2
votes
1answer
39 views

How is the subunit molecular weight different from the native molecular weight?

I noticed that the native molecular weight for an enzyme is different from its subunit molecular weight. Why are they different? Aren't the genes needed to express the enzyme the same in the native ...
4
votes
1answer
33 views

Is there a karyotype database for human cell lines?

I'm looking for the karyotype of a specific cell line. Some karyotype are well known, such as HeLa or some carcinomas, but some are very hard to find, such as LG2 (B cells). Is there a database ...
6
votes
2answers
488 views

Is this species a variant of a red flour beetle?

Found this little guy crawling around the back garden - South Coast of the UK. The closest things I could find online (with an admittedly weak knowledge of where to look up these things, aside a ...
4
votes
1answer
52 views

Modelling insecticide net efficacy loss [closed]

I am currently doing some work on modelling the effects of treated nets usage on mosquito populations. Nets do not retain their maximum efficacy forever. They lose their chemical efficacy after about ...
6
votes
0answers
31 views

Selection for possibly less efficient egg transfer in Human Botfly life cycle

I have heard that the Human Botfly transfers its eggs through other invertebrates [1], and it strikes my curiosity that if an insect could simply land on its host directly to deposit its eggs, then ...
1
vote
2answers
162 views

Why don't mosquitoes evolve towards muting themselves?

Quite certainly, muted mosquitoes would be much more effective as far as their blood-sucking pursuits are concerned, since mosquito sound is predominantly responsible for sealing their fate (between ...
1
vote
1answer
48 views

Can all animals of the same species crossbreed?

For example, take Canis lupus, the species of dog and wolf. Within their species, can all dog and wolf types crossbreed? We can forget the logistics and assume this is all done through artificial ...
1
vote
2answers
73 views

Can you Transfer Cancer Between People via Saliva or other Bodily Fluids?

This may sound like a strange question. But could a Cancerous cell be transferred from one person to another from Oral contact e.g. Through Saliva, or other exchange of bodily fluids? I know that ...
0
votes
1answer
40 views

What is a selectively neutral genotypic change?

I am reading the paper "Neutral evolution of mutational robustness". Because I am new to neutral evolution, I have a few questions. Firstly, from my understanding, genotypic neutrality means the ...
3
votes
1answer
38 views

Cause of Crease in Drupe Fruit

What causes the crease through the pericarp of a drupe fruit (peach, nectarine, olive)? It may just be in exocarp as @Ilan pointed out, but I assumed (perhaps wrongly), that the division continued ...
1
vote
2answers
54 views

Introductory book in genetics? [duplicate]

I am working in the field of neuroscience with a background in computer science. I try to find new ways of analyzing brain imaging data (mostly MRI, EEG, MEG, fMRI) with modern machine learning ...
2
votes
1answer
82 views

What is the difference between Single Nucleotide Polymorphism (SNP), Mutation and Structural Variation(SV)?

This is a question which plagues many people and today I was wondering it myself while writing a grant. Indeed, I've seen many people use the terms interchangeably, but they are all very different ...
1
vote
1answer
45 views

Bacterial capsule vs. slime wall

I've read that the bacterial capsule protects the bacterium from phagocytes and prevents water (and nutrients, possibly?) leakage from the bacterium. A less organized and less dense version is called ...
2
votes
1answer
33 views

Do we have evidence of heritable personality traits in chimpanzees?

I have read that chimpanizees have distinct personalities. Do we have evidence of heritable personality traits in them?
1
vote
0answers
30 views

Different names in paired-end sequence files

I am aligning paired end sequence reads using bwa mem and I get an error saying that ...
5
votes
3answers
135 views

How can a ligand be an integral membrane protein?

My background is in mathematics, and not biology, so please bear with me. I am currently working on a project involving the effects of Epidermal growth factor treatment (EGF) on cell migration. I am ...
3
votes
1answer
65 views

What is the optimum length of abstinence for maximum ejaculation volume in humans?

There have been papers discussing this, and whether the abstinence period should be 1 week, 2 weeks or other [1, 2]. Some think the time to maximum ejaculation volume is even longer than this. doi: ...
-1
votes
0answers
16 views

Using bwa mem with barcoded sequencing reads

I am using bwa mem to align paired end sequencing reads of mine. I have a 6bp barcode on both the 5' and 3' ends of my sequences that should be trimmed and added to the header for alignment. ...
9
votes
1answer
1k views

What is the mass of a pigeon tail feather?

There is question at Space.SE If I drop a feather from orbit, would it burn up or “hit” the ground? there is an attempt to answer the question, but the mass of pigeon tail feather and possibly the ...
9
votes
3answers
169 views

Why are the organs for reproduction and urinary excretion combined?

We eat food for getting energy to our body parts, and we excrete the wastes through urine, feces, and perspiration. Why has nature combined the urinary tract with the genital system (urogenital ...
0
votes
1answer
119 views

How to calculate biological half life of a drug that is dose dependent?

I would like to calculate the half-life of a biological drug. This biological drug is said to have a biological half-life of: ...
1
vote
2answers
66 views

Why a continuous supply of energy is needed to support a weight?

What motivates this question is the apparent discrepancy between the concept of Work in physics and in physiology. Work in physics is defined as the dot product of the force applied to move a certain ...
3
votes
1answer
61 views

What is the genomic position of HLA-B*1502 variation?

I've searched the position and SNP ID of HLA-B*1502 variation. However, I couldn't find that where this variant exactly located on genome or HLA-B gene.
5
votes
1answer
50 views

Are there terrestrial plants that thrive on sea water?

Given the existence of coastal deserts such as in the picture below, I was wondering whether terrestrial plants can survive on sea water alone? If yes, why then do coastal deserts exist, instead of ...
1
vote
3answers
76 views

Trypsin and cell culture

I am doing an experiment where I have treat the cells with a drug and calculate their counts. I would like to know if is bad to trypsinize the cells in consecutive days i.e. twice within 48 hours. How ...
5
votes
2answers
53 views

Why is cisplatin a very potent antineoplastic for testicular cancer, but not necessarily for other cancers?

Cisplatin (structure below) is a platinum-based chemotherapeutic agent which is very effective in the treatment of some cancers. Its introduction was responsible for improving the cure rate for ...
2
votes
1answer
30 views

How high into the air are spores of molds commonly occurring?

I understand so far that most of the air surrounding us contains mold spores so that given the right environment and a food source they start to grow. I assume this is true for air close to the earth. ...
1
vote
1answer
39 views

Mitochondrial inner membrane

I know that the cristae of the inner membrane can be tubular or vesicular but I would like to know what are the functions of each .
6
votes
0answers
31 views

What is the fate of micronucleus DNA?

Micronuclei are cellular structures that are formed as a by-product of, usually, defective mitosis. The piece of chromosome in a micronucleus may, or may not contain a centromere and the DNA is ...
0
votes
0answers
24 views

To what extent do different species of plants help each other in the defense against herbivores?

Many plant species developed the ability to sense mechanical damage and herbivory attacks. In case of such, some produces airborne chemicals (among others), to signal not only it's other parts, but ...
3
votes
1answer
38 views

What makes a strong polyadenylation signal a strong signal?

I was wondering why is it that "AAUAAA" is a strong Polyadenylation signal whereas the rest of the polyadenylation signals show reduced cleavage and polyadenylation efficiency?
7
votes
1answer
122 views

If eating 100% fat 2 times more worth the energy I spend during the day, will I store body fat?

So in theory, insulin hormone is the one that tells the body "eat more. don't burn body fat". Alongside with glucose blood level regulation and turning excessive glucose into liver (which later goes ...
11
votes
4answers
3k views

Are trees the only source of large amounts of oxygen?

Trees use carbon dioxide and produce oxygen in the presence of sunlight. But is there any other source? If yes, are trees the most important source of oxygen, or is there any other source which ...
2
votes
1answer
41 views

How do I find the number of child terms associated with a specific GO term?

I am trying to figure out how to find the number of child terms associated with a specific Gene Ontology (GO) term using QuickGO, without just counting the amount of terms in a list. For example when ...
2
votes
1answer
69 views

Consequence of Plants as Incomplete Protein Source

Some years ago, in a 1000~ level biology course we learned that the DNA essentially encodes formulas for creating proteins from amino acids. While the human body can synthesize many many amino acids, ...
2
votes
1answer
46 views

GATK workflow for Cancer

I am just starting to learn to use bioinformatics tools. My university has a limited and expensive bioinformatics team, so I'm mostly on my own except for big questions. I am planning to use GATK to ...
11
votes
4answers
1k views

Will the heart keep beating if it is separated from the body?

The heart is a vital organ in our body, as it drives blood circulation. I was wondering if a heart keeps beating if it is separated from the body? If yes, then why?
1
vote
1answer
44 views

Leaves growing on a leaf of a Begonia

I've a Begonia species. Somehow it started to grow new leaves on top and right in the center of an existing leaf which you can see in the center of the image. Why is it doing this? Apparently it is ...
3
votes
0answers
28 views

Expected reproduction rate of a dandelion and/or fern

I am working a basic mathematical/computer simulation of an ecosystem, and I need to know the birth rate of each organism in my simulation. However, I could not find any data for how often a small, ...
3
votes
1answer
93 views

Do we need to drink less water in humid weather than in dry weather?

From my understanding, humid weather means that the air has a lot of water in it. Therefore, someone who lives in this kind of weather would be hydrating himself just by breathing. Does that mean ...
4
votes
1answer
64 views

Identify the plant

Can anyone tell me which plant or flower is this. I have found it in Darjeeling, West Bengal, India.
1
vote
0answers
35 views

Is there a comprehensive model of human attraction and sexuality? [closed]

I'm interested if modern (2015) biology has a comprehensive model of how human sexuality works. From my research, it appears that the drive for mating is primarily mediated by ...
1
vote
0answers
26 views

Can photosyntetic cells be genetically modified to grow at a faster rate?

I hope the question is not silly, but I wonder if a sort of genetically modified plant "cancer" could be used for carbon sequestration. For example, cancer cells like HeLa have been reproduced in ...
7
votes
1answer
80 views

What determines the number of chromosomes an organism carries?

This is an extension of this question about What limits chromosomal length?. I am wondering what could be the specific reasons behind the number of chromosomes an organism carries. In other words, ...
3
votes
0answers
14 views

Gene silencing: relative or absolute number of methylated CpG sites?

CpG content varies a lot across the human genome. What does determine a promoter to be silenced through DNA methylation: the fraction of CpG sites that are methylated or the total number of methylated ...
3
votes
2answers
50 views

Neomycin resistance gene in E. coli stb3 cells

We use a lentivirus packaging vector called pLenti_puro_DEST. We use puromycin to select for the cloned gene in 293T cells. However, the pLenti_Neo_Dest has been discontinued, so I'm cloning a ...
-1
votes
1answer
73 views

Choosing a book to gain general knowledge about biology [duplicate]

I will be first year undergraduate at Physics department next year and last year I was at the Medicine faculty. I want do double major in the second year of faculty with Molecular Biology and ...
4
votes
1answer
33 views

Why do some protocols require prewarming a liquid medium before inoculating?

For example, in this protocol for E. coli competent cell preparation, it says: Plate 10 uL E. coli BL21(DE3) cells on a LB-agar plate; incubate overnight (12 hours). Prepare 500 mL SOB medium ...
11
votes
1answer
70 views

What limits chromosomal length?

What are the upper and lower limits for chromosome length? Are these limits different in different species or kingdoms? If there is any limit, which cellular or molecular factors are reasons?
5
votes
1answer
38 views

One Sample, Different Methylation Values

I'm hoping that somebody here can explain this unusual result that I'm getting with some pyrosequencing data. I have bisulphite converted a few samples a couple of times over the years for different ...

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