 'levels' based on fluorescence , which are not ...
3
votes
1answer
62 views

Hair loss in a submarine?

Biologically, how critical is hair loss on a submarine? What is the prolonged exposure of a navy officer going to do to that person, say over a year or even more?
1
vote
2answers
54 views

Is there a difference between polarity and hydrophobicity?

From literature the two terms seem to be interchangeable when discussing protein domains and motifs. But biochemically, what are the specific differences between these two terms? For example what is ...
1
vote
2answers
21 views

How does the cell regulate different metabolic pathways?

I heard somewhere that cells use different nucleosides bound to triphosphates e.g. ATP, GTP, CTP and other modified compounds: NADH, NADPH to distinguish between different metabolic pathways and so ...
0
votes
1answer
157 views

Need of X or Y chromosome protein after meiosis

After meiosis each spermatid get either the X chromosome or the Y chromosome. I know that the 4 spermatids formed from 1 spermatogonia are connected by cytoplasm and so the proteins made by X or Y ...
0
votes
1answer
46 views

How to separate peptide on SDS PAGE?

I want to separate 1600 Da peptide on SDS PAGE, on 20% GEL I didn't get any band, How can I separate on PAGE? Can I use 25% SDS PAGE?
1
vote
1answer
31 views

Does the cellular response to every receptor work the same way?

I heard somewhere that activating any receptor results in the same intracellular response (signaling) which involves NF-κB. If that is true, I hardly understand how the cells distinguish between ...
15
votes
3answers
2k views

Is there any use of CO₂ in human body?

We all know CO₂ as a waste product of metabolism . Does CO₂ have any helpful role , apart from having a role in pH of blood ?
0
votes
1answer
34 views

Do hairs in the ear respond to things like shampoo?

Shampoo and conditioning products make claims to be the end all be all in hair care. I doubt that they are so advanced "growth formula/anti-breakage/oily treatment". Have any of the claims been shown ...
9
votes
3answers
2k views

Was the mitochondrion or chloroplast first?

I still don't know if the mitochondrion or chloroplast was first? I've looked for it on the internet and in various books but haven't found anything. Does anyone have the answer and a theory which ...
1
vote
1answer
45 views

How can I get brighter DNA bands?

I amplified my DNA with real time PCR. The amplification curve shows good amplification but not a single band is observed in my gel after gel electrophoresis. What would be the possible reasons? I ...
0
votes
1answer
14 views

Is there any merit to Dawn dish soap killing fleas on dogs?

My Fiona had a completely raw tail from biting. I saw severe skin scaling (dandruff) and checked her for fleas. She is old so her stomach hair is sparse. I was always taught to check belly and inside ...
0
votes
0answers
12 views

Ambidexterity Advantages and Disadvantages? [duplicate]

I was looking into training myself into being ambidextrous, what are the neurological and physical advantages and disadvantages of learning (not being born with) ambidexterity [if there is a ...
0
votes
0answers
14 views

Difference between conduction in unmyelinated axon and in myelinated axon [duplicate]

I understand that on axons dendrite, receive the stimulus and through passive conduction/graded potential (i don't quite understand that) summation would reach the trigger zone of the axon or axon ...
3
votes
1answer
43 views

Which is better against genetic mutations? Asexual or Sexual Reproduction?

In terms of genetics, which type of reproduction is better against adverse mutations? I understand a bit of Muller's Ratchet—in which asexual organisms accumulate a number of deleterious mutations in ...
0
votes
1answer
40 views

Do ants feel pain?

I have watched video on youtube where guy pours molten aluminium into fire ant colony to make casing. In the comments below there's huge discussion on is that a right thing to do. I am on the side ...
2
votes
1answer
36 views

Confusion regarding niches in evolution theory

This is the definition of a niche from Crash Course: An area of the environment that requires a special set of skills or traits to extract food and reproduce. Obviously, this version of the ...
1
vote
1answer
30 views

What kind of animal can do this?

When I was moving to another house, I found this plastic bag on the top of the cabinet of my old house. It looks like someone cut it all with a scissor, but no one have access to my bedroom, and it ...
0
votes
0answers
9 views

book on stem cells

Could someone advise a good book on stem cells? I know almost nothing about them, but have a good background in biochemistry. Want to know where did they located in the body (the niche). How did they ...
5
votes
3answers
56 views

Why don't fish groom each other?

Fish are often plagued by external parasites, which are presumably difficult for them to remove. There are well known cases where large fish come to coral reefs and allow smaller fish to pick off ...
3
votes
1answer
46 views

Weird gelatinous substance in highland bog

I recently went walking in the highlands in Snowdonia, Wales and we came across this: Can anyone explain what it is? My guess was some kind of fungus but I'm not positive. The ground was very water ...
1
vote
0answers
14 views

Criteria for electrophysiological threshold

As opposed to action potential thresholds (which are yes/no events), electrophysiological thresholds of compound action potentials are arbitrary. Mostly a certain noise level is picked and when the ...
2
votes
1answer
25 views

What is the mechanism responsible for the 'delay' in delayed rectifier potassium channels?

I've been trying to find a comprehensive explanation concerning the nature of the 'delay' in neurons' delayed rectifier potassium channels. As it's written in my intro to neuroscience textbook, these ...
0
votes
1answer
22 views

How do fish communicate?

Fish, as far as I know ( of course there may be exceptions) , don't have any vocal organ...but they are proven to be social...so how do they manage to communicate with each other...on land, organisms ...
2
votes
2answers
137 views

Importance of Double Helix DNA Structure

Gene expression involves transcribing only one strand of DNA molecule. So i was wondering what are some biological advantages of the double stranded DNA?
0
votes
0answers
18 views

Why vivipary is not found in all mangrove plants?

An interesting characteristic feature of mangrove plants is vivipary or viviparous germination...but some notable members of the family like Heritiera sp.( there is even a mangrove forest named after ...
2
votes
1answer
38 views

What's the meaning of this notation?

In Wang et al., the authors state on page 663 at the top that Furthermore, Bax-/- Bak-/- cells were completely resistant to paclitaxel-induced apoptosis. What's the meaning of the ...
4
votes
2answers
587 views

Why does the oxygen produced in the photosynthesis come from water and not CO$_2$?

In the photosynthesis equation $$6*CO_2+6*H_2O+sunlight\rightarrow C_6H_{12}O_6+6*O_2$$ the only place where we have 6 molecules of $O_2$ is in the $6*CO_2$. Then it reacts with $H_2O$ to form ...
2
votes
1answer
42 views

(Updated question) Problem with Fold-change mean compared to absolute data (in qPCR)

For the problem below I am aware of the statistics involved but just can't get my finger around the following: In biology we use qPCR to measure gene expression or basically number of mRNA copies. It ...

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