6
votes
0answers
39 views

Basic Modelling in Quantitative Genetics

I am pretty bad in thinking quantitative genetics models. I am trying to get some basic understanding of modelling the evolution of a quantitative trait. I am therefore asking for help to analyze a ...
3
votes
0answers
24 views

Multiplex PCR, shorter amplicon inhibiting longer amplicon?

I want to run multiplex PCRs for my genotyping, with a primer pair targeting my construct and a primer pair targeting some housekeeping gene (sort of a built-in control). I designed the control ...
4
votes
2answers
49 views

A doctor might give bicarbonate (HCO₃¯) to a patient who is breathing very rapidly. What is the doctor assuming about the patient’s blood chemistry?

The answer is: The doctor is assuming that the rapid breathing is the body’s response to low blood pH. (Source: Campbell Biology) But this answer doesn't make sense. Why would the doctor give the ...
1
vote
0answers
38 views

Drosophila biarmipes gene annotation, transposable element?

When doing an annotation of a contig31 of Drosophila biarmipes genome, the gene predictions(in orange, red, green, tan, blue, brown, and gray) picked up numerous possible genes in the area circled in ...
0
votes
0answers
43 views

Does embryonic development mimic (partly at least) the evolution of organisms on earth?

What do we know about the forces/mechanisms which lead to this seemingly "fast forward" evolution stages of the embryo? What are the theories dealing with this idea?
1
vote
1answer
20 views

Human population growth - where can I find the data?

Out of curiosity, I'd like play around with data of human global demography. Where can I find data that describe the "per region (per continent for example) population size" versus time since the ...
0
votes
1answer
28 views

How does cancer of the larynx (laryngeal cancer) affect the respiratory system?

The larynx is part of the respiratory system and is responsible for producing sound (our voices). My question is how cancer in the larynx (voice box) affect the respiratory system overall? I ...
2
votes
1answer
32 views

Why doesn't mitochondrial DNA accumulate damage over successive generations?

From what I recall, mitochondrial DNA is very susceptible to damage from oxidative stress because it is a site where free radicals are generated and their DNA isn't packed into chromatin like nucleic ...
1
vote
1answer
37 views

Feeling of spicy

I have done a survey on my friend When everytime they eat something spicy, They will eat ice or drink icy water. First, Mostly they feel nothing but a cool sensation. However when they finished, they ...
-1
votes
1answer
30 views

Why Insect bites are itchy rather than pain? [closed]

i don't understand if some thing bites or hurt we feel pain, but its differ for insect bites, why so?
0
votes
1answer
16 views

Using Jpred to predict secondary structure

I'm trying to use Jpred to predict secondary structure for a protein sequence. When I run J-pred, I get a bunch of hits from PDB. I've also noticed these 'hits' are the same name as the templates i ...
6
votes
1answer
42 views

Chromosome picture, how to interpret?

In this guide i was reading for annotations, there is a diagram of chromosomes of D.mel, I am confused as to why the chromosomes are all attached to one another, is this picture taken in a certain ...
2
votes
2answers
41 views

Recommend good conversational books to learn about cell and developmental biology or biochemisty?

I'm an engineer by training and teaching myself the basics of cell and developmental biology. I'm using Scott F. Gilbert's Developmental Biology and Alberts' Essential Cell Biology right now, and they ...
4
votes
1answer
35 views

Evolution of dominance of alleles

Can someone tell me where can I find detailed text about mechanisms of evolution of dominance? Or, if it is possible, I would be grateful if someone will tell me about them here.
6
votes
2answers
83 views

The effect on the efficacy and potency of a non-competetive antagonist binding to the active site of the receptor (dose-response curve)

According to the book "Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy" by Golan et al, non-competetive antagonists can bind to both the allosteric site and the active site. I ...
1
vote
1answer
33 views

Identify chromosome location from gene nucleotide or amino acid number

I'm sure this is a basic question, but I couldn't find an answer anywhere. Let's say I'm provided with the location of an amino acid or a nucleotide (for example, which lists the location as the ACADM ...
-1
votes
1answer
35 views

Why in acute phorpyria? [closed]

I am having confusing about treatment of phorpyria . I read it somewhere that for treating phopyria hemin and glucose is given IV . Please give me an easy explanation of it
0
votes
1answer
26 views

One Gene and many proteins [closed]

Imagine a gene with $n$ exons and $m$ introns. How many proteins are possible from that gene? Would all the proteins be isoforms?
0
votes
0answers
33 views

minimum ratio of the shortest isoform to the longest one derived from one same parent gene

I want to know what is the minimum percentage of the shortest isoform/transcript to the longest one that derived from the same parent gene? Does it have organism specificity? What is the function of ...
6
votes
1answer
55 views

Extracting cell-free DNA

Has anybody had any success in extracting cell free DNA from plasma without using expensive kits? I've already spent a lot of my own blood trying to use standard phenol/chloroform methods with very ...
0
votes
1answer
44 views

Similarity between the human genome and archea genome in deep sea hydrothermal vents?

I'm trying to find some reference that shows what percentage of the human genome is similar to some organism from the domain Archea that lives near or on deep sea hydrothermal vents. Can someone ...
2
votes
1answer
43 views

What happens when we stretch?

From the wikipedia page on stretching: Stretching is a form of physical exercise in which a specific muscle or tendon (or muscle group) is deliberately flexed or stretched in order to improve the ...
5
votes
1answer
48 views

Do any birds have established “poke a predator's eyes out” behavior?

Is there a pattern/tactics of behavior in any birds species that consists of attacking a predator's eyes with its beak? I'm looking for established tactics, not 1 or 2 anecdotal examples.
3
votes
1answer
48 views

Bayes theorem for mutations

MEN 2A is a dominant inherited disease caused by a mutation in the RET proto-oncogene. The probability of being sick when you have the mutation of the RET proto-oncogene varies with age and is assumed ...
3
votes
1answer
56 views

D/L configuration for amino acids

Why would this be "L-cysteine"? This is taken from the answer key for my biochem final. From what I understand if the -NH3(+) is on the left then the alpha-amino acid is in the L-configuration. ...
0
votes
1answer
52 views

Mutations/deletions with CRISPR

I need to stop some protein from being active and searching for some universal way to do so. In mammalians. With CRISPR it is possible to knock-out the entire gene. But it's a little complicate ...
0
votes
1answer
50 views

Finding Rna-Seq dataset for C. Elegans (Caenorhabditis elegans)

I want to find a RNA-Seq dataset for C. Elegans to use it in RNA-Skim software. For those who does not know RNA-Skim let me explain it a bit. It is a tool which is used to quantify RNA-Seq data using ...
4
votes
1answer
35 views

How can a heart of human work if one of its valve is not working?

Yesterday I went to a hospital and heard a doctor say that one of the heart valves of a patient is not working. However, the patient was still alive and was healthy; the patient could walk and talk ...
3
votes
1answer
71 views

Any evolutionary explanation for human blood groups?

What is the explanation of people having blood types from an evolutionary perspective?
2
votes
1answer
58 views

How is protein cavity centre related to binding?

I am confused and I have the following questions: 1. What are (in the context of article below) protein cavity centres? 2. How are they related to binding? (Automated identification of protein-ligand ...
0
votes
0answers
19 views

Animal counterpart to global seed vaults

Is there a global 'animal' embryo bank (or something similar to it) like the Svalbard Global Seed Vault for plant life? I don't mean 'gene' banks because they are not as 'useful' as real seeds are. A ...
1
vote
0answers
41 views

Would it be possible to create a gel, holding viruses, that could alter human genetic code when rubbed in?

I was wondering if it could be possible to engineer a virus, that when it comes into contact with human hair follicles, it could alter someones natural hair color. Naturally blue hair anyone? ...
2
votes
1answer
90 views

Is homosexuality an adaptation in humans?

Homo sapiens have menopause - as some other mammals (e.g. some Cetacea) - a phenomenon where older females live for decades after the end of their own reproduction. Perhaps homosexuality, that looks ...
0
votes
1answer
24 views

Can a relationship exist that is mutualistic/parasitic/etc. but not considered symbiotic?

Wikipedia definition of symbiosis: "Symbiosis (from Greek σύν "together" and βίωσις "living")[2] is close and often long-term interaction between two or more different biological species." Wikipedia ...
0
votes
2answers
39 views

Why is my peripheral vision better for seeing in the dark? [duplicate]

I often walk around my house at night with the lights turned off and one night I noticed that looking straight at an object with very little light available made the object disappear from sight but if ...
0
votes
1answer
31 views

Synteny, genetics?

Could anyone explain the concept of Synteny relating to genetics? A picture would help. I tried read the wikipedia source along with another PDF ...
1
vote
0answers
40 views

Why is chemotherapy so expensive? [closed]

I have two questions related to the price of chemotherapy: I was told it was expensive, but was not able to put numbers on it. Where could I find information regarding the actual price of a given ...
3
votes
2answers
47 views

Determining how much energy a plant takes in?

I asked a question on WorldBuilding.SE, "Are diamond berries possible?". This led to asking a question on Chemistry.SE about the amount of energy required to burn a 1 ct. diamond (−6.527kJ). The ...
4
votes
1answer
52 views

Is it possible to express a mutant gene only in a specific tissue?

Imagine that someone tries to develop a knockout mouse for a gene, but this result in lethality for the homozygous. Is it possible to express that mutant gene only in a specific tissue of interest to ...
5
votes
0answers
50 views

Can we make a rough estimate of the number of generations since the origin of life?

According to what we've learnt : we can approximate the number of generations since the first human pretty much like us (depending what / who we talk about). we have an idea of the series of life ...
2
votes
1answer
39 views

Identification of a larva

Last week-end I was working in my parent's garden and when I dig a bit the ground, I found few larvas I never seen before. My father told me there are there every time when he's doing the garden ...
4
votes
1answer
87 views

During the process of correcting mutations via gene therapy, is the defective gene removed?

Just recently started learning about gene therapy, many websites explain that the corrected DNA can be added to the genome using a vector and all that. I just don't understand what happens to the ...
3
votes
1answer
36 views

Identification of a plant (in a pot)

I have in my flat a plant which sometime make strange flowers. When the start it looks like plastic stars: Then the flowers are opening after few days and looks like this: The smell is a bit ...
1
vote
1answer
24 views

What is the developmental basis of the placental sac?

The placental sac is the organ that provides nutrients to the embryo from the mother. My question is that, since this obviously involves a lot of complexity, where does the sac originate from ...
-1
votes
0answers
37 views

Is there a way to tell what the surface of a planet is like? [migrated]

Kepler-442b I'm doing a project in which I need to find a planet within our galaxy that might be habitable. I found this planet that is within its solar systems habitable range, and due to research I ...
0
votes
1answer
42 views

Advantages of gregarious vs solitary behaviour?

I'm trying to explain why birds (specifically wildfowl) are gregarious during the winter and solitary during the summer. I think that in winter, birds are gregarious to reduce the risk of predation ...
3
votes
0answers
18 views

Generate T2/T1 Phage Resistant E Coli

I would like to generate T2/T1 phage resistant Stbl3 E Coli to use in virus production. Is there a plasmid somebody has used that confers resistance, or is this done another way?
3
votes
0answers
22 views

From where is the pollen kit material secreted?

From where is the pollen kit material secreted? I think it the tapetum would be a good candidate, since it is provides nutrition to the pollen grains.
1
vote
2answers
23 views

Difference between taking tissue of cancer from secondary place or primary place

Are there any differences when a surgeon takes tissue from secondary place (for example from metastasis) rather then from primary place (from an organ where cancer is) for morphological research?
2
votes
1answer
23 views

Where does the exudate comes from during inflammation?

During inflammation transudate and exudate is formed by vessels. I would like to make sure if it comes from arterioles, venules, or both, and the reason why.

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