0
votes
1answer
18 views

Is nutrient absorption different in Hypersensitive I patients?

I am thinking how the nutrient absorption differs between between patients with allergies (Hypersensitivity I) and those not. The current guideline about number of eggs in diet is one daily ...
1
vote
1answer
35 views

Function and process of TCTE-1 receptor

I was wondering if anybody knew of the function and process of the TCTE-1 receptor during the binding of a sperm with an egg. The only think I know of TCTE-1 is that it is a species-specific receptor. ...
1
vote
1answer
34 views

Significance of prostaglandins in semen?

I am trying to figure out how prostaglandins in the semen relate to the female reproductive tract. More specifically, How does prostaglandins in semen help the female reproductive tract increase the ...
0
votes
1answer
131 views

What is the function of clot retraction?

I am thinking how clot retraction and fibrinolysis work together. I think that clot retraction is a process that gets clot towards fibrinolysis process. Fibrinolysis process then lyses the clot. ...
1
vote
1answer
28 views

Could mating/recombination be responsible for evolution of entirely novel features?

The diploid chromosomal architecture is rather interesting. For example, because of diploidy we Humans have to mate. Of course in that sense, because diploid organisms often have mate, this has led to ...
2
votes
2answers
513 views

How did the first sexual animal come to exist? [closed]

I am more or less familiar with the evolution theory based on mutations. Now, starting with a nonsexual being, how did the first organism that reproduces sexually come to exist.
2
votes
1answer
30 views

How do beneficial features evolve in species without progressing through detrimental stages?

I'm thinking in particular of wings on birds that would - I'm guessing - have to progress through stages during which they confer no particular advantage. Or is it that all evolved features must have ...
4
votes
1answer
906 views

How do I calculate the change in allele frequency in a haploid population under selection?

From this book For simplicity, let us consider a haploid organism and assume that the frequencies of alleles $A_1$ and $A_2$ are given by $x$ and $y=1-x$, respectively. We also assume that the ...
2
votes
1answer
34 views

Transport of mammalian insulin in vivo

What is the mechanism for transport of insulin in mammalian cells?
5
votes
1answer
2k views

What's the minimum distance of focus for the lens of a human eye to reach maximum flatness?

According to the Wikipedia article on eye accomodation, the range in which a human eye can focus is from 7 centimetres away up to essentially an infinite distance. Of course, people can't see things ...
2
votes
1answer
38 views

Activity of glucokinase

From Solomon et al, 2013 ACC Synthetic biology and from this video : Here, there are 2 competing reactions for glucose - one with glk as enzyme and other with gdh as enzyme. In the graph, y axis ...
2
votes
1answer
123 views

how do they identify different protein chains?

Can someone please explain how different protein chains occur exactly? I'm not talking about the side chain, but the protein chain which is typically labelled as A,B,C etc in the PDB. I'm curious as ...
4
votes
1answer
63 views

Can P. falciparum and other malaria parasites be cultured and genetically engineered?

I'm not a parasitologist, and I was wondering about the current state of malaria research. For instance, is it possible to culture P. falciparum? Are there techniques for genetic manipulation, editing ...
1
vote
3answers
113 views

If everybody DNA is different then how blood can match even with matching blood group?

We know that everybody's DNA pattern is different in the world. Then how can ´we transfer blood from one person to another person and this person can survive ?
3
votes
1answer
1k views

What is the standing genetic variation?

I am reading this review. In the first part, the author introduces Standing Genetic Variation, described as: STANDING GENETIC VARIATION Allelic variation that is currently segregating within a ...
1
vote
3answers
111 views

Are there tools for automatically parsing glycan names into tree structures?

My colleague and I are working on a project involving data produced at a glycan microarray facility. The array data that came back to us were a list of glycan names (in IUPAC condensed format). We ...
3
votes
1answer
41 views

Functioning of BCG vaccine

I read (from Nature Volume507, S4–S7 (06 March 2014) : For reasons that are poorly understood, BCG protects only infants; it is ineffective in older children and adults. Its efficacy also ...
1
vote
1answer
162 views

What is the blood ejection speed outward from human body vein? [closed]

At what height blood can eject from human vein ? I see, sometime there is direct blood transfer from one person to patient. So sometime blood bottle is kept at certain height and blood is transfered ...
1
vote
0answers
65 views

How do cellphones calculate heart rate?

How do cellphones calculate heart rate ? I understand that the cameras there try to count undulation in blood flow, but is the method of calculation same as that of professional SpO2 monitors ?
2
votes
0answers
56 views

How did the roar evolve from snort?

When Lions roar, or Dogs show aggression, they do that snort-roar thing. They're producing sound while inhaling. How did that come to be when all (?) other forms of sound involve exhaling? Humans do ...
3
votes
0answers
90 views

Data analysis of transcriptome sequencing data [closed]

I want to learn more about the data analysis and statistics on transcriptome sequencing data. I would like to read some important papers of the field and books and maybe some MOOCS, if they are ...
1
vote
1answer
1k views

Difference between inbreeding and interbreeding

Is inbreeding the same as interbreeding? On this site interbreeding is defined as (http://www.thefreedictionary.com/interbreeding): To breed with another kind or species; hybridize. To breed ...
2
votes
1answer
36 views

Evolutionary rationale behind migration proteins

Tumor cells are able to migrate due to specific migration proteins. What is their evolutionary origin? Or are they simply deregulated?
4
votes
2answers
4k views

NaCl role in CTAB - DNA complex in DNA extraction

I have a question about the role of NaCl in the DNA extraction process. So for NaCl concentrations under 0.5M, CTAB and DNA molecules can create complexes. In those concentrations, proteins and other ...
2
votes
3answers
135 views

How quickly is antibiotic resistance lost?

I would imagine the bacterial genome is highly conserved and limited in its space, but maybe I am wrong. If you were to take a strain of antibiotic resistant bacteria and kept them isolated, but fed ...
0
votes
1answer
353 views

What is the difference between fibrogenesis and fibrosis?

Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. I used the word "fibrogenesis" as the outcome of acute inflammation (healing). ...
3
votes
0answers
149 views

Gibson assembly using NeBuilder

I am supposed to construct a plasmid that contains features from two other plasmids. My strategy is to generate three fragments form the two other plasmids. I was encouraged to try Gibson assembly, ...
2
votes
2answers
53 views

Functioning of BRCA2

I know that BRCA2 interacts with RAD51 to repair DNA damage. But how exactly does it function ? What are the other proteins that interact with it ?
7
votes
2answers
362 views

Can a carnivorous animal consume plants with no adverse effects?

While I know that in nature, carnivorous animals are poorly suited to eat plants (largely due to having sharp teeth, not grinding teeth, as far as I know), I was wondering if, in an emergency ...
0
votes
1answer
21 views

Can pulmonary infarction be asymptomatic?

I think it can because there are many parts in lungs. Like for some COPD patients. However, I am not sure if COPD patients can have infarction. Lungs have parallel circulation. Red infarct is ...
1
vote
1answer
155 views

The distance the electromagnetic field of the heart can be detected

A very smart friend of mine seems to get taken in by junk science. He started telling me last night that the electromagnetic field of the heart can be detected beyond 30 feet. What is the actual ...
2
votes
2answers
220 views

pI and pH relationship in context of ion exchange protein purification

I am confused about relationship between isoelectric point and pH in context of ion exchange protein purification. Why we cannot use this method for protein with pI below 7? Thank you very much for ...
0
votes
1answer
26 views

Association of shorter telomeres with heart disease

From this paper Those with shorter telomeres in blood DNA had poorer survival, attributable in part to a 3.18-fold higher mortality rate from heart disease (95% CI 1(.)36-7.45, p=0.0079), and ...
4
votes
1answer
225 views

Sexual Differentiation in Monoecious plants with unisexual flowers

In monoecious plants having unisexual flowers (eg Zea Mays, Ricinus Communis etc), there must be some mechanism as to produce two sexually distinct flowers from the same genotype. Since both the type ...
2
votes
1answer
114 views

What is this plant?

I really like this plant--I'm just wondering what its name is (perhaps genus+species). I think this plant grows in the tropical rainforest in Malaysia. Any suggestions? Thanks!
0
votes
1answer
24 views

Why violets die in closed space?

I'm going to engage into making florariums (a garden in the bottle). I've heard, that violets die in closed space. Do anyone have an idea, what is the reason for that? Lack of oxygen or CO2 or ...
2
votes
2answers
119 views

Can a fungus become resistant to a chemical such as Potassium Permanganate?

A friend used potassium permanganate solution to treat tinea on the hands/feet but after some initial success, the tinea seems to be making a comeback. Could the fungus develop resistance to potassium ...
3
votes
1answer
60 views

How can I re-format my DNA motifs' position weight matrices?

I am working with a set of DNA motifs that are predicted as potential regulatory motifs (e.g. transcription factor binding sites). The motifs belong to several species, and I wanted to cluster these ...
2
votes
3answers
85 views

Real-time PCR result interpretation

I performed real-time PCR and I was looking for expression fold changes for 2 genes and I had two sample pools, one treated and the other not treated (for each gene). The problem is that my ...
0
votes
1answer
166 views

Pathogenesis of Chronic Venous Congestion in Lungs?

I am thinking how CVC in lungs lead to the left-sided heart failure.
2
votes
1answer
160 views

What insect is this..?

Can anyone tell me what kind of insect (if it is one) is this...!! Or is it the pupa of some insect? Well I don't think that the whole big thing is the insect itself, it appears to be just a kind of ...
1
vote
1answer
88 views

What is the pathogenuc mechanism of brown pigment lipofuscin in muscle atrophy?

I think it is autophagy. Lysosomal degradation. Autophagocytosis. Example of the brown pigment (lipofuscin) here: I am not sure if autophagy is the right answer to the "pathogenic" mechanism of ...
0
votes
1answer
51 views

Pathogenesis of chronic venous congestion in skin?

I think CVC cannot lead to heart failure primarily. So let's think its pathogenesis in skin now only. I think the pathogenesis is like this dilation of veins and capillaries due to impaired venous ...
3
votes
4answers
77 views

Can systemic intravascular thrombosis cause brain infarction?

I wonder if the thrombus can pass through the brain-blood barrier because I think small molecules like O2, CO2 and ethanol can pass it. Probably, in some diseases where the permeability of the barrier ...
-1
votes
1answer
86 views

Dimensional analysis Question

So I'm new to the dimensional analysis world and I'm little confused and the answers I'm getting are not convincing :( if the concentration of hemoglobin in a 5ml sample of blood is 34 g/dL. and red ...
0
votes
1answer
100 views

How does DNA mess up

When there is an error in copying DNA (a mutation), what exactly goes wrong? If G goes with C and A goes with T, I don't see how that part can mess up. Is the idea that when the double helix is ...
3
votes
1answer
79 views

Hela live cell confocal laser scanning - reccommendations for good fluorophore that will show good movement

I've been doing a lot of live cell imaging lately mostly using hela cells expressing some EYFP based chimeric proteins. I'm building a video library for an art student here at the university who is ...
2
votes
2answers
326 views

How much of your stock solution should you take to make the 1000 cells/mL mixture? [closed]

You need a solution containing 1000 buccal cells/mL. You count that you have 125 buccal cells in 50uL, from a total solution of 8 mL. How much of your stock solution should you take to make the 1000 ...
1
vote
1answer
31 views

Which inflammatory response with Cytomegalovirus infection?

I am thinking about inflammation process with Cytomegalovirus infection. I first thought it is about chronic inflammation, but then changed my mind because of virus infection. I think cytokines must ...
2
votes
1answer
34 views

Neuroscience: zapping an axon connected to thermoreceptor

Let’s say an experimenter has an electrode that can give a shock to a single axon. She takes that electrode and zaps an axon connected to thermoreceptors in the hand of her subject. I) What would the ...

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