2
votes
1answer
29 views

DNA dependent RNA polymerase

How does a RNAP locate a specific gene? For instance, growth hormone has to be produced and the RNAP has to locate the gene. But the promoter (TATA box) will also be present infront of all cistrons. ...
1
vote
0answers
32 views

Can I explain the kinetics of a ligand looking at the ligand-protein co-structure?

Can I explain the kinetics of a ligand binding to a target protein (association and dissociation rates) by looking at the protein-ligand co-structure? Editing my question after a few comments: I ...
7
votes
2answers
119 views

What are some (bioinformatic) methods to characterize potentially novel gene transcripts?

I am working with a few novel transcripts of genes- before I confirm their existence experimentally, I would like to perform some bioinformatic analysis. I have already considered coding potential, ...
1
vote
0answers
20 views

why not classify organisms based on genetic distance? [duplicate]

When learning about "families of animals" in mid-primary school, my son asked me if there is not a better way to classify animals than by looking at them (they were taught that animals are grouped ...
0
votes
1answer
26 views

C Form DNA Base Pairs Per Turn

How does C-DNA have 9.33 base pairs per turn? The number of base pairs should be quantised. How can it be a decimal?
2
votes
0answers
52 views

What is the name of this tree? [duplicate]

I noticed this plant growing on the Azores islands. It has a surprisingly perfect distribution of branches, which gives it the appearance of a fake decorative plant. Does anybody know what type of ...
1
vote
0answers
38 views

Random small after-images of things not really there [closed]

I am 44 years old and have noticed that I often get small blotch afterimages that last for about 5-10 mins. Normally, everybody gets these when they look at a bright light. I seem to get these every ...
14
votes
2answers
1k views

How to make a fake auditory signal?

My question is about making fake auditory signals. The ear collects sounds from the environment, which are transformed into a neural signal by the hair cells in the inner ear. This signal is sent ...
3
votes
1answer
53 views

What are the most important factors influencing a person’s gut microbes?

You are your bacteria! The probiotics and the antibiotics... There has been on going discussions about how our gut bacteria is important for a healthy lifestyle. Figure 1: Schematic diagram ...
1
vote
0answers
22 views

Which pathway visualization software can I mouse-over the name to view molecular structure? [closed]

As the title implies, I'm looking to use a single pathway visualization program to learn pathways. All that I can find, like wikipathways, only show the names of the molecules, with an option to click ...
1
vote
0answers
11 views

Which anti-fungal compounds effective against Grosmannia clavigera?

Grosmannia clavigera ("Blue Stain Fungus") is the fungus introduced by Dendroctonus ponderosae ("Mountain Pine Beetle") when they infest their host (several species of Pinus). Are there any known ...
5
votes
1answer
56 views

Where do most mutations come from, mitosis or meiosis?

According to this (old) paper there are 10 times more mutations during meiosis than during mitosis. One reason for that is that recombination often causes replication error and therefore mutations. ...
0
votes
2answers
90 views

What are the programming languages important to learn for a geneticist or bioinformatician? [closed]

I am interested in learning more about both genomics and bioinformatics, with emphasis on genomics. I was told after taking an introductory course of genomics that the programming language "R" and ...
6
votes
1answer
65 views

What are these tiny dark red insects?

I found these creatures stuck to a leaf on my tomato plant in the greenhouse/glasshouse, in early June, in south Oxfordshire in the United Kingdom. They are each about 1-2mm in size. They didn't move ...
1
vote
0answers
17 views

Differences in structural target for LPS detection by LAL and MD-2/TLR4

I remember there being a significant difference in the pathogen-associated molecular patterns (PAMPs) used for detection of lipopolysaccharide (LPS) by mammalian cells and the Limulus amoebocyte ...
3
votes
0answers
34 views

Can two members of the same sex have a biological baby? [duplicate]

I imagine that this would work using a similar technique to dolly the sheep. For two females, the nucleus of an egg would be placed in a sperm which has had its nucleus removed. The 'female' sperm ...
0
votes
0answers
41 views

How calorie intake affects weight gain?

There are ton's of textbooks and websites that say that if you want to gain weight you have to increase your calorie intake. My question is how is it possible for a body to take in more calorie than ...
5
votes
0answers
63 views

How to fix a small pond that has become stagnant? [migrated]

I'm working in a park and we have a small pond a part of a river system that has become stagnant, mucky and smelly. The river that previously ran into the pond is no longer there and we'd like to be ...
2
votes
3answers
103 views

Blood urea nitrogen and usage of proteins?

I have been reading some books and am getting slightly confused. Here is roughly what I have read. The greater the blood urea nitrogen the greater the usage of proteins (since blood urea nitrogen ...
1
vote
1answer
37 views

Hodgin-Huxley model for a single neuron - continuation

As continuation to This question I have posted. Another set of questions is given for the same model : This time it is also given that for $t<0$ the membrane potential is $u_0$, and at $t=0$ it ...
2
votes
1answer
41 views

Extract protein sequences from a GBK(GenBank) file without scripting [closed]

How to extract protein sequences from a GBK(GenBank) file without scripting? I know that writting a script using BioPerl or Biopython can do this, but it is not elegant and daunting to beginners and ...
2
votes
1answer
55 views

How does Celiac's Disease cause people to stop growing?

In all of the sites I've looked on, one of the symptoms of Celiac's Disease is the failure to grow in children. Why would an immune attack against gluten cause stunted growth? Celiac.org states: ...
3
votes
2answers
121 views

Is there a short-term, very strong anesthetic, which can be blocked/delayed by other substances?

Question migrated from World Building SE. (For fictional use only, of course :) ) I am looking for an anasthetic which fulfills the following criteria: very strong effect, induces a comatose state ...
0
votes
0answers
28 views

View ABI chromatogram plots with python

I would like to view the chromatogram traces from a few ABI (.ab1) files. I would prefer to use python for this, or a function with python bindings, or at least some open source package such as ...
16
votes
4answers
2k views

Where’s the flaw in my proposed TB Treatment?

Ten years ago, I emailed a prominent lung specialist with my suggestion for a treatment for Tuberculosis. His lack of response led me to believe that the idea had no merit whatsoever – but I had no ...
0
votes
1answer
30 views

How reliable is SwissProt topology?

I am using TOPO_DOM annotations from uniprot databases to characterise the orientation of transmembrane features. Is SwissProt topology experimentally validated, ...
0
votes
1answer
34 views

What is the difference between options protein and replication in the NCBI database?

After checking the NCBI help page, I am still unclear about the difference between protein and replication interactions for HIV. ...
3
votes
0answers
36 views

Do High Triglycerides Invalidate Tests for Infections?

Blood donation websites tell you to avoid eating fats a few days before the donation, because when there is a lot of fat in the blood, they can't test for infectious diseases and must discard the ...
5
votes
1answer
81 views

Is it theoretically possible to restore the Tiger population to 100,000?

The current global Tiger population is roughly 5100 according to Wikipedia. With habitat destruction and poaching continuing and no effective improvement in conservation, most likely the Tiger ...
1
vote
1answer
30 views

Blood pressure measurement

When measuring your blood pressure in your arm, when you hear the sound to measure the systolic, is that sound NOT the heartbeat?
2
votes
1answer
58 views

Is the immune system suppressed during sleep?

Of course we have heard that during stress our immune system is suppressed. This leads me to wonder, does the immune system get suppressed when we are sleeping and why? During both these conditions ...
2
votes
0answers
37 views

How to gather life-history traits data on bird species?

I am looking for a data base of life history traits for bird species. Is there such data base? If not, what are your advice on how to collect those data? Is there a handy website that list ...
3
votes
1answer
16 views

Cellulose acetate membrane filters vs. glass microfiber filters

At equivalent pore sizes and pressures, which exhibits faster flow rates, cellulose acetate membranes or glass microfiber filters? I know cellulose acetate exhibits low protein binding, but what ...
4
votes
0answers
27 views

Understanding F-statistics in population genetics

I am reading a classical Weir and Cockerham 1984 paper about Fst estimation. At the beginning (first page, right column), they define 3 statistics. $F$ is the correlation of genes within individuals ...
1
vote
0answers
54 views

Do genetic modifications exist to enhance the taste of tomatoes?

GM tomatoes seem less tasty. Has there been any research on GMOs with regard to taste? Can scientists introduce a gene to, let's say, tomatoes, which would enhance the flavour? If not, why?
-2
votes
1answer
41 views

Why do aquatic animals smell so bad? [closed]

Many have experienced the "fishy" smell prevalent with seafood, but why do aquatic animals smell so bad? Is it because of salt water?
1
vote
1answer
33 views

Can Nanodiscs be used to study membrane energetics?

Nanodiscs have changed they way we can study the structures, insertion, and functions of transmembrane proteins. Below is an image of a nanodisc bilayer. The key difference, as far as I can tell, ...
6
votes
1answer
43 views

How does pressure measured by sphygmomanometer translate directly to blood pressure?

As per my understanding a sphygmomanometer when wrapped around the arm and inflated only measures the pressure of the air inside the cuff, doesn't it? How does that translate directly to the pressure ...
3
votes
1answer
60 views

Are there histones present in the cytoplasm?

In this paper the authors depleted core histone heterodimers H3-H4 at 90 % from the cytoplasm of Xenopus oocytes. They state that their concentration is in the order of 6 uM. My question is, are ...
3
votes
1answer
42 views

Is pulse rate measurable in the capillary bed and venous vasculature?

Pulse rate is easily felt when gently pressing the arteries in the wrist or neck region (Fig. 1). Fig. 1. Feeling the pulse at the radial artery. Source: Wikipedia Arteries supply the thin ...
-1
votes
1answer
26 views

Critical discussion: Gene expression and systems biology allows us to understand the control of complex traits

I'm having a bit of trouble tackling this question. Any help on what I should write about or the points I should mention would be much appreciated. I keep seeing articles about eQTL and QTL are these ...
12
votes
3answers
2k views

Help identify this worm-like thing

Many instances of this worm-like creature were found in a water system for a mountain cabin in the Sierra Nevada mountains of the US, in late June / early July. The water system collects water from ...
1
vote
1answer
20 views

Genetic linkage greater than 50 centimorgans

Classically, the linkage between two loci can be measured in centimorgans (cM), which represents the percent chance that these two loci will recombine an odd number of times (generating a recombinant ...
2
votes
0answers
23 views

Do animals commit suicide? [duplicate]

Do we have documented cases of animals purposely and consciously trying to end their own life? What leads to animal suicide, and is it preventable? I've heard mixed answers from various biologists. ...
-4
votes
1answer
77 views

How significant is the genetic component of homosexual behaviour?

From some basic googling, I found that nobody has ever proven that people are born gay and that environment plays a great part in homosexuality. I wish to know if there is a genetic component to ...
3
votes
1answer
50 views

Hodgin-Huxley model for a single neuron

I am viewing (through edX ) an introduction course to computational neuroscience. In the second lecture, the Hodgin-Huxley model is considered. I am going over some of the questions and have ...
10
votes
1answer
1k views

Why do chickens not try to get up if laid on their backs?

I've seen a few videos about chickens being laid on their backs for a few seconds after which the chickens stay in that position until they are turned over. Comments around the video suggested that ...
7
votes
1answer
127 views

Are there any theories why such an imbalance in chirality of molluscs?

Most gastropods exhibit sinistral (right hand) winding of their shells. But very few species are anti sinistral. Have there been any theories as to why such a great difference?
7
votes
1answer
49 views

Why do humans require vitamin B12 supplementation while herbivores do not?

This question came about from reading the comments of this (very unclear) question, which the author did not properly clarify. Vegans are often recommended to take vitamin B12 supplements, as the ...
0
votes
0answers
35 views

What is the reason our body stops producing collagen/elastin?

Stops producing elastin at around 14 years old. Collagen -- at 25-30. What is the reason?

15 30 50 per page