3
votes
1answer
354 views

How do I get a brighter DNA bands

I've been trying to a good contrast for my DNA bands, however I haven't been so successful. I've been running the ladders only to make sure I get a good contrast before further experimentation. I ...
3
votes
1answer
50 views

Significance of lipids in biological membranes…?

Membranes are specifically designed by lipids to maintain internal hydrophilic environment in narrow range.There are hydrophobic amino acids among naturally occurring 20 amino acids and as well as ...
3
votes
1answer
43 views

How do B memory cells provide immunological memory? Do they differentiate into plasma cells?

My text book doesn't say anything about how B memory cells actually ensure a faster response the second time the antigen is encountered. My guess is that they differentiate into plasma cells which ...
3
votes
3answers
91 views

Why do 6-8% of diphtheria patients do not develop natural immunity after being affected?

I am thinking of why some patients do not have natural immunity after exposure to the A-B toxin of diphthria. I think the A-B exotoxin is the key factor causing this disease and should trigger memory ...
3
votes
1answer
75 views

Chaos theory and population cycles

I have just begun to read about Chaos theory and have come across the statement that "Period three implies chaos." My question: Does any odd period imply chaos or only 3? If so, how can populations ...
3
votes
1answer
84 views

Why is Turner syndrome rarer than Klinefelter syndrome?

Turner syndrome occurs in 1-1000 to 1-5000 females, and Klinefelter syndrome occurs in 1-500 to 1-1000 males. Why is Turner so rare even though they both are caused basically by the same mechanism?
3
votes
1answer
345 views

Is the complement system a part of innate or adaptive immunity

I've been reading about the complement system, as part of the human immune system. The complement system is introduced as part of the article on innate immunity on Wikipedia. This classification makes ...
3
votes
1answer
137 views

Sporophyte and gametophyte

My textbook says that in both groups of seedless plants (vascular plants, non-vascular plants) the gametophyte is a free-living plant, independent of the sporophyte. I don't understand this statement ...
3
votes
3answers
75 views

Is there a downloadable list of all species along with their traditional classification?

I'm looking for a downloadable list of all known (or better said, online documented) species in this straightforward format, as an example the European Frog: Kingdom: Animalia Division: Chordata ...
3
votes
2answers
108 views

Modern immunology textbooks

I am looking for recommendations to good textbooks introducing modern immunology. Review articles, preferably modern (post 2000) would also be useful. Please, include a brief comment with each book ...
3
votes
2answers
177 views

Why are antibodies so expensive?

The amplification on vector transgenic microorganisms and the subsequent purification does not seem that complicated. Also, what are the processes that biotechnological industries follow, in detail, ...
3
votes
1answer
43 views

Where can I find a full genealogy of human cell types?

It is said on Wikipedia, that the precursor of blastocyst is a morula, and that the precursor of morula is a zygote. This gives us the part of genealogy tree of cell types. Unfortunately, no full ...
3
votes
1answer
890 views

What is the definition of “dry weight” and “dry cell weight”?

As I understand it, the dry weight of something is its weight minus the weight of its water content. Is this the definition? What about dry cell weight?
3
votes
2answers
3k views

How does extracellular potassium ion concentration and calcium ion concentration affect the excitability of a cell?

When extracellular $K^+$ concentration increase by a certain amount, excitability of cells is higher because the resting potential shifts toward a higher equilibrium potential of $K^+$, therefore ...
3
votes
1answer
52 views

Euthyrodism and goitre

I read in Tortora and Derrickson that goitre is associated with euthyrodism. How is that possible?
3
votes
1answer
59 views

Alternating Ovulation

I have often heard that right and left ovaries alternate in releasing ovum. Is it always true? What controls this rhythm? Is it simply because the other ovary is unresponsive to LH or FSH? If so, ...
3
votes
1answer
285 views

Negative value on linear gene expression in microarrays

I am starting to use microarrays and maybe this is a dumb question: Using Illumina microarrays, linear gene expression can be negative? Or maybe some artefacts have been introduced? And, in this ...
3
votes
1answer
56 views

What is the cause of the spots on this leaf?

On a hiking trip to the Alps I found trees whose leaves showed those spots you see on the picture. I am curious about what the cause is. Higher resolution pictures of front and back side.
3
votes
3answers
70 views

Would Bubling Oxygen Through “Dead Zones” Like A Fish-Tank Make Much Difference?

I am a dilettante when it comes to dead zones. I realize that they vary from fleeting algal blooms to continuous dead zones. For the continuous dead zones it would seem to me that adding a "bubbler" ...
3
votes
1answer
54 views

Does a large effective population size result in faster decay of linkage disequilibrium (LD)?

I am thinking about an invasive species that was introduced into North America just a few (<20) generations ago. Using microsatellite genotypes (105 loci), I have identified almost no significant ...
3
votes
1answer
64 views

Difference in reptile inner ear and otosclerosis

In reptiles, the sound is conducted from the tympanic membrane to the inner ear by a single bone. In the disease otosclerosis the stapes of humans become fused to the other middle ear bones( or to ...
3
votes
1answer
1k views

Why is FADH2 made instead of NADH in one of the reaction of Krebs cycle?

FADH2 is made in conversion of Succinate to Fumarate. Why is this so ? Why not NADH ?
3
votes
1answer
139 views

Identification of this fly?

So I find these flies every year in my mulch, and I've never seen them anywhere else. The mulch becomes full of their larvae, which I feed to my toad and lizards. There are so many that you can hear ...
3
votes
1answer
817 views

Neuromediator, Neuromodulator, Neurotransmitter?

Of these three words, perhaps Neurotransmitter is the most obvious. I took a look at Wikipedia page for Neuromodulation and found that this is pretty similar to Neurotransmitter too. I guess ...
3
votes
2answers
2k views

Why do kefir grains stop growing in soy milk?

Kefir is a fermented milk drink made with kefir grains. It usually is prepared by inoculating cow, goat or sheep milk with kefir grains. I would like to prepare the drink with soy milk, which worked ...
3
votes
3answers
189 views

What exactly is the neural receptive field?

Neural receptive fields map the spatial or temporal distribution of the data to individual neuron excitation, if I understand correctly, but I do not understand if receptive fields (especially in the ...
3
votes
1answer
121 views

Differences between right and left handed people

Are there any articles reporting any significant differences in behavior, attitudes, intelligence, appearance, etc., between right and left handed people?
3
votes
1answer
161 views

Precursor miRNA and a mature miRNA

What is the main difference between a precursor miRNA and a mature miRNA? It is often the case that we have more than one precursor miRNA but only one mature miRNA. The miRNA-seq data contains only ...
3
votes
1answer
871 views

How does a virus take control over the host cell?

When the virus integrates its DNA with the hosts and enters the lytic pathway, do the viral proteins that produced destroy the cells DNA? Do they deactivate it? Also does the cell function in the same ...
3
votes
1answer
114 views

Are any organisms known to use meiosis I to create non-identical offspring asexually?

So, there are numerous species of animals who use parthenogenesis, but to my knowledge the reproduction is clonal. That is, the offspring are identical to the mother. Are there any documented cases ...
3
votes
1answer
75 views

Understanding these SNP annotations

I am looking at the PharmaPGKB database for SNPs and trying to understand what the following annotation means: rs1801131 at 1:11854475 in CLCN6, MTHFR (VIP) Ok, ...
3
votes
1answer
118 views

Results of a complete DNA sequencing - are they 100% reusable?

Is that correct that a complete DNA sequencing (the whole genome) need only to be done once (per person)? After that is done, it the complete genome can be stored and once the new genes (and they ...
3
votes
1answer
140 views

What kind of caterpillar is this?

I've made a photo using the reversed 58 mm lens and my cropped DSLR: Could you please help? I really don't know where this came from. I found it in Russia.
3
votes
2answers
82 views

Is there a way to measure the amount of bytes that are possible to encode in a DNA molecule?

When I saw a DNA molecule for the first time, it kinda reminded me of a hard drive. It consists of slots and there are some possible combinations for each slot; in the hard drive these possible ...
3
votes
2answers
43 views

Have novel interactions or pathways been predicted by GRN or PPI data and later confirmed by experiment?

I've been learning about the gene regulatory network (GRN) and protein-protein interaction network (PPI) recently. I've found a huge amount of extremely interesting papers about how biological network ...
3
votes
1answer
523 views

Difference between “transcriptional activity” and “RNA expression”

I am working with a network object where the nodes are different events in molecular biology. Specifically; Catalytic activity of X, RNA expression of X, GTP-bound activity of X, Kinase activity of ...
3
votes
2answers
94 views

Connect the inner and outer space of cell with a wire, will there be electricity?

There is a potential difference, but ions can not go through wires, right? Though there is a electric field, but there is no electron source, I am thinking the answer is no, or will there be some ...
3
votes
2answers
215 views

variation in antigen binding site of antibodies

Antibodies or immunoglobulins are proteins made ​​by the immune system in response to alien(!) molecules. Each antibody binds to its specific antigen. This great diversity and specificity is cause of ...
3
votes
2answers
48 views

Are there inherent problems in simulating marine environments, as compared to terrestrial systems?

We cultivate a number of terrestrial organisms in greenhouses and stables where they live in completely artificial environments. This seems to extend far less to marine organisms, such as fish. ...
3
votes
1answer
75 views

Atomic force microscopy: depth penetration?

What depth penetration can one typically get with atomic force microscopes? (i.e. how far into the tissue can one image?). I have found numbers on acquisition times (minutes) and spatial resolutions ...
3
votes
3answers
170 views

Super-resolution imaging in vivo

Are there any microscopy modalities or techniques for in vivo imaging at higher resolutions than the diffraction limit? I was looking at this list: Super resolution microscopy, but they don't talk ...
3
votes
1answer
377 views

Do adipose cells divide in adults?

I have a dim recollection of having heard that when humans gain weight, adipose cells just get larger, rather than dividing. True?
3
votes
3answers
692 views

What makes urine smell acrid?

Occasionally, after someone's been, there is an awful acrid smell lying about long after them. What causes this? The food that they've eaten? Urea less dilute due to dehydration? If it helps I've ...
3
votes
1answer
182 views

What is the known maximum ranging distance of a bat's sonar?

Bats are known to navigate by using echo-location. How far away can a bat detect an object by its sonar?
3
votes
2answers
90 views

What are the different, high-level programs along which a eukaryotic animal cell can follow?

What are the different, high-level, disjunct (mutually exclusive at one particular point in time) programs or pathways along which a eukaryotic animal cell can follow? Examples of programs would ...
3
votes
1answer
633 views

How long can a unicellular organism live without nutrition? What happens after that? Does it depend on the domain?

Say I have three unicellular organisms: a eukariote, a bacterium and an archaeon. If I cut off nutrition from them at the same time, how long will it take for them to die? What will their death look ...
3
votes
1answer
157 views

Negative feedback in the fructose metabolism in liver

What happens in liver when large amount of fructose is consumed? I vaguely remember my biochemistry lecturer telling us that the enzymes that process fructose in the liver does not have negative ...
3
votes
1answer
1k views

What are the units of Q10 (temperature sensitivity)?

Q10 is the increase in a rate (e.g. activity of an enzyme) observed with a 10 degree temperature increase. According to Wikipedia: It is apparent that the units of R (e.g. mol/g/s) cancel out, ...
3
votes
1answer
305 views

What are samples of “Outlaw Genes”

I read this in a paper Keller and Ross describe their greenbeard gene as an ‘outlaw’. Admittedly, the comment is only made in passing, but are they correct? In this context an outlaw is ...
3
votes
1answer
346 views

Does caffeine increase the speed at which sperm travels?

I'm not even sure if this claim is true, but... This source states that Caffeine gives both types of sperm a boost, but the Y-sperm would get a little more of a boost. This article reinforces ...

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