4
votes
1answer
70 views

Why humans have the temperature they have?

It is obviously very onerous to generate heat at all, although it has advantages. We don't have to lie on the sun like a crocodile to get warmer. And we avoid the freezing of our body water by out own ...
4
votes
1answer
39 views

Why do insectivorous birds migrate?

Living in northern latitudes, I have always wondered why do migratory birds invest so much time and energy to travel twice a year the vast distances between their breeding grounds and wintering areas. ...
4
votes
2answers
104 views

Does increased physical activity increase the rate of cell division?

Ever since learning that the shortening of telomeres is linked to aging I've tried to figure out what causes cells to divide, and if it's possible to slow down the rate of cell division through life ...
4
votes
1answer
26 views

When does exposure to an allergen increase / decrease allergy?

In immunotherapy a person is regularly exposed to an allergen to decrease the allergy. Yet apparently "repeated intranasal challenges ... induces robust allergic airway inflammation, " [0] So when ...
4
votes
1answer
139 views

Why mosquito bite is confined to a certain shape?

I think this problem should be asked in a physiology forum rather than biology@ stackex but I'll give it a try. So my question is simple - why a mosquito bite is usually confined to a certain shape ...
4
votes
1answer
57 views

relative-rate of evolution

I am supposed to calculate the relative rate of evolution of two sequences (human and sheep) with a chicken serving as the outgroup. The sequences are pretty long, so I will just create a short ...
4
votes
1answer
86 views

Do cancer cells give off specific chemical signatures?

Do cancer cells give off specific chemical signatures? Are these signatures different from normal cells?
4
votes
2answers
3k views

NaCl role in CTAB - DNA complex in DNA extraction

I have a question about the role of NaCl in the DNA extraction process. So for NaCl concentrations under 0.5M, CTAB and DNA molecules can create complexes. In those concentrations, proteins and other ...
4
votes
1answer
51 views

Is it possible to elicit transient gene silencing by using virus induced gene silencing (VIGS) in plants?

I am looking for a molecular tech' which could result in transient gene silencing in plants. The objective is to not make transgenic plant, but to use these tech' to silence a gene of interest for a ...
4
votes
1answer
223 views

RNA isolation from Drosophila head

I need to isolate RNA from Drosophila head. I basically chop the head off and first homogenize it with a homogenizer (similar to this: ...
4
votes
1answer
32 views

Dyes to bind to double stranded DNA?

Are there any commercially available fluorescent dyes that will bind only to double stranded DNA (not RNA, single stranded DNA etc.) for studying in vitro using confocal microscopy?
4
votes
2answers
93 views

Is there a standard reference for the importance of tumor heterogeneity?

In a recent post, Philip Gerlee highlighted the two biggest contributions of mathematical oncology to cancer research: (1) increasing focus on the progress of cancer as an evolutionary process, and ...
4
votes
1answer
142 views

Why plants (eg. parsley) can keep vitamin C despite all the sun?

I have read that vitamin C is highly sensitive to light. So, how could parsley, for instance keep its vitamin C as it's flooded with sunlight?
4
votes
2answers
96 views

Reference sequence for defining single nucleotide polymorphisms

Single nucleotide polymorphism (SNP) or genetic variation in general, by definition are relative to a reference sequence. When we talk about databases of SNP as in ("dbSNP—Database for Single ...
4
votes
1answer
123 views

Beetroot white skin mould

Does a mould make a beetroot poisonous or inedible ? Lemon's mould for instance, makes penicillin, but it's green there, and I'm allergic to penicillin, would the white mould produce penicillin too? ...
4
votes
1answer
82 views

Enlargement of thyroid gland

Why does thyroid gland enlarge both in hypothyroidism and hyperthyroidism? Hypothyroid goitre is due to lack of iodine in diet and hyperthyroid goitre (Exopthalmic goitre, Grave's disease) is due to ...
4
votes
1answer
248 views

Sexual selection in cats or other animals

I was wondering if you could answer some of my questions regarding sexual selection in cats (or any other animals). I would like to apologize beforehand for my incorrect term use. When it comes to ...
4
votes
1answer
54 views

Do local field potentials (LFP) create waves on the surfaces of nerve cells?

Are waves created by the LFP on the surfaces of neurons cell bodies? Since the cells have a resting potential, do these waves create harmonic oscillation of the membranes at particular frequencies? ...
4
votes
2answers
108 views

Is tactile perception two-dimensional or three-dimensional?

Is tactile perception two-dimensional or three-dimensional? Can tactile sense be mapped on 2-dimensional map of the surface of the human body or does human receive tactile signal as a 3D position ...
4
votes
1answer
103 views

Identification of this spider?

I find these in forests in Oregon, western half, though they're probably on the eastern half as well. They live under pieces of wood and bark, and have a small web across the ground. Mine will eat ...
4
votes
1answer
87 views

The mechanism of mechanoreception?

I am interested in knowing the molecular mechanism behind mechanoreception/mechanotransduction (i.e. mechanism behind receptor potential generation on mechanical stimulation). I know that most ...
4
votes
2answers
278 views

How is membrane capacitance related to the increased speed of saltatory conduction?

Here is the original question which inspired my question. As explained by the answers there, the reason saltatory conduction in myelinated neurons is faster than non-myelinated conduction is because ...
4
votes
1answer
66 views

What is the best way to orally administer a water insoluble powdered drug to macaque monkeys?

They typically need to be given ~150mg, once a day, and it'll last for two weeks. The drug is very water insoluble, becomes almost like a paste, not suitable for tube feeding. And yes, this is for for ...
4
votes
1answer
65 views

What evidence is there on the medical effects of circumcision?

If this is the wrong place to post this question, then I will delete it and post it were it belongs. I have heard many conflicting things about circumcision. I have heard that it reduces the rate of ...
4
votes
1answer
79 views

Is this ventricular tachycardia?

I am investigating the public data of this. Its specification ...
4
votes
1answer
50 views

Finding RNA Loops

I was rooting through the literature, but there is too much work on the topic of detecting loops in RNA and the RNA helices that go with them. Can anyone point to a good review on this topic or even ...
4
votes
1answer
128 views

Does conjugation support gene selection?

I have already posted this on chat but haven't got any response. A recent question on group selection stimulated me to ask this here. QUESTIONS: Why should bacteria conjugate? If we consider that a ...
4
votes
2answers
64 views

Question about the expression of MHC

Is it possible to express both the MHC class-1 and MHC class-2 both in one cell?
4
votes
2answers
85 views

Do all humans experience flatus regardless of their diet?

Flatus frequency is affected by diet, so I was wondering if flatus production solely depends on the food eaten, meaning that some people never ever release flatus because they don't eat any ...
4
votes
1answer
111 views

Natural enemies boost deep evolutionary fitness?

"Two species that reduce one another's fitness on microevolutionary (short-term) timescales can increase each other's macroevolutionary (long-term) fitness" Opinions? Intuitive Examples: ...
4
votes
1answer
71 views

How predictably will RNA polymerase not translate repetitive sequences?

I am working on an (expensive) synthetic construct, which happens to have many "repetitive" sequences within it that are integral to its function. Primarily, the two sequences that are worrying me ...
4
votes
1answer
171 views

What makes a DNA sequence motif a DNA sequence motif?

I've read about DNA sequence motifs, but still don't understand what makes some sequence a DNA sequence motif. Is this a well-defined concept? For, example, What are DNA sequence motifs? says: ...
4
votes
1answer
60 views

Generalism - specialism index in microbial ecology

I am doing research in Lipid metabolism in different yeast species and I would like to look into ecology of them. I would like to classify them to a Generalist/specialist based on different ...
4
votes
1answer
242 views

Are there any types of cancer that cause neurons to divide?

After birth neurons generally do not divide. But is there any specific type of rare cancer or tumour where neurons divide? And if there is such a cancer, then how is it possible for a neuron to regain ...
4
votes
1answer
158 views

Microarray data and analysis tools

Microarray has various uses, and to analyse the data a main function classification is used. There are many methods used to classify the data but what are the best and most frequently used methods? ...
4
votes
1answer
79 views

Large scale reverse transcription?

I need to make RNA:DNA duplexes. I can make 100 to 200 ug of mRNA through in vitro transcription, and I know how to use reverse transcription to make a cDNA library, but I have questions with this. ...
4
votes
1answer
2k views

Difference between mutation and DNA damage

What is the strict difference between mutation and DNA damage? As far as I understand it, a mutation is an alteration in the genetic sequence, having "tricked" the repairing machinery and thus ...
4
votes
1answer
42 views

What are the molecular mechanisms that make the turtle brain more resistant to hypoxia?

I know that turtle brains, particularly those of individual species that hibernate and burrow are particularly resilient to hypoxia and any tissue damage secondary to a hypoxic event. What are the ...
4
votes
1answer
120 views

Identification of this Salamander

This salamander was found in a small forest pond somewhat near the Oregon coast. In the area are many rough skinned newts and a small number of another type of salamander that I still can't find the ...
4
votes
2answers
692 views

How does formaldehyde/PBS or methanol fixation of cells affect lysosomal pH?

The question is fairly simple - does formaldehyde or methanol fixation in preparation for immunocytochemistry/immunofluorescent staining affect the pH of the lysosomes? Some background: I'm trying to ...
4
votes
1answer
1k views

What is a “mechanistic study”?

I believe a "mechanistic study" means a study where a medicinal product is being used but the purpose of the study is to investigate the patient or disease, not the medicinal product. How does this ...
4
votes
1answer
63 views

What is an explanation of the dual role of calcium hydroxide in teeth?

Calcium hydroxide induces dentine formation in permanent teeth, while it causes resorption of tooth in deciduous teeth. How is this dual role explained?
4
votes
1answer
524 views

What is the difference between “lineage restriction” and “differentiated” in terms of stem cell biology

Is there a subtle difference between these two concepts or are they basically the same thing? When I mean differentiated, I don't mean terminally differentiated.
4
votes
1answer
66 views

What is the advantage of the way eukaryotes initiate translation?

The eukaryote and prokaryote mechanism for translation is slightly different. Is there any advantage of the eukaryote translation mechanism ? Edit : I specifically want to know why eukaryotic ...
4
votes
3answers
131 views

Abnormal Prolactin Level [closed]

I want to know what makes the balance of the Prolactin abnormal. Is that related to the presence of a nodule near the pituitary?
4
votes
2answers
60 views

What animal's lower eye lid moves to upper one when closing eyes?

I know cock's lower eye lids moves to meet the upper one when it closes its eye. What other animals does this? BTW, "cock-eyed" can mean upside down, I think.
4
votes
2answers
151 views

Plant identification?

Can anyone identify the plant below? It's in a backyard in Pennsylvania, and the photo was taken today.
4
votes
1answer
100 views

Randomness in living systems

The point of my question is not to talk about events that are uncontrolled by living organisms. My question is about controlled randomness, or I'd like to say adaptive random process. Process that are ...
4
votes
1answer
120 views

How are blood vessels affected by UV and infrared radiation?

The lining of the blood vessel as an interface and boundary layer is of existential necessity to the life-support of mammals. My question is: How are major blood vessels and the blood vessel lining ...
4
votes
1answer
103 views

How animals maintain their body shape after development to maturity?

I've recently read a book on evolutionary-developmental biology for laymen, and it described how a fetus is progressively divided into more refined zones of genetic activity. These zones, kinda like ...

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