15
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3answers
2k views

Transmission of epigenetic regulation through surrogate mother

I know the basics of epigenetics, but I do not know how epigenetic mechanisms are transmitted from parents to children (or if there is even enough literature to derive a consensus). My question is ...
15
votes
2answers
1k views

What's the difference between male and female?

As long as we only look at humans the differences are clear: males have chromosomes XY, produce sperm and don't get pregnant. Females have chromosomes XX, produce egg cells and bear babies. But when ...
15
votes
2answers
1k views

Why do we get runny noses in the cold?

The most annoying thing for me about being cold is a runny nose. Is there an advantage to having a runny nose when cold? What does having a runny nose achieve?
15
votes
3answers
1k views

Do probiotics survive digestion?

Pretty much this. I've been wondering if any of the yogourt and other "health" foods containing living probiotic cultures survive digestion to populate our intestines? If so, is there peer-reviewed ...
15
votes
3answers
2k views

What causes a 'stuffy' or 'runny' nose when you have a cold?

When humans get the common cold, a common symptom is a stuffy or runny nose. Is that the body's immune response or is that the virus's doing?
15
votes
1answer
1k views

Why does looking at bright light trigger sneezing in some people?

Why does looking at bright light trigger sneezing in some people? Are there any recent studies that have found a cause for this Photic sneeze reflex? The Wikipedia article only references studies ...
15
votes
1answer
886 views

How Do White Blood Cells Learn? Or Do They?

So I get the concept that a vaccine is a weakened form of a virus so that the body can "learn" to fight it and make a person immune to that disease, but how exactly does this learning take place? What ...
15
votes
1answer
521 views

How fast does the rotor in ATP synthase spin?

I'm sure the exact frequency varies, but does anyone know roughly how many revolutions per minute / second the rotating center part makes?
15
votes
1answer
123 views

Why does mint oil feel cold on the skin?

When putting (japanese) mintoil on the skin it produces a cool feeling. You can experience this, when adding it to your bath or using a spray with mint oil on your skin. The cool feeling occures ...
15
votes
4answers
363 views

Machine learning for light microscopy — problems to solve?

I would like solve some biological problems that would improve the state-of-the-art of biology or bioinformatics. In particular, I want to apply machine learning on light microscopic images. The ...
15
votes
1answer
557 views

How do porcupines keep from pricking each other while mating?

How do porcupines keep from pricking each other while mating? It seems like they would constantly be scratching each other.
15
votes
3answers
271 views

Defining paper(s) in epigenetics

For someone who is interested in learning about the discovery of epigenetics, which are the foundational defining papers in the area?
15
votes
2answers
263 views

Can methylation from DNA get copied to RNA during transcription?

Methylation on gene-body and 3'UTRs if copied to mRNA can potentially regulate post-transcription modifications or expression regulation. But I'm not sure if they are maintained after transcription or ...
15
votes
2answers
5k views

Why is glucose our primary source of energy?

Is there any evolutionary reason for glucose being the "main" molecule used as a source of energy, beginning with glycolysis and subsequently cellular respiration (after being converted to two ...
15
votes
2answers
936 views

Impact of Alan Turing's approach to morphogenesis

Shortly before his untimely passing, the computing pioneer Alan Turing published his most cited paper The Chemical Basis of Morphogenesis (1952). The central question for Turing was: how does a ...
15
votes
1answer
4k views

Why do we grow so much hair on our heads compared to our bodies?

I've been wondering about head hair, facial hair in particular. Human males can grow very extensive beards should they choose to not shave - however you do not really see this in our chimpanzee ...
15
votes
2answers
408 views

Can parts of a human brain be asleep independently of each other, or vary in the times required for them to fall asleep?

I know that some birds and marine animals can continue complicated activity (swimming, flying?) while one hemisphere of their brain is asleep. I'm interested if human brain has some parts of it that ...
15
votes
5answers
9k views

Origin, or source, of rhesus negative in human blood

This is my first post here, so please be gentle. I recently learned that I have Rh- blood (I'm A-), and was idly looking into blood types on Wikipedia. I was surprised to find that relatively few ...
15
votes
1answer
167 views

Haidinger's brush: Is this a by-product of the eye's physics, or are there any evolutionary grounds for it?

The human eye is, very subtly, sensitive to the polarization of light. This is an effect known as Haidinger's brush (see Wikipedia article of this name). What, if anything, is known or at least ...
15
votes
1answer
491 views

Is it correct that the body only responds to the most painful stimulus?

I'm rather ashamed to say that this question is partly based on an episode of House. I have previously heard that, if there are multiple simultaneous painful stimuli, the mind will only feel the ...
15
votes
3answers
788 views

Why do some trees have a life span, while some don't?

I have heard that there is no limit on the growth of trees, but then why do some trees, such as boxelders and poplars, tend to live shorter than redwoods, for example? Some advertisements for improved ...
15
votes
0answers
448 views

Additive genetic variance components from LMER in R

I've set up some dummy data in R which makes 40 genetically related lines, they are all siblings within a line so are genetically related by a factor of ½ thus additive genetic variance should be ...
14
votes
4answers
4k views

Are mitochondria dead?

In the video "What is Life? Is Death Real?", the subject of mitochondria is raised at 2:58. At 3:12, the narrator says "[mitochondria] are not alive any more: they are dead." What currents of thought ...
14
votes
3answers
5k views

Why isn't vomit corrosive?

Vomit comes from gastric acid, right? And in gastric acid there is HCl and HCl is corrosive (strong), how come when I vomit, it doesn't destroy things that it (as the vomit) hits (such as floor, ...
14
votes
3answers
4k views

What causes the development of antibiotic-resistant strains of bacteria?

I understand bacteria have become resistant to antibiotics due to selection pressures, but how do resistant bacteria process antibiotics when exposed to it, compared to non-resistant bacteria. Also, ...
14
votes
4answers
73k views

Why is DNA replication performed in the 5' to 3' direction?

DNA replication goes in the 5' to 3' direction because DNA polymerase acts on the 3'-OH of the existing strand for adding free nucleotides. Is there any biochemical reason why all organisms evolved to ...
14
votes
3answers
46k views

What is a coupled reaction and why do cells couple reactions?

I was wondering what exactly a coupled reaction is and why cells couple them. I read the wikipedia article as well as several others, such as life.illinois.edu but I still don't get it. Could ...
14
votes
3answers
1k views

Is the size of the genome across species roughly the same?

Chromosome number differs across species. Is the amount of DNA comparable between organisms, just being split into smaller chunks in those species with more chromosomes? Or do species have different ...
14
votes
3answers
976 views

What evolutionary explanations are there for death?

I know death and cancer doesn't hurt humans' reproductive success. It's not helping either. Why do we die? Why dying humans (all of us) are common? What's the point of dying?
14
votes
4answers
953 views

How many human proteins have a solved 3D structure?

I was wondering how many human proteins have a solved 3D structure. Is there a database with only human proteins? I looked at pdb but couldn't find a filter.
14
votes
2answers
363 views

Why was it so hard to decode the corn genome?

My teachers growing up told me it was impossible to decode the maize genome. But yet its been done. Why was decoding the genome so significant, and what made it so difficult?
14
votes
6answers
2k views

Online Molecular and Cellular Biology Video Lectures?

I am looking for video lectures to go through to guide my reading in intro molecular and cellular biology. I've had intro bio and I study evolutionary theory, but my molecule- and cell-level knowledge ...
14
votes
2answers
1k views

How to make a fake auditory signal?

My question is about making fake auditory signals. The ear collects sounds from the environment, which are transformed into a neural signal by the hair cells in the inner ear. This signal is sent ...
14
votes
3answers
5k views

Supercomputer Vs Human Brain

With supercomputers doing calculation in petaflops ($10^{15}$ Calculations per Second), have we crossed the speed of Human Brain?
14
votes
5answers
2k views

Why are some genes dominant over others? What is the mechanism behind it?

If I have a brown eye gene which encodes the protein that is responsible for the brown color and have a blue eye gene as well, what is the reason that my eye color is brown? How does one gene maintain ...
14
votes
4answers
3k views

Why do parasites sometimes kill their hosts?

It's bothered me for a while now. I understand why a parasitoid would do this, as it only temporarily requires the host, and that not all parasites kill their hosts. There seems to be no evolutionary ...
14
votes
2answers
1k views

Why do we like salt?

A few friends of mine told me that salt provides zero nutritional value to us, and in fact can harm our bodies. Now, these guys are medical students, and being an engineering student myself, I decided ...
14
votes
4answers
2k views

Can two humans with 44 chromosomes produce viable offspring?

It is known that there are very few individuals having 44 chromosomes, not the usual 46 chromosomes. One example is a male in China: the first article, the second article. The other is a female in ...
14
votes
3answers
2k views

What implications has the missing 2'-OH on the capability of DNA to form 3D structures?

The chemical difference between RNA and DNA is the missing 2'-hydroxyl group in the nucleotides that build DNA. The major effect of that change that I know of is the higher stability of DNA compared ...
14
votes
2answers
713 views

Does testosterone increase female sexual behavior?

According to my lecture notes testosterone generally increases sexual behavior. Given that it's generally thought to be the male hormone I'm not quite sure whether they mean that it also increases ...
14
votes
3answers
51k views

NADH vs. NADPH: Where is each one used and why that instead of the other?

I know NADH is used in cellular respiration and NADPH is used in photosynthesis. What difference does the phosphate group make that the same one isn't or can't be used for both? Is there a greater ...
14
votes
2answers
9k views

Why do people have antibodies against other blood types?

The ABO blood type divides each blood type according to whether they have the "A" and "B" antigen(s) (AB has both, O has none). People also have antibodies against the antigens they don't have (AB has ...
14
votes
3answers
640 views

Why don't our cells merge when their phospholipid membranes touch each other?

Membranes of our cells consist of lipid bilayer (with some other components mixed in). Why wouldn't those lipid bilayers glue to each other and make the cells merge? If you suppose that it's due to ...
14
votes
1answer
4k views

How does a plant grow before photosynthesis is possible?

During photosynthesis, a plant translates CO2, water and light into O2. I assume the carbon C is further used for the growing process. I wonder how the plant grows before the time where photosynthesis ...
14
votes
2answers
1k views

How do birds deal with their eyes drying out at high speeds?

My eyes tear up when cycling at 15 mph, which is nothing compared to bird airspeeds. Do birds continuously produce lots of tears and blink a lot, or do the eyes self-moisturize from the inside ...
14
votes
2answers
3k views

Will humans and animals be harmed by frequencies outside their hearing range?

The human ear (for example) is sensitive to frequencies from 20Hz to 20kHz. Any sound beyond that limit would not be heard by us naturally. Will it harm us (effect our ability to hear) when we hear ...
14
votes
2answers
172 views

Relationship between our microbiome and personalized nutrition

Recently, it has been asked whether there are 'metabolic types' between humans that can benefit from a sort of personalized nutrition. One answer suggested that one discerning factor could be the ...
14
votes
2answers
722 views

Why does mouldy food make you sick?

Bread gets mouldy pretty quickly, and my parents (both of whom are nurses) throw out a loaf of bread after a spot of mould is seen (because "if you can see one spot, it means the whole thing is ...
14
votes
1answer
1k views

What do viruses do during incubation period?

For example, there is an incubation period of around 1 to 3 days for common cold, and that of AIDS can range over to decades. What do viruses do actually do during the incubation period? What ...
14
votes
2answers
15k views

Possible? When a pregnant woman suffers an organ damage, fetus would send stem cells to the damage organ to help repair it?

I am quite sure that there is this blood-placental barrier between the mother and the baby so that nothing (except a type of antibody) can pass through it. But I remember reading somewhere that when ...

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