-1
votes
0answers
21 views

diuresis vs polyuria [closed]

Are polyuria and diuresis the same terms, if not then what is the difference between them , as both terms reflects excessive production of urine. greatly obliged to one who help me understand the ...
1
vote
3answers
70 views

What is the actual storage form of energy in muscles? ATP or Glycogen?

I was asked this question in my latest exam. I think the answer is Glycogen because ATP doesn't store energy for a long time so it isn't the ACTUAL storage of energy. Some classmates argue that in ...
4
votes
1answer
35 views

Do animals' facial expressions have similar meanings to humans'?

In the following pictures, the dog seems to be smiling to the camera. People staring at these picture also tend to feel comfortable and relaxed, presumably because they think it's very happy playing ...
0
votes
1answer
59 views

What percentage of a Neanderthal's DNA could be in a Denisovan?

My questions arose from an online course video at 3:11-19 The professor mentioned that the Neanderthals were inbred with their cousins breeding together but the Denisovans were very diverse , with 70%...
0
votes
2answers
35 views

Genes that exist in old Affymetrix platform but not in the newer one

I am using two gene expression datasets from an Affy U95Av2 platform and an Affy U133 Plus 2.0 platform. When I map the Affy probe names to HUGO gene names, there are thousands of genes which exist in ...
0
votes
0answers
15 views

Post-translation modifications of proteins that are regulated in breast cancer [closed]

I have a set of proteins which are up regulated in breast cancer. I was asked to find post-translational modifications (PTMs) for them, which I found based on databases but my question is that, what ...
5
votes
2answers
145 views

Does the hepatic portal system form capillary beds?

Does the hepatic portal system form capillary beds? If so, is the capillary bed coordinated with that of arterial capillaries? What review paper might I look in?
2
votes
1answer
52 views

What contributes to the variation of protein sequence across different species?

What contribute to the variation of protein sequence across different species (e.g. phenotype, environment, evolutionary pressure) and how do those factors contribute to the variation? I have tried ...
1
vote
2answers
26 views

Techniques for detecting phosphorylation sites in proteins?

I would like to know how phosphorylated sites in proteins are detected in practice. I read some papers where the authors were talking about mass spectrometry techniques. But my question is that why ...
-1
votes
1answer
41 views

How does imatinib recognize the constitutively active Abl-BCR even though it binds to the inactive conformation?

In chronic myelogenous leukemia (CML) ABL-BCR is constitutively active (always on) and it can be inhibited by imatinib and dasatinib. A study says that imatinib binds to the inactivated state of the (...
0
votes
0answers
20 views

Hybridization of an Indo-Aryan ethnic group and a Tibeto-Burmese ethnic group

The state in which I reside houses these two distinct ethnic groups. Physical Traits of the Indo-Aryan group Height:Medium Eyes:does not posses epicanthic fold Nasal bones:is not flat and broad ...
0
votes
1answer
49 views

Examples of biological turing machines [closed]

Are there any examples of biological Turing machines? And what can they do?
0
votes
0answers
7 views

Obout oxygen presence in krebs cycle [duplicate]

Q- If oxygen is not utilized in the cycle then why it is present in the Krebs Cycle?
1
vote
0answers
15 views

What is this insect found commonly in coastal India? [duplicate]

I have lived in two cities on the western coast of India and I have seen quite a few of these insects(?) in both places. It basically has an outer cocoon of sorts, which looks a lot like dirty ...
0
votes
1answer
34 views

Find the concentration of free receptors in a solution of 90% free ligand and 10% receptor-ligand complex, knowing only the value of kD

I could use some guidance on how to utilise the equation for the disassociation constant kD to find the concentration of free receptors [R] in a solution containing 90% free ligand [L], and 10% bound [...
0
votes
1answer
40 views

Why does meiotic recombination disrupt the independent assortment of genes on the same chromosome?

There are many sources that say that genes that are "linked" by being on the same chromosome assort with each other -- that when an allele is passed on that the gamete containing said allele will also ...
-1
votes
0answers
8 views

After how many generations our family resemblance change altogether? [closed]

I observe that one grandchild might be more different from his grandfather than his father, if so, obv he will be having more differences from his grand grand father.. After how many generations or ...
1
vote
1answer
215 views

sodium chloride and amylase activity

So, I did an experiment on the effect of sodium chloride on amylase. and I found out the higher the concentration, the slower the activity. Therefore, is it valid to make the assumption that when we ...
0
votes
0answers
38 views

Can defibrillation (cardiac arrest treatment) be done with a vehicle spark plug? [on hold]

Can successful defibrillation (restarting the heart after cardiac arrest) be done with a spark plug from a vehicle (possibly offroad vehicle)? Is it POSSIBLE for this to work? Let's say you are stuck ...
0
votes
1answer
27 views

Distance to source populations and/or environmental gradients?

How do you disentangle the effects of distance to source populations and environmental gradients when the environmental gradient occurs in the same direction as the source population? For example, ...
0
votes
1answer
53 views

Beta Sheets vs Alpha Helix - Strength

Is there a hard and fast rule of which one is stronger than the other, or does it depend on their context in a protein?
2
votes
2answers
202 views

Coalescence time: Is it different for haploids and diploids in population genetics?

I'm trying to model Cyanobacteria cells divergence in 2 populations with mutation rate $-\mu$ and I need to verify my model with a valid theory. I don't have much biology background and all the ...
4
votes
2answers
99 views

Why don't antibodies generally bind to food and drugs?

Are these excluded thru central tolerance? What if you ingested something with a unique molecular structure that you hadn't ingested before?
4
votes
1answer
96 views

Synthesis of Fatty Acids Longer than 16 Carbons

I understand that the human body when performing Fatty Acid Synthesis can synthesize only until C16 (palmitate). However the ER has desaturases and elongases. I know that desaturases are used to add ...
1
vote
1answer
142 views

Species-area relation graph

When species richness is plotted vs area, the graph follows the equation : log S = log C + Z log A where Z is the slope of the line. Z values are usually in the range of 0.1 to 0.2 but if very large ...
4
votes
1answer
79 views

Is there a biological explanation for perceived deeper cognition whilst on cannabis?

Cannabis has been associated with literature, arts, and culture for centuries. There are a few features of the drugs affect on the human mind that account for this, however it remains illegal in most ...
2
votes
2answers
4k views

Age of shells on beach

As a child I watched tiny fiddler crabs living in conical shells, and many years later I find that people study fossil turritellids. So now I wonder: how old are shells, typically, that you see on ...
1
vote
1answer
19 views

How to calculate apparent diffusion coefficient (ADC) with example?

Can someone give an example calculation for the apparent diffusion coefficient (ADC)? There appears to be multiple ways that this can be calculated, e.g. as discussed here: http://www.ncbi.nlm.nih....
0
votes
0answers
14 views

What are extracellular matrix pathways?

I was reading a research paper dealing with acute myeloid leukemia and the term "extracellular matrix pathway" came up. What does it mean? I found literature on extracellular matrix, but I'm not sure ...
8
votes
2answers
364 views

Why is a heritability coefficient not an index of “how genetic” something is?

On his blog, Eric Turkheimer writes: [T]aken as a number, a unit of analysis, heritability coefficients are funny things to aggregate on such a massive level. What exactly are we supposed to ...
4
votes
2answers
9k views

Applying saliva to mosquito bites

Is it true that; when you apply your own saliva to a mosquito bite it would stop itching ?
-2
votes
1answer
65 views

What was the precursor of testosterone? [closed]

Testosterone evolved about 500 million years ago (says 8fact.com). What was the precursor of testosterone (if any)? If possible, what caused the 'precursor' to evolve?
6
votes
1answer
93 views

Can microdialysis be made in Drosophila melanogaster?

I've asked this before in stack overflow's cognitive science community, and someone recommended me to ask here: I've found a couple of studies using microdialysis on insects, but didn't found any in ...
24
votes
3answers
66k views

What is the difference between orthologs, paralogs and homologs?

These three terms are often misused in the literature. Many researchers seem to treat them as synonyms. So, what is the definition of each of these terms and how do they differ from one another?
-1
votes
0answers
38 views

TDCS - safe limit? [closed]

What is the safe limit for Trans-cranial Direct Current Stimulation (TDCS)? From what little I have read, people typically do 2 times a day, each time 20 to 30 minutes at the same place. So... is it ...
-1
votes
1answer
22 views

How are unnatural amino acids modelled using insilico tools?

When the structure of an unknown protein containing amino acids other than the 20 known natural amino acids is modelled which method is primarily used in bioinformatics to solve the structure? what is ...
0
votes
0answers
16 views

Is genetic engineering in the eye possible? [closed]

Is it possible for iodopsin (photopsin) in cone cells to be genetically engineered to become rhodopsin so that retinal convergence could take place and therefore give some degree of colour in low ...
7
votes
1answer
4k views

Why do people sleep with their eyes open?

It's a fact that some people sleep with their eyes open, but why does that happen? Is it normal behavior, not a symptom of any sort of disorder? Are there any (dis)advantages to sleeping with eyes ...
1
vote
2answers
52 views

What´s the origin of junk DNA?

Most eukaryotes posses a certain amount of junk DNA in their cell nuclei. What is (are) the origin(s) of this junk DNA, And is it realy junk (superfluous)?
0
votes
0answers
12 views

optimization of density gradient centrifugation

I'm trying to isolate a ~320kD protein (in oligomeric form) using density gradient ultra centrifugation technique. Can any one tell me that what gradient (sucrose or glycerol or trehalose or etc) I ...
3
votes
3answers
146 views

How is the size of a gene defined?

Is there an agreed definition as to how many nucleic acid bases constitute a gene? If not, why not? I'm not sure I understand how the exact sizes of genes are defined.
0
votes
1answer
40 views

A diagram of a crossover [closed]

How can one draw a crossover between ABK and aBk where genes A and B follow the Mendel's law of independent assortment and gene K does not i.e. K is linked to B?
0
votes
0answers
28 views

How do I know if the tRNA gene is under purifying selection from looking at a sequence dataset?

I'm having trouble figuring out how to tell if a tRNA gene is under purifying selection, just by looking at its sequence dataset. Such as this one:
0
votes
0answers
17 views

How to Determine Sufficient Time for Melanoma Survivor to Be Considered Low Risk?

Regarding melanoma, how do we determine the minimum amount of time that a patient is disease free for them to be considered low risk? We are attempting to do survival analysis on RNASeq data from ...
18
votes
1answer
294 views

Is it painful for the hen to lay eggs?

My little son just asked me this question. His mother used to complain about the excruciating pain she suffered when she gave birth to him. He is a compassionate kid and wonders whether the hen goes ...
0
votes
1answer
76 views

How can I find the most studied SNP of a gene?

How can I find the most studied SNP of a gene and diseases that the most studied SNP has been related to? I search in dbSNP database but I can't find it. What is the process?
0
votes
0answers
28 views

What empirical evidence of genetic assimilation is there?

There have been many articles arguing that we should view the phenotype in the center of evolutionary theory rather than the genotype as done in most population (or quantitative) genetics. A typical ...
10
votes
0answers
613 views

Why don't rats have a gallbladder, unlike other rodents?

It has long been known that rats do not have a gallbladder, though other species including humans, monkeys, cows, reptiles, dogs and mice, all have a gallbladder. In this paper from almost 100 years ...
1
vote
1answer
12 views

How do molecules signal pre synaptic neurons to activate? [closed]

How do molecules signal pre synaptic neurons to activate? and also is it more the structure or the elements in the molecule that allows it to activate the neuron also how do molecules bind to ...
0
votes
0answers
19 views

Skip estimateDispersions() DESeq2 [closed]

In my experimental design, I have 20 libraries, coming from 20 F2 interspecific hybrids, meaning every genotype is different. 10 individuals are tolerant and the other 10 are sensitive to a specific ...

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