0
votes
0answers
12 views

How Calcium regulated in myocardic AP and plateau phase?

The plateau phase is maintained by influx of calcium and outflux of potassium in the second stage: My conjuncture is that calcium transforms between two phases ionated phase (free calcium from ...
9
votes
2answers
1k views

How does a woodpecker not give itself concussions?

How does a woodpecker go about smacking it's head into a tree without killing itself?
2
votes
0answers
28 views

What bird makes this sound?

It sounds like some kind of crow but not really. Here is my recording: https://www.youtube.com/watch?v=4TsKFUugot8&feature=youtu.be#t=06s This bird always wakes me up at 04:00 and this started in ...
2
votes
1answer
29 views

What is the scientific name of this butterfly?

I have this butterfly but I don't know its scientific name. I think that it's a common butterfly which can be seen everywhere (btw, I'm in Taiwan.) Thanks for your help :D
1
vote
0answers
11 views

Review articles for best practices in modelling cellular signaling networks?

I wonder if you could suggest an accessible review article for best practices in computational systems modelling. Specifically, I would like to try to model a cellular signalling network that would ...
0
votes
0answers
12 views

Is there a definitive theory of how general anesthesia works?

Is it true that the method of action of general anesthesia is not exactly known? In other words, is there no conclusive theory of how it works?
2
votes
1answer
36 views

The pBR322 convention

What is the pBR322 convention? For example in the description of the pET28a vector we can find information that the sequence is numbered by the pBR322 convention, so the T7 expression region is ...
2
votes
1answer
49 views

A question about IPTG induction

I have found the information: `In the absence of lactose, the lac repressor binds to the operator sequence on DNA and bends the DNA by 40 degrees. This blocks access of T7 RNA polymerase to the ...
2
votes
0answers
21 views

Soft and Hard selection

Seems to me that these two sources (M. Whitlock, B. Wallace) use different definitions of soft and hard selection. M. Whitlock: Soft selection occurs when the relative fitness of an individual is ...
0
votes
1answer
54 views

what is the biggest known functional distance between an enhancer and its target gene (TSS) in cis?

since the title seems self explanatory; It would be nice if anybody could provide a reference. I'm looking for a paper that I belive stated around 1.5 Mb but anything above will be cordialy welcomed. ...
7
votes
2answers
1k views

How do we know the presence of light when our eyes are closed?

Last night I laid on my bed and tried to go to sleep with the light off. I closed my eyes (but hadn't gone to sleep). My younger brother touched the wireless mouse (which had laser) for the laptop. ...
1
vote
0answers
26 views

Effects on Bear Population [closed]

imagine in a given area or an ecosystem ,bear hunting is totally banned, but there is a scarcity of food for the bears. i want know what would be the future of the bear population?. and want to derive ...
0
votes
3answers
29 views

can recessive alleles produce codominance?

Maybe I'm confused by the term "codominance", but I wondering if codominance only occurs with two dominant alleles. Can two recessive alleles produce codominance in an individual? Likewise, can two ...
1
vote
0answers
17 views

Fast standing and the heart's insufficient accommodation of the increased venous return

Assume you are 45 minutes on the supine position. Furthermore: you stand all of a sudden and fast and without sympaticus activity. The venous return (smooth musculature of vessels) accommodates ...
1
vote
1answer
41 views

Does a top heavy population grow, decline or stabilize?

Imagine a population that has a larger proportion of older individuals than younger ones, what could possible happen to it in the future? I am guessing that if the older individuals reproduce, the ...
4
votes
2answers
51 views

Database of Multicellular and Unicellular organisms?

I'm trying to annotate a list of organisms taken from NCBI for cellularity (unicellular or multicellular). Does any of you ever found a database with association between an organisms' name or taxa and ...
1
vote
1answer
52 views

Convert gene name to uniprot ID

i have a list of gene name in a file CHRNB2 EGR2 GCK KRT14 LMNA FGF3 TK2 ABCC8 How can I map them to uniprot ID ? P.S I tried Uniprot "ID mapping" ...
2
votes
1answer
146 views

Why are men stronger than women?

What are the evolutionary explanations for why women are weaker than men (on average), and is this difference adaptive? I suppose that something puts pressure on men to be stronger than women, but I ...
1
vote
1answer
29 views

Can insects feel pain?

Insects do have a nervous system, even if it isn't nearly as complex as that of other animals. Can insects or other arthropods sense pain? Does their aversion to harmful stimuli suggest that they can ...
4
votes
1answer
50 views
2
votes
1answer
29 views

Why does temperature shock kill fish?

As is advised with most fish you should avoid sudden changes in water temperature (for example by introducing new water that hasn't been left to come to room temperature). I have, however, never ...
5
votes
2answers
864 views

If I squash an insect and it produces red “juice”, does it always mean it is a blood-sucking type?

If I squash an insect and it produces red "juice", does it always mean it is a blood-sucking type of insect? Or do some insects have red "juice" themselves, so the color is red on its own and not ...
2
votes
1answer
24 views

Heterochromatin production limitations

Currently playing with some ideas for a project and needed some guidance. I am wondering, both in Drosophila melanogaster and in general, is the amount of heterochromatin a cell/nucleus can produce ...
1
vote
2answers
96 views

Heterochromatin binding sites position information

I am working on a project and I'm trying to find data on the position of genes and heterochromatin binding sites such as HP1 in Drosophila melanogaster. Is this information available for the DGRP ...
1
vote
0answers
26 views

Kinesin-5 / cytoplasmic dynein spatial density distribution in neurons

is there some way to experimentally determine the density distribution of those two molecular motors in a Neuron? Fluorescence labeling would be impossible(?) as GFP markers would probably alter the ...
4
votes
3answers
140 views

Specificity of Protein Kinases in Signaling Pathways..?

In most of the signaling pathways the activated receptor when activates Protein Kinase through the action of secondary messenger, then these protein kinases almost always phosphorylate on the specific ...
0
votes
0answers
13 views

Are insects attracted to near infrared light?

Do insects see near infrared light? If yes, are they attracted to it at night, as they are to visible light sources? I am building something similar to a home-made trailcam with a Raspberry Pi ...
1
vote
4answers
68 views

Which point mutations in proteins are OK, and which cause significant change?

I heard that some point mutations in proteins are OK, like from alanine to glycine (I'm not sure, it's just an example), some will change the protein significantly. I want to understand deeper but ...
1
vote
3answers
42 views

FRET only works for interactions between 1nm to 20nm.

FRET only works for interactions between 1nm to 20nm. How can you be sure that the interaction that you want to study isn't less than 1 nm/greater than 20nm apart?
2
votes
2answers
374 views

Do females living on mountains have more RBCs than a normal male [closed]

I got this doubt when I was studying about haematocrit value. According to my NCERT textbook males have greater number of RBCs than females. But who will have more RBCs when comparing a normal male ...
1
vote
2answers
38 views

Hiding identical sequences in NCBI web interface

Sometimes there are identical sequences in Genbank/Genpept, most often coming from the same species but different strains. Ie if I look up "bacteria chitin synthase", the 624-aa protein from Dickeya ...
5
votes
1answer
93 views

Are there any cases of observed extreme speciation [closed]

Is there an observed (direct not indirect) speciation on record showing a species shift within the span of history of recorded science?
3
votes
2answers
80 views

Theoretically, is domestication of (virtually) any animal possible?

Looking at ones that manage well alongside us human animals, such as dogs and cats, we see that this is possible for evolved, distant animals to have heritable, preferable traits around people. ...
1
vote
1answer
29 views

Anaphase Microtubule Disassembly

Centromeres move toward the poles as the microtubules that connect them shorten. This shortening is due to the removal of tubulin subunits from the kinetochore ends of the microtubules. I'm confused ...
1
vote
0answers
25 views

What is Mycoplasma Lyo medium?

Used for instance in this article The role of genital mycoplasmas as pathogens - - are generally neglected by diagnostic laboratories in the United Kingdom, possibly due to the lack of a ...
3
votes
1answer
46 views

how can a pseudo coelomate like ascaris lay 200k eggs in a single day

as per this site the dimensions of eggs of ascaris lumbricoides are 78-105 microns and as it is shown in the pic down here only half of the body cavity would be used for storage of all the stages of ...
2
votes
3answers
89 views

What equipment would one use to modify a virus? [closed]

Would anyone be so kind as to give me a few examples of the equipment involved when modifying a virus? Otherwise my novel may end up reading Eva entered the lab and modified a virus. Not much back ...
4
votes
2answers
165 views

Species of this White Dove

I visited a bird enclosure close to where I live in Australia. The enclosure had several different species. The birds that stood out most were these doves sitting right along the fence railing, making ...
2
votes
4answers
72 views

Theoretically, what technique would one use to modify a virus so that it only affected a subset of the population?

I'm writing a novel and i would like to know some of the equipment and techniques involved with modifying a virus. Is it feasible for a virus to be engineered to only affect certain people? It ...
1
vote
1answer
27 views

A question on exclusion of study participants for an Exome genotyping array

I'm reading a paper that used whole exome sequencing on an African American and European populations to discover novel low frequency and rare variants associated with lipid levels & the risk of ...
1
vote
1answer
48 views

will an earthworm survive after covering its skin with a wet cloth

I am very curious about this question. I got this doubt when I was studying anatomy and physiology of the earthworm Lampito mauritii. It breathes through its skin (cutaneous respiration) and if we ...
1
vote
1answer
22 views

Investigating rare variants in ethnically different populations (European ancestry & African ancestry)

If you are investigating low-frequency and rare variants for a complex trait using exome sequencing, why would one consider using different populations (African ancestry and European ancestry) ...
3
votes
1answer
29 views

A question on ImageQuantTL

I am confused about using the ImageQuantTL application as a tool to analyse the Urea Gel. My problem is that I am not sure if the 'shape' for calculation should be the same for all samples (like on ...
2
votes
1answer
66 views

How does the Cuttlefish camouflage itself accurately despite being color-blind?

I have seen/read that the Cuttlefish is able to camouflage itself extremely accurately. I have also seen/read that they are completely color-blind, though see with very high contrast. How does the ...
2
votes
1answer
19 views

Calibration curve for single radial immunodiffusion

When we draw a calibration curve for single radial immunodiffusion, the curve does not pass through origin. Instead, there is a y intercept. Why does that happen ? Shouldn't zero antigen give zero ...
0
votes
1answer
43 views

Can skin become denser?

I heard that after injury or repeated damage bone becomes denser, can skin become denser as well?
2
votes
1answer
63 views

Can (any) human cells learn?

I'm not talking about single celled organisms, but actual cells in your body. Is there any evidence that they can learn to, say, navigate an environment or avoid an aversive stimulus like an animal ...
2
votes
0answers
42 views

Can a heterozygous allele show non-heterozygous expression in a family?

I'm doing a family study looking for novel cancer-associated variants in germ-line samples; the goal is to find candidate biomarkers which might be used for early detection. At an earlier step our ...
3
votes
1answer
39 views

What is the purpose of back-crossing mice for multiple generations?

Occasionally I will come across articles that refer to back-crossing mice of one strain onto the background other another strain (e.g., C57Bl6). They do not explicitly state the purpose for doing so, ...
1
vote
1answer
54 views

Is it possible for neurons themselves to manifest cancerous behavior?

From what I understand, one form of cancer is a faulty gene responsible for the programmed death of a cell. Not long ago, popular wisdom used to say neurons don't regenerate. However that is no ...

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