1
vote
2answers
39 views

Are there tools for automatically parsing glycan names into tree structures?

My colleague and I are working on a project involving data produced at a glycan microarray facility. The array data that came back to us were a list of glycan names (in IUPAC condensed format). We ...
3
votes
1answer
19 views

Functioning of BCG vaccine

I read (from Nature Volume507, S4–S7 (06 March 2014) : For reasons that are poorly understood, BCG protects only infants; it is ineffective in older children and adults. Its efficacy also ...
-1
votes
1answer
44 views

What is the blood ejection speed outward from human body vein? [closed]

At what height blood can eject from human vein ? I see, sometime there is direct blood transfer from one person to patient. So sometime blood bottle is kept at certain height and blood is transfer ...
1
vote
0answers
44 views

How do cellphones calculate heart rate?

How do cellphones calculate heart rate ? I understand that the cameras there try to count undulation in blood flow, but is the method of calculation same as that of professional SpO2 monitors ?
-4
votes
1answer
34 views

What is the division of lymphatic system in this picture?

I am trying to understand this schematic figure. I do not understand Latvian so I have to think what they mean by the words krusu, aiznesosais and pienesosais. I think they mean something like ...
1
vote
0answers
27 views

How did the roar evolve from snort?

When Lions roar, or Dogs show aggression, they do that snort-roar thing. They're producing sound while inhaling. How did that come to be when all (?) other forms of sound involve exhaling? Humans do ...
3
votes
0answers
40 views

Data analysis of transcriptome sequencing data

I want to learn more about the data analysis and statistics on transcriptome sequencing data. I would like to read some important papers of the field and books and maybe some MOOCS, if they are ...
1
vote
1answer
55 views

Difference between inbreeding and interbreeding

Is inbreeding the same as interbreeding? On this site interbreeding is defined as (http://www.thefreedictionary.com/interbreeding): To breed with another kind or species; hybridize. To breed ...
1
vote
0answers
13 views

Evolutionary rationale behind migration proteins

Tumor cells are able to migrate due to specific migration proteins. What is their evolutionary origin? Or are they simply deregulated?
1
vote
1answer
27 views

NaCl role in CTAB - DNA complex in DNA extraction

I have a question about the role of NaCl in the DNA extraction process. So for NaCl concentrations under 0.5M, CTAB and DNA molecules can create complexes. In those concentrations, proteins and other ...
2
votes
3answers
70 views

How quickly is antibiotic resistance lost?

I would imagine the bacterial genome is highly conserved and limited in its space, but maybe I am wrong. If you were to take a strain of antibiotic resistant bacteria and kept them isolated, but fed ...
0
votes
1answer
28 views

What is the difference between fibrogenesis and fibrosis?

Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. I used the word "fibrogenesis" as the outcome of acute inflammation (healing). ...
2
votes
0answers
21 views

Gibson assembly using NeBuilder

I am supposed to construct a plasmid that contains features from two other plasmids. My strategy is to generate three fragments form the two other plasmids. I was encouraged to try Gibson assembly, ...
2
votes
2answers
36 views

Functioning of BRCA2

I know that BRCA2 interacts with RAD51 to repair DNA damage. But how exactly does it function ? What are the other proteins that interact with it ?
5
votes
1answer
52 views

Can a carnivorous animal consume plants with no adverse effects?

While I know that in nature, carnivorous animals are poorly suited to eat plants (largely due to having sharp teeth, not grinding teeth, as far as I know), I was wondering if, in an emergency ...
0
votes
0answers
6 views

Can pulmonary infarction be asymptomatic?

I think it can because there are many parts in lungs. Like for some COPD patients. However, I am not sure if COPD patients can have infarction. Lungs have parallel circulation. Red infarct is ...
0
votes
0answers
16 views

The distance the electromagnetic field of the heart can be detected

A very smart friend of mine seems to get taken in by junk science. He started telling me last night that the electromagnetic field of the heart can be detected beyond 30 feet. What is the actual ...
2
votes
2answers
17 views

pI and pH relationship in context of ion exchange protein purification

I am confused about relationship between isoelectric point and pH in context of ion exchange protein purification. Why we cannot use this method for protein with pI below 7? Thank you very much for ...
0
votes
1answer
13 views

Association of shorter telomeres with heart disease

From this paper Those with shorter telomeres in blood DNA had poorer survival, attributable in part to a 3.18-fold higher mortality rate from heart disease (95% CI 1(.)36-7.45, p=0.0079), and ...
0
votes
0answers
11 views

Respiratory protections against various pollutants

Obviously it's better than nothing, I live in a city, less polluted than the leaders like Hanoï, Shangai, etc.., but strangely, I already expressed it on this site, I have a sort of disproportionate ...
4
votes
1answer
57 views

Sexual Differentiation in Monoecious plants with unisexual flowers

In monoecious plants having unisexual flowers (eg Zea Mays, Ricinus Communis etc), there must be some mechanism as to produce two sexually distinct flowers from the same genotype. Since both the type ...
1
vote
0answers
25 views

Three great discoveries of modern science according to Gould? [closed]

What is the third of "the three great discoveries" of modern science, according to Stephen Jay Gould? Any citation from one of his books? I know the first two are the vastness of space and the depth ...
1
vote
1answer
54 views

What is this plant?

I really like this plant--I'm just wondering what its name is (perhaps genus+species). I think this plant grows in the tropical rainforest in Malaysia. Any suggestions? Thanks!
1
vote
0answers
21 views

Where people age at slower pace - mountain or seashore [closed]

where people live longer - mountain or seashore? If mountain then at what elvation they age at a slower pace?
0
votes
1answer
19 views

Why violets die in closed space?

I'm going to engage into making florariums (a garden in the bottle). I've heard, that violets die in closed space. Do anyone have an idea, what is the reason for that? Lack of oxygen or CO2 or ...
1
vote
1answer
33 views

Can a fungus become resistant to a chemical such as Potassium Permanganate?

A friend used potassium permanganate solution to treat tinea on the hands/feet but after some initial success, the tinea seems to be making a comeback. Could the fungus develop resistance to potassium ...
3
votes
1answer
39 views

How can I re-format my DNA motifs' position weight matrices?

I am working with a set of DNA motifs that are predicted as potential regulatory motifs (e.g. transcription factor binding sites). The motifs belong to several species, and I wanted to cluster these ...
0
votes
1answer
25 views

Real time PCR result interpretation

i performed a real time PCR. I was looking for expression fold changes for 2 genes and i had two sample pools, one treated and the other not treated (for each gene). The problem is that my ...
0
votes
0answers
12 views

book on genealogy, haplogroups, migrations, etc

Looking for a popular science book on the topic. I need a wide-angle expose, not fiddling with minor details. It should also be somehow intertwined with migration. I've recently learned, for example, ...
0
votes
1answer
19 views

Pathogenesis of Chronic Venous Congestion in Lungs?

I am thinking how CVC in lungs lead to the left-sided heart failure.
2
votes
1answer
69 views

What insect is this..?

Can anyone tell me what kind of insect (if it is one) is this...!! Or is it the pupa of some insect? Well I don't think that the whole big thing is the insect itself, it appears to be just a kind of ...
0
votes
0answers
11 views

What is the patogenetic mechanism of brown pigment lipofuscin in muscle atrophy?

I think it is autophagy. Lysosomal degradation. Autophagocytosis. Example of the brown pigment (lipofuscin) here: I am not sure if autophagy is the right answer to the "patogenetic" mechanism of ...
0
votes
1answer
27 views

Pathogenesis of chronic venous congestion in skin?

I think CVC cannot lead to heart failure primarily. So let's think its pathogenesis in skin now only. I think the pathogenesis is like this dilation of veins and capillaries due to impaired venous ...
0
votes
0answers
5 views

Can systemic intravascular thrombosis cause brain infarction?

I wonder if the thrombus can pass through the brain-blood barrier because I think small molecules like O2, CO2 and ethanol can pass it. Probably, in some diseases where the permeability of the barrier ...
0
votes
1answer
27 views

Dimensional analysis Question

So I'm new to the dimensional analysis world and I'm little confused and the answers I'm getting are not convincing :( if the concentration of hemoglobin in a 5ml sample of blood is 34 g/dL. and red ...
0
votes
1answer
41 views

How does DNA mess up

When there is an error in copying DNA (a mutation), what exactly goes wrong? If G goes with C and A goes with T, I don't see how that part can mess up. Is the idea that when the double helix is ...
3
votes
1answer
30 views

Hela live cell confocal laser scanning - reccommendations for good fluorophore that will show good movement

I've been doing a lot of live cell imaging lately mostly using hela cells expressing some EYFP based chimeric proteins. I'm building a video library for an art student here at the university who is ...
0
votes
0answers
7 views

Is this dystrophic calcinosis in anthracis?

Coalworker's pneumoconiosis with multifoci: There are macrophages filled with dust (exogenous accumulations). I am thinking if there is happening a cellular adaptation (dystrophic calcinosis) to ...
1
vote
2answers
97 views

How much of your stock solution should you take to make the 1000 cells/mL mixture? [closed]

You need a solution containing 1000 buccal cells/mL. You count that you have 125 buccal cells in 50uL, from a total solution of 8 mL. How much of your stock solution should you take to make the 1000 ...
1
vote
1answer
7 views

Which inflammatory response with Cytomegalovirus infection?

I am thinking about inflammation process with Cytomegalovirus infection. I first thought it is about chronic inflammation, but then changed my mind because of virus infection. I think cytokines must ...
1
vote
0answers
17 views

Neuroscience: zapping an axon connected to thermoreceptor

Let’s say an experimenter has an electrode that can give a shock to a single axon. She takes that electrode and zaps an axon connected to thermoreceptors in the hand of her subject. I) What would the ...
0
votes
0answers
19 views

spinal cord lesion and result in somatic sensation

Jimbo suffers a lesion to the entire right half of the spinal cord at the T6 level. A few weeks after his injury, his doctor tests his right and left legs for somatic sensation and tone. fill out her ...
2
votes
1answer
26 views

What stops telomerase?

The telomerase is an enzyme that adds telomeres. What stops the telomerase from adding too many telomere sequences ? What's the regulating mechanism ?
1
vote
1answer
16 views

2 types of telomerases?

As telomerase works by adding new nucleotides complementary to the RNA it contains, it cannot work for the complementary strand. Say telomerase X has RNA complementary to the 5' to 3' strand it ...
4
votes
1answer
23 views

Telomerase in tetrahymena

In this amazing video, at 26:03 we see this image We now know that the telomerase contains a sequence complementary to the telomere sequence and so is able to do what it is capable of doing in this ...
1
vote
2answers
56 views

Conserved proteins are non immunogenic

I read that proteins that have been highly conserved are non-immunogenic. Why is it so ? What is the special thing that makes it non immunogenic(antibodies against them are hard to make) ?
2
votes
1answer
17 views

Meaning of the word Oleracea

What does "oleracea", as appears in numerous plant species (scientific) names, mean? Examples: Euterpa oleracea, Brassica oleracea, Portulaca oleracea, Acmella oleracea, Spilanthes oleracea.
2
votes
0answers
29 views

College Bio Research: Bacteria found on computer keyboards. [closed]

I am a college students brainstorming ideas on different topics that may be appropriate for on-campus research. What I came up with and I would like to give it a try is analyze the different types of ...
4
votes
0answers
37 views

Effective population size and overlapping generations

From this book; If generations overlap, then the effective population size $N_e$ does not equal the population size $N$. I know mathematical formulations in order to find the effective population ...
3
votes
1answer
33 views

Effective population size when the population sizes varies from season to season

Let's think of a species which has four generations per year and which population size changes from season to season so that the population size is 100 in summer, 200 in spring, 50 in autumn and 20 in ...

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