3
votes
1answer
104 views

Feeling of spicy

I have done a survey on my friend When everytime they eat something spicy, They will eat ice or drink icy water. First, Mostly they feel nothing but a cool sensation. However when they finished, they ...
0
votes
1answer
68 views

Why Insect bites are itchy rather than pain? [closed]

i don't understand if some thing bites or hurt we feel pain, but its differ for insect bites, why so?
0
votes
1answer
122 views

Using Jpred to predict secondary structure

I'm trying to use Jpred to predict secondary structure for a protein sequence. When I run J-pred, I get a bunch of hits from PDB. I've also noticed these 'hits' are the same name as the templates i ...
7
votes
1answer
139 views

Chromosome picture, how to interpret?

In this guide i was reading for annotations, there is a diagram of chromosomes of D.mel, I am confused as to why the chromosomes are all attached to one another, is this picture taken in a certain ...
3
votes
4answers
210 views

Recommend good conversational books to learn about cell and developmental biology or biochemisty?

I'm an engineer by training and teaching myself the basics of cell and developmental biology. I'm using Scott F. Gilbert's Developmental Biology and Alberts' Essential Cell Biology right now, and they ...
5
votes
1answer
75 views

Evolution of dominance of alleles

Can someone tell me where can I find detailed text about mechanisms of evolution of dominance? Or, if it is possible, I would be grateful if someone will tell me about them here.
6
votes
2answers
612 views

The effect on the efficacy and potency of a non-competetive antagonist binding to the active site of the receptor (dose-response curve)

According to the book "Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy" by Golan et al, non-competetive antagonists can bind to both the allosteric site and the active site. I ...
1
vote
1answer
185 views

Identify chromosome location from gene nucleotide or amino acid number

I'm sure this is a basic question, but I couldn't find an answer anywhere. Let's say I'm provided with the location of an amino acid or a nucleotide (for example, which lists the location as the ACADM ...
0
votes
1answer
89 views

Why in acute phorpyria? [closed]

I am having confusing about treatment of phorpyria . I read it somewhere that for treating phopyria hemin and glucose is given IV . Please give me an easy explanation of it
0
votes
1answer
43 views

One Gene and many proteins [closed]

Imagine a gene with $n$ exons and $m$ introns. How many proteins are possible from that gene? Would all the proteins be isoforms?
0
votes
0answers
37 views

minimum ratio of the shortest isoform to the longest one derived from one same parent gene

I want to know what is the minimum percentage of the shortest isoform/transcript to the longest one that derived from the same parent gene? Does it have organism specificity? What is the function of ...
7
votes
1answer
498 views

Extracting cell-free DNA

Has anybody had any success in extracting cell free DNA from plasma without using expensive kits? I've already spent a lot of my own blood trying to use standard phenol/chloroform methods with very ...
0
votes
1answer
52 views

Similarity between the human genome and archea genome in deep sea hydrothermal vents?

I'm trying to find some reference that shows what percentage of the human genome is similar to some organism from the domain Archea that lives near or on deep sea hydrothermal vents. Can someone ...
2
votes
1answer
534 views

What happens when we stretch?

From the wikipedia page on stretching: Stretching is a form of physical exercise in which a specific muscle or tendon (or muscle group) is deliberately flexed or stretched in order to improve the ...
5
votes
1answer
115 views

Do any birds have established “poke a predator's eyes out” behavior?

Is there a pattern/tactics of behavior in any birds species that consists of attacking a predator's eyes with its beak? I'm looking for established tactics, not 1 or 2 anecdotal examples.
4
votes
1answer
103 views

Bayes theorem for mutations

MEN 2A is a dominant inherited disease caused by a mutation in the RET proto-oncogene. The probability of being sick when you have the mutation of the RET proto-oncogene varies with age and is assumed ...
3
votes
1answer
1k views

D/L configuration for amino acids

Why would this be "L-cysteine"? This is taken from the answer key for my biochem final. From what I understand if the -NH3(+) is on the left then the alpha-amino acid is in the L-configuration. ...
0
votes
1answer
122 views

Mutations/deletions with CRISPR

I need to stop some protein from being active and searching for some universal way to do so. In mammalians. With CRISPR it is possible to knock-out the entire gene. But it's a little complicate ...
0
votes
1answer
96 views

Finding Rna-Seq dataset for C. Elegans (Caenorhabditis elegans)

I want to find a RNA-Seq dataset for C. Elegans to use it in RNA-Skim software. For those who does not know RNA-Skim let me explain it a bit. It is a tool which is used to quantify RNA-Seq data using ...
4
votes
1answer
96 views

How can a heart of human work if one of its valve is not working?

Yesterday I went to a hospital and heard a doctor say that one of the heart valves of a patient is not working. However, the patient was still alive and was healthy; the patient could walk and talk ...
3
votes
1answer
143 views

Any evolutionary explanation for human blood groups?

What is the explanation of people having blood types from an evolutionary perspective?
2
votes
1answer
75 views

How is protein cavity centre related to binding?

I am confused and I have the following questions: 1. What are (in the context of article below) protein cavity centres? 2. How are they related to binding? (Automated identification of protein-ligand ...
1
vote
0answers
52 views

Would it be possible to create a gel, holding viruses, that could alter the human genome when rubbed in?

I was wondering if it could be possible to engineer a virus, that when it comes into contact with human hair follicles, it could alter someones natural hair color. Naturally blue hair anyone? ...
6
votes
3answers
492 views

Is homosexuality an adaptation in humans?

Homo sapiens have menopause - as some other mammals (e.g. some Cetacea) - a phenomenon where older females live for decades after the end of their own reproduction. Perhaps homosexuality, that looks ...
0
votes
1answer
48 views

Can a relationship exist that is mutualistic/parasitic/etc. but not considered symbiotic?

Wikipedia definition of symbiosis: "Symbiosis (from Greek σύν "together" and βίωσις "living")[2] is close and often long-term interaction between two or more different biological species." Wikipedia ...
0
votes
2answers
2k views

Why is my peripheral vision better for seeing in the dark? [duplicate]

I often walk around my house at night with the lights turned off and one night I noticed that looking straight at an object with very little light available made the object disappear from sight but if ...
0
votes
1answer
58 views

Synteny, genetics?

Could anyone explain the concept of Synteny relating to genetics? A picture would help. I tried read the wikipedia source along with another PDF ...
1
vote
0answers
100 views

Why is chemotherapy so expensive? [closed]

I have two questions related to the price of chemotherapy: I was told it was expensive, but was not able to put numbers on it. Where could I find information regarding the actual price of a given ...
3
votes
2answers
67 views

Determining how much energy a plant takes in?

I asked a question on WorldBuilding.SE, "Are diamond berries possible?". This led to asking a question on Chemistry.SE about the amount of energy required to burn a 1 ct. diamond (−6.527kJ). The ...
5
votes
1answer
137 views

Is it possible to express a mutant gene only in a specific tissue?

Imagine that someone tries to develop a knockout mouse for a gene, but this result in lethality for the homozygous. Is it possible to express that mutant gene only in a specific tissue of interest to ...
11
votes
2answers
454 views

Can we make a rough estimate of the number of generations since the origin of life?

According to what we've learnt : we can approximate the number of generations since the first human pretty much like us (depending what / who we talk about). we have an idea of the series of life ...
2
votes
1answer
61 views

Identification of a larva

Last week-end I was working in my parent's garden and when I dig a bit the ground, I found few larvas I never seen before. My father told me there are there every time when he's doing the garden ...
6
votes
1answer
222 views

During the process of correcting mutations via gene therapy, is the defective gene removed?

Just recently started learning about gene therapy, many websites explain that the corrected DNA can be added to the genome using a vector and all that. I just don't understand what happens to the ...
3
votes
1answer
77 views

Identification of a plant (in a pot)

I have in my flat a plant which sometime make strange flowers. When the start it looks like plastic stars: Then the flowers are opening after few days and looks like this: The smell is a bit ...
1
vote
1answer
92 views

What is the developmental basis of the placental sac?

The placental sac is the organ that provides nutrients to the embryo from the mother. My question is that, since this obviously involves a lot of complexity, where does the sac originate from ...
0
votes
1answer
112 views

Advantages of gregarious vs solitary behaviour?

I'm trying to explain why birds (specifically wildfowl) are gregarious during the winter and solitary during the summer. I think that in winter, birds are gregarious to reduce the risk of predation ...
3
votes
0answers
30 views

Generate T2/T1 Phage Resistant E Coli

I would like to generate T2/T1 phage resistant Stbl3 E Coli to use in virus production. Is there a plasmid somebody has used that confers resistance, or is this done another way?
3
votes
0answers
139 views

From where is the pollen kit material secreted?

From where is the pollen kit material secreted? I think it the tapetum would be a good candidate, since it is provides nutrition to the pollen grains.
1
vote
2answers
31 views

Difference between taking tissue of cancer from secondary place or primary place

Are there any differences when a surgeon takes tissue from secondary place (for example from metastasis) rather then from primary place (from an organ where cancer is) for morphological research?
2
votes
1answer
48 views

Where does the exudate comes from during inflammation?

During inflammation transudate and exudate is formed by vessels. I would like to make sure if it comes from arterioles, venules, or both, and the reason why.
6
votes
2answers
160 views

Do we have fundamental conflict in biology?

As saying "fundamental conflict", I mean something like two (or more) widely accepted results from different areas (or scales) can not exist logically together. In physics, there have been three ...
0
votes
1answer
39 views

What is contiguous premise culling and dangerous contact culling?

I am reading this paper related to FMD (foot and mouth disease) epidemics which occurred in UK. It mentioned about terms like IP (infected premise culling), CP (contiguous premise) and DC (dangerous ...
5
votes
1answer
120 views

Can we produce synthetic red blood cells lacking antigens?

I had an idea come to me during Biology class and I immediately asked my teacher, but she couldn't really answer the question, so I'll ask it here. What are the limiting factors in the production of ...
0
votes
1answer
262 views

GPCRs: Gi and Gs

GPCR = G-protein coupled receptor Gi = G inhibitory alpha subunit Gs = G stimulatory alpha subunit Are there structural differences between Gi and Gs subunits (secondary structure)? Or is it just ...
2
votes
1answer
195 views

Recessive alleles at Hardy-Weinberg equilibrium

I've run into a question that I disagree with others on but I would like to receive the input of others. The question is: If a population is at Hardy-Weinberg equilibrium, which of the following can ...
5
votes
1answer
161 views

Do human-ape hybrids exist?

Since humans and apes share up to 99% of their DNA, can they interbreed? For example, a horse and a donkey seem to be just as distantly related and produce offspring. Mules, however, are sterile. ...
3
votes
1answer
57 views

Why do genes with closely related functions often reside on different chromosomes?

Why do genes with closely related products are so often positioned on different chromosomes? To illustrate what I mean, here is an example from immunology: the invariant region of MHC is on ...
3
votes
2answers
306 views

Before I move my arm the brain sends signals - what causes the brain to send signals? [closed]

Please tell me what causes the brain to send signals, how does the brain send signals? can you tell me what happens between the point when you make an intention to pick up a glass of water, and ...
5
votes
2answers
386 views

Specificity of the immune system

We know that the adaptive immune system recognizes foreign particles when their proteins are expessed of the the surface of T-cells, complexed with MHCs. But MHCs present only short peptides of length ...
5
votes
1answer
385 views

Does crude oil or kerogen contain ancient DNA?

According to wikipedia by the formation of oil there are a lot of organic materials present including DNA. Is it possible that this DNA is conserved somehow for millions of years?

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