1
vote
0answers
12 views

Cis-AB phenotype verification

I know that my blood type is AB. I wanted to know if I am cis-AB since cis-AB seems to have a different approach in blood transfusion. Is there a lab test that can verify is a person is under cis-AB ...
9
votes
2answers
77 views

Cause of hexadactylisim in Amish people

Is it caused by inbreeding of many generations within an isolated population?
5
votes
1answer
56 views

Is there a karyotype database for human cell lines?

I'm looking for the karyotype of a specific cell line. Some karyotype are well known, such as HeLa or some carcinomas, but some are very hard to find, such as LG2 (B cells). Is there a database ...
0
votes
0answers
62 views

How to mimic / approach some animals/insects' anabolism?

This article states that some shelled animals - spiders, scorpions, crabs, worms and other creatures - have metal atoms in their claws, jaws and fangs. I believe through anabolism, since they eat ...
2
votes
1answer
36 views

Why would mutation rates increase in a tumour?

This article describes a tumour: Swanton found that even the primary tumour was surprisingly varied. He found 128 mutations among the various samples, but only a third of these were common to all ...
3
votes
3answers
68 views

Why is dopamine or a dopamine-receptor agonist not pumped into the brain of Parkinson patients?

I am aware that dopamine cannot cross the blood-brain barrier, but can't it be pumped inside the cerebrospinal fluid via some permanent tube implant? Wouldn't Parkinson patients chose that over ...
5
votes
2answers
53 views

Is viral protein expression important for peptide vaccine?

I would like to know if proteins expressed in higher quantities, such as DNA polymerase, would be better vaccine candidates for a T-cell based vaccine.
3
votes
2answers
37 views

Madrid, Noise by the river: Bird or cricket?

I currently live in Madrid, Spain. In July there was a loud animal near the river, in an out of town area surrounded by grassland, with trees along the river. It's continued into August, though it ...
1
vote
1answer
16 views

does phagocytosis dependent on opsonization?

does phagocytotic activity of macrophages and neutrophils depends on opsonization by IGg (antibody) and C3 complex,if it does, so then why macrophages and neutrophils are categorized in Innate immune ...
2
votes
1answer
39 views

If nerve consists of many axons, where are then their soma located?

This question has haunted me for two years. Wikipedia mentions : A nerve is an enclosed, cable-like bundle of axons (the long, slender projections of neurons) in the peripheral nervous system. ...
4
votes
1answer
50 views

Does tremor frequency generally increase as Parkinson's disease progresses?

I've been trying to research this question, but most if not all the on-line journals require costly subscription, and the studies that are posted look at tremor frequency with regards to other ...
8
votes
2answers
98 views

If Tumors have lots of mutations in them how is it the immune system can't detect them?

If a cancerous tumor has a lot of mutations in them why can't the immune system detect them? If a person has cancer could this somehow alter the person's immune system so it doesn't function ...
4
votes
1answer
231 views

Relationship between nerves and axons

I just wanted to get a realistic viewpoint of our nervous system. I understand arteries and veins, but I wanted to know how similar our nervous system is to that? I understand we have neurons ...
3
votes
1answer
32 views

Any examples of animal behavior in response to meteor showers?

I just spent two nights observing the Perseids and was wondering whether any animals have been recorded to exhibit unusual behaviour in response to meteor showers. It is known that some animals ...
0
votes
1answer
50 views

Drinking soda triggers tingling on a tiny spot on my upper back… but how? [closed]

The title pretty much says it all. Yes, I know it doesn't make sense. That's why I'm baffled. For the past week or two, I've noticed that drinking soda seems to cause a tingling/stinging sensation ...
7
votes
1answer
57 views

How do plants benefit from their seeds being buried?

Common planting advice, when starting many plants from seed, is to bury the seed some small distance under the soil. It seems like most plants (at least members of class Dicotyledonae) will grow a ...
2
votes
1answer
30 views

Do “virgin” ant queens ever shed their wings?

In species that reproduce sexually, if an ant queen goes on a nuptial flight and does not successfully mate, will she still shed her wings and try to found a colony (although she probably won't ...
1
vote
0answers
27 views

Can fingerprint patterns be changed using gene therapy?

Not to confuse with your "DNA fingerprint" I've read surgery is readily used to not just remove but even to change people's prints through employing very small grafts between opposing hands. About 5 ...
2
votes
1answer
27 views

Testing CO₂ for cell culture

I'm am refurbishing some old CO2 incubators. I would like to test the precision of the CO2 sensor. There is a sample port on this incubator. What sorts of methods are commonly used to measure CO2 in ...
6
votes
1answer
345 views

Is consuming proteins different vs. consuming amino-acids and how?

Yesterday I had a discussion with a friend. He said that consuming proteins and amino-acids is different. He said that those who grow muscles would agree on that. I wanted to argue against that ...
2
votes
1answer
28 views

Can stress-induced cortisol reduce diabetes type I?

Let us consider a patient with type 1 diabetes. I think it would be safe to say that diabetes is an autoimmune disease. Now let us suppose this patient comes under stress. As far as I know, cortisol ...
4
votes
2answers
144 views

Why are lions the only social cats?

We know that almost all cats are solitary. How did the Lions (Panthera leo) end up social animals? Do we have an explanatory evolutionary path describing how the Lions became social while the rest of ...
1
vote
2answers
37 views

Is it possible to merge the genomes of photosynthesizing and electron-transporting bacteria to make an electric cell?

I had an idea of making electric current from bacteria. There are some bacteria that can photosynthesize, and some others are capable of transmitting electrons through each other. Is it possible that ...
3
votes
1answer
38 views

How long does it take unused antibodies to clear the system?

Say you have the flu and a normal immune system. Now you're all better but your antibody level is still elevated. How long does it take for those antibody levels to go back to a base value?
2
votes
2answers
304 views

What is this black insect (wasp-like?) South America?

I live in the Pacific coast of South America. Seems to have two wings, like a wasp's. The "tail" is a bit bulky but is only connected to the rest of the body by a thin part. It's black overall. The ...
5
votes
1answer
87 views

Mouse Colony Software

I am looking for a good mouse colony census program that tracks the mice we have in the lab, breeding success of breeders, lineages, multiple user access, etc. Jackson labs has a program that does ...
23
votes
3answers
2k views

Which organism has the smallest genome length?

Which animal/plant/anything has smallest length genome?
3
votes
0answers
37 views

L-tryptophan in mammalian cell culture

Why must the concentration of L-tryptophan be kept to a relatively low level when culturing mammalian cells? It's an essential amino acid, so I cannot fathom why low concentrations as opposed to ...
2
votes
1answer
33 views

Bright green caterpillar with long white stripes, few hairs, no extensions, possibly Noctuidae

Our herbs had strange holes, and we found eight of these caterpillars to be the reason. They were mainly underneath the leafs and measured about 5 cm in length. We collected them from the herbs, put ...
5
votes
2answers
43 views

How many copies of a gene?

I am studying mathematical models of transcription and translation and I am wondering: In a particular genome, how many copies of a gene coding for one particular protein should one expect? Are they ...
1
vote
2answers
19 views

What are blood group determinants? [closed]

I am trying to understand if they are the same as the blood antigens. The books I have tried to read say something about them being the antigens on the surface of the red blood cell.
0
votes
2answers
61 views

Molecular graphics

anybody know of some great free molecular graphics systems that can allow for PDB code input? I prefer that it doesn't use Java. I also prefer that it is online, although if there is a great system ...
26
votes
4answers
18k views

How does cerebrospinal fluid circulate in the central nervous system?

Cerebrospinal fluid (CSF) is produced in the choroid plexus of the lateral ventricles and in the 4th ventricle of the brain. CSF then circulates through the ventricles of the brain and the ...
3
votes
1answer
41 views

Is sequencing error a function of the nucleotide being read?

Checking out on Google Scholar, I can see that for Illumina (just to consider one example) the sequencing error rate is of the order of 0.001-0.01 per nucleotide. Talking about sequencing error, ...
19
votes
1answer
5k views

What do you see when your eyes are closed?

If you are in pitch black and you close your eyes, you sometimes can see strange shapes of various colors. A lot of the time these shapes and colors change as you observe them. This phenomenon still ...
2
votes
1answer
21 views

How do catenanes form when DNA replicates?

So I am taking a course in DNA replication and repair. And we are talking about catenanes forming when DNA replicates (two circles of dsDNA interlinked) How is this possible?
0
votes
2answers
63 views

Binding of Multivalent Antibody to mutiple epitopes?

A multivalent antibody molecule such as Immunoglobulin M Immunoglobulin A etc bind to more than one antigens or epitopes but I am confused about that wheather these multivalent antibodies bind to ...
6
votes
2answers
179 views

Conjugate secondary antibody

Why is the secondary antibody conjugated to the enzyme in ELISA, instead of the primary antibody? Wouldn't it be easier to conjugate the enzyme to the primary antibody?
0
votes
0answers
32 views

Help with species identification

Could someone help with identification of this small mammal? Is it a possum? A dormouse? It was photographed in Sukhumi botanical garden, in Abkhazia.
4
votes
1answer
62 views

Fruit-bearing tree identification

Just moved into a new house in Puerto Rico and I found this tree in the back garden. Can anyone tell me what tree this is, and whether its fruit is edible?
3
votes
2answers
57 views

Why are our bodies created to itch when histamine is released by our immune systems?

Why do bug bites and cuts itch when scratching them clearly doesn't help us survive? Did our early ancestors need to rely on this itching sensation, or is it just that the receptors for itches just ...
2
votes
1answer
20 views

Is there a good site or software to see if a primer pair spans an exon junction?

I am going to perform some RT-qPCR tests to validate an experiment.  I'm currently in the process of ordering primers, and I would like to get them from the Harvard Primer Bank since these have been ...
1
vote
0answers
8 views

How are split inteins joined?

Do they form a peptide bond? Or is it just some affinity/van der Waals interaction? Is the mechanism enzyme catalized? Are the residues/moieties at the join site known? Could they be introduced to ...
0
votes
1answer
57 views

How much penicillinase is needed to deactivate 125mg of amoxicillin?

How much penicillinase is needed to deactivate 125mg of amoxicillin? Penicillinase in penase concentrate from CPC. 20,000 Levy Units/ml/min I need IU of 125 mg of amoxicillin. Please note that the ...
5
votes
2answers
94 views

Do variant callers miss rare variants in reference?

Generally variant calling programs (such as GATK-UnifiedGenotyper) look for differences between reference genome and submitted sequence. However, we all know that reference genome consist rare ...
4
votes
1answer
66 views

How many traits can a multivariate breeders equation handle?

The multivariate breeders equation (MBE) by Lande predicts the change in a trait $\Delta \bar z$ (response) as $\Delta \bar z = G \beta$ where $G$ is a genetic variance-covariance matrix and ...
4
votes
0answers
35 views

Variance in Fst in the infinite island model

The most famous result in the study of structured populations come from Sewall Wright. He showed that in an island model, where each subpopulation is of size $N$ and the migration rate is $m$, then ...
1
vote
1answer
31 views

How does the MET gene work and what happens when the promoter region gets mutated?

I am doing research on inherited risk of Autism Spectrum Disorders(ASD) due to common Copy Number Variants(CNVs) One of the mutations is the 'CC' variant of Rs1858830 in the promoter region of the MET ...
3
votes
5answers
3k views

Why do cell membranes have a lipid bilayer?

Many cells have a cell membrane composed of two layers of lipids, why is it two layers and not just one? What purpose do the membranes serve?
8
votes
1answer
16k views

What factors affect the rate of transpiration in plant leaves?

I'm trying to get my head around factors which affect transpiration in leaves. For example, how would applying petroleum jelly to the surface of plant leaves affect their rate of transpiration? I ...

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