7
votes
1answer
402 views

Do drugs always degrade after they have passed their expiration date?

I have been wondering for some time whether several drugs really have an expiration date. Let's narrow the scope and think about only "common" drugs, e.g NSAIDs, antibiotics etc. For example, would ...
7
votes
1answer
351 views

Do egg laying animals experience a pregnancy?

Does a female animal that lays eggs experience a pregnancy-like period of time, where she will feel and behave differently as if she were fertilized and her body is prepared to lay a fertile egg, not ...
6
votes
1answer
148 views

How is hibernation/aestivation different from anesthesia?

How do hibernation/aestivation happen? I read on wikipedia that a squirrel injected with the body fluids of a hibernating fellow is more prone to hibernation. If hibernation/aestivation are driven ...
5
votes
1answer
61 views

Does a plant have to be alive for its roots to prevent erosion?

One argument often given in favour of saving current and planting additional plants/saplings is the roots hold soil together and prevent soil erosion. Unlike plants that may be uprooted, a large ...
4
votes
2answers
688 views

What is the effect of a pure-oxygen environment on a plant?

Just read What's the effect of oxygen deficit on plants? ; and wondered whether the opposite would have any effect on a plant. That is to say, if a potted plant were placed under a bell-jar and ...
3
votes
2answers
126 views

What is the biological basis for a human's ability to think clearly and be aware while “fighting/competing”?

I'm interested in learning more about the biological systems or hormones or parts of the brain that affect short term (<15 minutes) ability to concentrate attention on the task and be aware of the ...
3
votes
0answers
87 views

What controls the feeling of discomfort/comfort before and after sleep?

I'm interested in which biological systems or hormones are involved in the following phenomenon: Before sleep it may be difficult to find a comfortable position, and muscular aches and pains are more ...
6
votes
1answer
58 views

On the effect of polluted air on health. Is it more gradual, or more immediate?

I've heard time and again that living in São Paulo (a large city in Brasil) takes 1.5 years from your life expectancy. The allegation is that this happens because of air pollution. I am just ...
4
votes
1answer
59 views

Drosophila reference genome

Does anyone know the details about which line they are using to sequence as the Drosophila melanogaster reference genome?
9
votes
1answer
161 views

Black bumps on the cut surface of an avocado

I cut an underripe avocado in half and put half of it, without the pit but with the peel, in the refrigerator. A day later, I see very small black bumps along the cut surface. What are they? What ...
6
votes
1answer
112 views

Macromolecule levels in daughter cells after fission

When a prokaryote undergoes binary fission, how are the non-DNA macromolecules distributed between the two daughter cells? This is motivated by comments on a previous question and a G+ discussion. I ...
4
votes
1answer
101 views

Is there a correlation between incidence of type 1 diabetes and vitiligo?

Does the data indicate that if you have one, the probability of you having the other is higher than that of someone who doesn't have the one?
9
votes
1answer
350 views

Why does this illusion work?

This is another image I found on Google+ All lines are absolutely straight, parallel and perpendicular but why does it appear to have a curvature? Related: How does this illusion work?
3
votes
0answers
62 views

Are mature trees as susceptible to mutation from exposure to radiation as seedlings?

If a plant, say a ficus or a teak, as a sapling were exposed to radiation, and a tree of the same species were present at the same distance, which of the two would be more likely to mutate?
6
votes
1answer
81 views

DNA modifications other than 5-mC/5-hmC/5-fC/5-caC in vertebrate genomes?

Other than 5-Methylcytosine and the more recently discovered 5-Hydroxymethyl, 5-formil and 5-carboxylcytosine DNA modifications found in DNA sequences, what are other DNA modifications present in ...
1
vote
1answer
314 views

Is sperm contagious?

A person may have a cold or any other disease that is an airborne-infection. Is their sperm also contagious? Should the person take any precautions?
3
votes
1answer
48 views

Is there such thing as “biological cycles” of activity/performance/etc in mammals?

I'm looking for some information about the cycles of increased/decreased activity, mental performance or endurance that are related to a mammal's age and the time of a season. First of all, I'm not ...
7
votes
2answers
263 views

How to compute properties of peptides ?

I have been tasked with writing a program for computing properties of a give set of peptides. These peptides are given as 1-letter amino acid sequences and I need to compute the following : Length ...
5
votes
1answer
157 views

Cell proliferation limit and senescence of embryonic stem cells and fibroblasts

I am trying to understand the importance of proliferation limits and cell senescence. In particular, I would like to compare the proliferation limit of Embryonic Stem cells (ES) and fibroblasts (which ...
6
votes
1answer
257 views

Computational/mathematical models for predicting phenotype from genotype

Karr, Sanghvi, et al. (2012) propose a whole-cell computational model for predicting phenotype from genotype in Mycoplasma genitalium. Their model simulates myriad cell processes such as DNA ...
3
votes
1answer
74 views

Text/resource with information on all skeletal muscles and their motor units

Something analogous to an encyclopedia on baseball players with a list of all thier stats would be ideal. I'm not looking for just generic muscle names, locations and illustrations. Good answers ...
3
votes
1answer
88 views

Would a plant survive if it was watered using hard-water?

Hard water is water with high mineral/salt content. I'm told that a potted plant watered with a salt solution dries out sooner or later. Is this true? If so, would a plant survive if watered using ...
3
votes
2answers
218 views

Short-term Lamarckism in asexual single cell organisms

I was reading through the Karr et al. (2012) whole-cell computational model. One of the things they did was to induce single-gene disruptions in their model. They observed several to be fatal, but: ...
3
votes
2answers
176 views

Does body mass have a bearing on reflex speed?

A reflex is an unconscious action in response to some specific stimulus, e.g., blinking an eye, or pulling the hand away from a hot pin I know from school biology, and reading online that withdrawal ...
2
votes
1answer
2k views

What negative effects can pinhole glasses have on the body?

While shopping in the local supermarket yesterday, I was surprised to find this display on one of the shelves. I also realize that I should have taken a pamphlet with me, as well as a picture of ...
2
votes
1answer
425 views

Circulation through the liver in light of drug metabolism

I have a lingering question which stems from an answer that I gave to What hydrolyses aspirin within the digestive tract and blood stream? When a drug or any other substance is absorbed into the ...
6
votes
1answer
215 views

What are the white dots on the tree in this photo?

Today in Kongens Have, I noticed a lot of white dots on bark of trees. There are plenty of them, and they were usually on 'bottom' side of branches. Does anyone know what this could be? I took a ...
9
votes
2answers
127 views

What role does a protein's size have on protein-protein interactions?

Protein-protein interactions are when two or more proteins bind together, possibly for some important biological function. Recently, I'm starting to look more into proteins, and in particular, ...
8
votes
1answer
424 views

A timeline of the odds for survival for fertilized eggs and fetuses

I'm looking for data to build a timeline of the odds for survival of a fertilized egg, i.e., What are the odds it'll last a week? What are the odds it'll last a month? 2 months? (and so on ...
11
votes
1answer
753 views

How does evolution produce complex organs

I've been wondering lately how evolution manages to produce complex organs. It is pretty obvious to me how evolution would select some minor traits like size, resistnce to illness or climate. There is ...
8
votes
3answers
957 views

If body temperature is 37°C (98.6°F), why are most people more comfortable at around 21°C (70°F)?

It may be different for other people, but for me, anything above 32°C (90°F) is very uncomfortable, and my body is inclined to seek cooler temperatures. But I would think that at 32°C, the body would ...
1
vote
0answers
176 views

How do optical illusions work? [closed]

Hello fellow investigators I have two questions about optical illusions 1) A photo mosaic is something like this http://i.stack.imgur.com/Pzplp.png What are the optical principles behind our eye ...
6
votes
1answer
346 views

How and when did a dedicated immune system evolve?

I have recently been doing a lot of research into the interplay between the innate and adaptive immune systems in humans, and mammalian laboratory models. This has led to my reading some interesting ...
2
votes
0answers
62 views

Are there any situations in which phenylephrine is preferred to pseudoephedrine?

In the mid 2000s in the US, due to issues of drug enforcement, pseudoephedrine containing medications were brought behind the pharmacy counter and in most cases require ID, and phenylephrine was ...
6
votes
1answer
120 views

Genetic Diversity and Adaptation

I am somewhat new to evolutionary biology, having studied it on my free time as a computer science student. There is one particular thing that has always bothered me for which I have not seen a good ...
10
votes
2answers
172 views

How did the nucleobases in the Murchison meteorite form?

The Murchison meteorite is an important piece of evidence for abiogenesis, because it contained nucleobases from extraterrestrial origin, as this Wikipedia article explains. These results ...
5
votes
2answers
504 views

Why insects are so energy-efficient while flying?

Why are insects so energy-efficient while flying? Is it because of their light weight and aerodynamics or due to very efficient biochemical transformations (food->energy)?
2
votes
2answers
149 views

Do the simplest bacteria have ribosomes and helicase?

I find it interesting that all life on earth use DNA. I've seen video on how helicase and ribosomes work together to copy DNA sequences (to RNA) with helicase then recreate them using ribosomes. Does ...
8
votes
3answers
9k views

Why can't the brain and red blood cells use fuels other than glucose?

The question is rather straight forward: I have always been curious as to why, but cannot find an explanation online. I can imagine that the mechanism is different for each, but why does brain tissue ...
15
votes
2answers
3k views

Why is glucose our primary source of energy?

Is there any evolutionary reason for glucose being the "main" molecule used as a source of energy, beginning with glycolysis and subsequently cellular respiration (after being converted to two ...
10
votes
1answer
147 views

Does stress physically age our body?

Going by the assumption that stress eventually triggers a flight/fight response, and the subsequent realization that flight/fight puts the body in a system of readiness to use it's available resources ...
3
votes
7answers
380 views

Introductory books about evolution

This days I read some debates on evolution. That made me more interested to read something reliable on topic - I mean books. I'm christian - although I think it doesn't matter on that topic - and I ...
7
votes
1answer
58 views

Sequence of ribosomal RNA

Is it possible to sequence rRNA directly, that is, using the ribosome rather than the DNA from the nucleus? For example, this paper, Complete nucleotide sequence of a 16s rRNA gene from E. coli, ...
4
votes
0answers
164 views

How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?

I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II). Is there any difference in the degree to which these ...
5
votes
2answers
170 views

Why is the human body able to repair a broken bone and not a heart muscle?

The human body can repair skin/organ laceration, fractures, even repair nerves - albeit the duration and rate of recovery differ. For instance: The burn scar on my arm from the hot soldering iron ...
1
vote
0answers
22 views

Are open grounds in the vicinity of new construction more prone to waterlogging? [closed]

In my experience as open grounds are paved over by new concrete work other grounds yet open are proportionately more water-logged after heavy rain. Over time trees in such water logged grounds too die ...
7
votes
1answer
107 views

How does Yeast-two-hybrid detect interactions between several proteins in one experiment?

I am trying to understand the Y2H screening method. I can understand how we can check if two specific proteins interact with each other. For example, if we want to check whether protein A and protein ...
4
votes
2answers
187 views

What is the proper quick freezing /snap freezing protocol for pancreatic tissue?

I would like to do a quick freeze on pancreas from mice. I want to then make sections (30 µm thick). The idea is to preserve a fluorescent staining done in vivo. I do not know if I should place my ...
3
votes
1answer
81 views

Predictable microchimerism

I read in New Scientist recently that microchimerism occurs between previously born siblings and grandparents, not just the mother. Do we know which parts of the genome are likely to be transferred? ...
3
votes
2answers
172 views

How do I create a probe for in situ hybridization?

I tried to make the probe several times but it failed again and again. It usually turns out that the probe after hydrolysis is very very short (maybe around 50nt). I did not check the RNA before ...

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