3
votes
1answer
33 views

Looking for a gene in my raw genetic data. What are the possible causes for this?

Obviously, I barely know what I am talking about. But I want to find the "MUC5B promoter polymorphism rs35705950" in my RAW genetic data from 23andMe. (see this ...
2
votes
0answers
27 views

ECG of heart transplant patients

I am studying ECGs of heart transplant patients. The difficult thing is that there is so little available data publicly. I must apply for data in my universities. It would be also great if ...
3
votes
1answer
40 views

Why cytotoxic T cells don't kill dendritic cells when they present antigen?

When a cytotoxic T cell (CTL) recognizes a peptide presented in the MHC-1 of a dendritic cell (APC), why it doesn't kill this cell? I know that initially, in the lymph node, the T cell is ...
0
votes
1answer
27 views

why is heart failure treated as more critical than kidney failure?

The kidney filters blood whereas heart pumps the blood. Filtering blood is important. Therefor why is heart failure treated as more critical than kidney failure?
2
votes
2answers
115 views

Like other animals, why humans don't have species & breeds?

Like other animals, why don't humans have species & breeds ? Even my pet dog is one type of breed, but we (humans) lack breeds & species? What is the main reason?
1
vote
1answer
31 views

Are bees positively phototropic

One day I had found some bees have come around the light source like other positively photo tropic insects, I hadn't seen any bees coming over light before. I think bees are diurnal and they don't ...
3
votes
2answers
47 views

Any benefit to low dose radiation?

Is there any survival benefit in humans that can be obtained from chronic exposure to low dose radiation, or is any dose of radiation a potential harm? Has any research been done into this?
0
votes
2answers
46 views

Counting the number of hydrogen bonds of multiple PDB files

I've been trying to figure out a systematic way to count the number of hydrogen bonds for multiple PDB files. DSSP shows me the total number of hydrogen bonds when I make ...
0
votes
0answers
21 views

Quetiapine tolerance

I've researched quetiapine for quite some time now and I've found some references to tolerance, but nothing conclusive. My question is whether quetiapine use builds tolerance to the drug and if so, ...
0
votes
0answers
24 views

What's the max speed that humans could run? [duplicate]

Assuming humans could use all of their muscle strength at once, with no need of cooling or energy, how fast could we theoretically run?
0
votes
1answer
36 views

Why we do not use RNAi to control ebola?

As you know using RNAi we are able to prevent gene expression. so why we do not use it to stop viral genes expression?
1
vote
1answer
25 views

Testing monophyly from per site log-likelihoods without optimising branch lengths

How can I obtain per site log-likelihoods for a topology against an alignment without optimising branch lengths? (which software can I use to do this) Per site log-likelihoods can be used for various ...
1
vote
1answer
53 views

Why do people and animals stretch out their bodies and what is causing this behaviour?

I noticed that my cat which is only 6 months old has started stretching its body from time to time. Then I thought that this motion doesn't seem very natural from another cat's viewpoint, so my cat ...
1
vote
1answer
38 views

Does methanol fixation deform cultured cells?

I use methanol fixation (@ -20⁰C for 10 minutes) when performing immunofluorescence assays on cultured cells. Generally speaking, this results in very good antibody staining. However, the cells tend ...
4
votes
0answers
34 views

What are parental antagonism & parental conflict?

I've been reading the chapter by Haig et al in The Genetics and Biology of Sexual Conflict. I think this chapter has them quite unclearly defined. Could anyone describe these two phenomenon more ...
1
vote
1answer
31 views

Why do humans have irregular teeth and impacting wisdom teeth?

Imagine that horses, dogs, bears, and gorillas had teeth as unreliable as humans do, The interruption in behaviour and stress brought by teeth would cause them to be more prone to sinus infections, ...
2
votes
0answers
38 views

Time for rigor mortis to set in [closed]

Rigor mortis sets in due to non-functional "ATP powered calcium pumps" as a result of which the calcium ions stream out & the muscles remain in a suspended animation state. But, it's a frequent ...
2
votes
1answer
121 views

Is excessive hydration a risk factor for cancer in humans?

I was reading a book on radiation biology, and the book describes the process of "indirect action", where radiation can first ionize a water molecule forming a free radical, which then may interact ...
2
votes
1answer
33 views

Alternatives to commercially available flow cytometric analysis software for use in cell cycle analysis?

I know that many labs use either FlowJo or FCS Express to plot and analyze their flow data. These seem like the two standards for most labs (and I have used FlowJo before). However, my current funding ...
2
votes
2answers
105 views

What is possibly wrong in my gel electrophoresis when I didn't see bands of DNA ladder on gel? [closed]

What was possibly wrong in my gel electrophoresis when I didn't see bands of DNA ladder, and genomic DNA sample on gel ? I could see bands of genomic PCR and RNA solution. Edit Thank you all of guys ...
0
votes
1answer
40 views

What is the chance that insects derive from extraterrestrial organisms? [closed]

I have long had the idea, and I think I've also hear it on TV, that insects could be descendants from organisms arriving Earth with meteors. The inside difference between insects and other animals is ...
0
votes
1answer
39 views

Why does dogs chase cats? [closed]

This seems a little weird to me.....Cat normally does not fit into a dog's food list....So why this peculiar, energy-wasting behaviour???
1
vote
1answer
37 views

What are some difficulties animals had to overcome to reproduce on land?

This is for AP Biology, but the assigned textbook chapter doesn't contain any information about the question. What are some difficulties animals had to overcome to reproduce on land? Some ...
0
votes
1answer
31 views

Safe level of chlorine in water [closed]

Chlorine is usually mixed in water to make it safe for consumption. What is a safe quantity of chlorine that can be consumed? What are the side effects of chlorine and does this include hair loss? ...
1
vote
1answer
24 views

Incestual Reproduction in Animals

I'm quite curious on how animals view incestual pairings. Given there are enough mates around, i have quite observed that most females (subjects are dogs, cats, pigeons and chickens) would go choose ...
1
vote
0answers
28 views

What triggers the formation of biofilm? [closed]

How does a bacterial biofilm form? In general, not specific to a certain industry or type of surface. I know how it forms; I understand reversible attachment, irreversible attachment, growth, ...
1
vote
1answer
23 views

The suspended cat clavicle

I know the clavicle of the cat floats freely as opposed to be attached as in humans. This is supposed to allow them to be able to squeeze through spaces, according to a quick google search. But how ...
2
votes
1answer
28 views

Which virus capsids consist of only one type of capsid protein?

The Tobacco Mosaic Virus (TMV) capsid consists of many copies of one protein (http://www.rcsb.org/pdb/101/motm.do?momID=109). Which other viral capsids consist of only one kind of coat protein? Does ...
9
votes
5answers
1k views

Do human cells contain only one copy of the genome?

Does each cell contain only a single copy of its genome? Or are there ever 'extra' copies present. Reason behind question: Wondering whether gene mutations could be corrected by referencing a ...
3
votes
1answer
36 views

Why did many odd-toed ungulates become extinct?

There were a lot of odd-toed ungulate animals in the ancient times but now just few of them survived. What is the reason for that?
2
votes
2answers
30 views

Does prolonged exposure to low pitch but low volume noise affect hearing or stress?

This is similar to another post but not quite the same... At work, our ventilation system produces a constant low pitched sound - like a rumble - as well as the sound of air blowing through the vents. ...
1
vote
2answers
22 views

During bridge amplification of DNA sequences, why aren't sequences amplified in both orientations?

During bridge amplification, when sequences attached to adapters on the surface form "bridges" and are replicated, it seems like sequences with either end attached to the surface will be created. For ...
1
vote
0answers
19 views

How to define the four haematological subgroup? [closed]

There are four main haematological subgroups, cross-reactive material-positive (crm+), cross-reactive material-negative (crm-), crm-reduced (crmR) and inhibitor patients. But what kind of substance ...
1
vote
1answer
21 views

Does the Peptide bond produce water in our organism?

According to Wikipedia http://en.wikipedia.org/wiki/Peptide_bond , when a peptide bond is made a water molecule is released as a secondary product. So, my question is simple (perhaps silly). ...
0
votes
1answer
52 views

Calculating number of amino acids in mRNA

Assuming there were 20 different amino acids and less than 40 types of different tRNAs found in this alien organism. How many amino acids would be found in the translational product of a ...
4
votes
1answer
42 views

Effect of recombination on the rate of loss of genetic variation

Following up from this question: Does recombination increase the additive genetic variance for fitness? (I'm thinking about the evolution of additive genetic variance and differences between the sex ...
4
votes
1answer
47 views

Publicly available resources for learning metagenomics

We are starting a metagenomics project in our research group to study microbiota in the respiratory tract. Since the are no books yet about metagenomics, seems reading some reviews and online ...
0
votes
1answer
27 views

Human longevity interventions ranked by effectiveness [closed]

Generally living longer and with a better quality of life is considered a good thing, if not for ourselves then for our family and friends who care about us. Some factors that influence human ...
1
vote
0answers
45 views

How did birds survive the KT impact?

As I understand it, the ejecta resulting from the K-T impact (also known as the end-Cretaceous or Cretaceous-Tertiary extinction event) re-entered the atmosphere all over the world; the heat from ...
7
votes
6answers
3k views

What is the use of eye banks, if eyeball transplants do not exist at present?

Corneas are donated and transplanted, but not the eyeball. I don't understand. What is the purpose of donating a cornea without an eyeball to a blind person?
1
vote
0answers
12 views

small RNA bioanalyzer traces showing miRNA enrichment for sRNA-seq

I am bioinformatician trying to support some small RNA-seq experiments. All bioanalyzer traces that I have seen for RNA at the small RNA range show at peak at 22. But probably it depends on the ...
1
vote
0answers
8 views

Predictive Single Nucleotide Polymorphisms (SNPs) for Bipolar Disorder

Are there any validated SNPs that are either predictive of developing bipolar spectrum disorder or are associated with its pathophysiology?
7
votes
2answers
351 views

Can we determine a person's age by dating methods or other means?

There are many sports restricted to players of a certain age (e.g. 16 and under, 18 and under, etc.) What if a person is older and fakes his birth certificate to say that he is younger? Is there any ...
1
vote
1answer
31 views

Why are there no marine birds?

Walking by the lake and watching the ducks the other day a thought struck me; there are lots of aquatic birds but all remain at least somewhat terrestrial, nesting on land. Why is it that no birds ...
0
votes
2answers
46 views

Are Purkinje Action Potentials Neuronal and Cardiac?

I first thought that action potentials of His-bundle i.e. Purkinje fibers are Cardiac. However, I started to think that this is not enough. I think now that they are neuronal and cardiac. My ...
5
votes
2answers
45 views

How to identify genes required for biofilm formation

This is just a homework question: Q: Let’s assume that there is an unknown set of E. coli genes that are required for biofilm formation. Describe a genetic experiment you could perform to try to ...
2
votes
0answers
29 views

What is the biological basis of “energy” that extraverted humans draw from social engagements and introverts expend?

This question is related to this question about introverts becoming exhausted after extended social events on cognitive sciences stack exchange. As I read more on the topic of human ...
7
votes
2answers
1k views

Can human organs be transplanted indefinitely?

I watched this movie, where they rented hearts to people for a year. I wonder if it is possible to transplant a heart indefinitely from person to person, or does the heart have a lifetime? So, do ...
1
vote
2answers
28 views

C.elegans and antioxidants

How would you test the effect of antioxidants on C.elegans lifespan? Is this done through feeding E.coli with antioxidants and then C.elegans with E.coli, or is there another method?
3
votes
1answer
27 views

At which temperature is the Tick-Borne Encephalitis Virus destroyed?

At which temperature is the Tick-Borne Encephalitis Virus destroyed? If there is no data specifically for TBEV, is there any data for typical temperatures at which other Flaviviruses / Flaviviridae / ...

15 30 50 per page