0
votes
0answers
12 views

book on genealogy, haplogroups, migrations, etc

Looking for a popular science book on the topic. I need a wide-angle expose, not fiddling with minor details. It should also be somehow intertwined with migration. I've recently learned, for example, ...
0
votes
1answer
19 views

Pathogenesis of Chronic Venous Congestion in Lungs?

I am thinking how CVC in lungs lead to the left-sided heart failure.
0
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0answers
11 views

What is the patogenetic mechanism of brown pigment lipofuscin in muscle atrophy?

I think it is autophagy. Lysosomal degradation. Autophagocytosis. Example of the brown pigment (lipofuscin) here: I am not sure if autophagy is the right answer to the "patogenetic" mechanism of ...
0
votes
1answer
27 views

Pathogenesis of chronic venous congestion in skin?

I think CVC cannot lead to heart failure primarily. So let's think its pathogenesis in skin now only. I think the pathogenesis is like this dilation of veins and capillaries due to impaired venous ...
0
votes
0answers
5 views

Can systemic intravascular thrombosis cause brain infarction?

I wonder if the thrombus can pass through the brain-blood barrier because I think small molecules like O2, CO2 and ethanol can pass it. Probably, in some diseases where the permeability of the barrier ...
0
votes
0answers
7 views

Is this dystrophic calcinosis in anthracis?

Coalworker's pneumoconiosis with multifoci: There are macrophages filled with dust (exogenous accumulations). I am thinking if there is happening a cellular adaptation (dystrophic calcinosis) to ...
0
votes
0answers
19 views

spinal cord lesion and result in somatic sensation

Jimbo suffers a lesion to the entire right half of the spinal cord at the T6 level. A few weeks after his injury, his doctor tests his right and left legs for somatic sensation and tone. fill out her ...
0
votes
0answers
8 views

To visualise the embryonic development of skeleton and muscles?

I am trying to find a visualisation for this topic, preferably a video. Some facts which I would like to have in the video(s)/visualisation Ossification starts usually with 3 primary centers: 1 ...
0
votes
0answers
7 views

To characterise diameter of capillaries in organs

I know that there exist Continuous capillaries (skeletal muscle, adipose tissue, connective tissue, pulmonary circulation), Fenestrated capillaries (small intestine, renal glomerulus, exocrine ...
0
votes
0answers
11 views

What is the quality rate of intrinsic autoregulation in the heart?

Autoregulation is the maintenance of constant blood flow to an organ in spite of fluctuations in Blood pressure. It involves the relaxation of myocardium and contraction. It is local. I know that ...
0
votes
0answers
30 views

Lethality of a stab wound to the back

How deadly is a stab in the back? Video games, movies, and other fiction would have us believe that a backstab against a foe with a modestly-sized blade leads to immediate and certain death, having a ...
0
votes
0answers
17 views

Does Yerba Mate contain Beta carbolines like harman and norharman?

I know that this is true of (roasted) coffee but haven't been able to find any reliable information about mate in its smoked or steamed state. Thank you.
0
votes
0answers
17 views

Are there any forms of heart failure where cell size decreases?

I think hypertrophy happens in most of the cases. However, I am not sure if hypertrophy always happens. I started to think about wet lungs (pulmonary reason for the left-sided heart failure). Can the ...
0
votes
2answers
45 views

Databases for metabolic pathways of human disease

Which databases contain the metabolic pathway of human diseases? I have searched Metacyc and KEGG but didn't find the appropriate metabolic pathway.
0
votes
0answers
34 views

Why do gay people exist? [duplicate]

I mean no disrespect to gay people - this question isn't intended to be judgemental or homophobic at all. I also know nothing about biology so please excuse my ignorance if this question ends up ...
0
votes
0answers
16 views

Southern/Western blot analysis and pedigree diagram? Help needed. [duplicate]

Hello everyone. I urgently need help with this question please. I have filled in the blanks using the results in the figure provided in the sheet. However, for number (b) is a little hard to ...
0
votes
1answer
30 views

What are the physiological roles of Hydrogen sulfide?

I am thinking why hydrogen sulfide has its effects in the body. For instance, it is one Salmonella's virulence factor. I am not sure if such a balance equations holds ...
0
votes
1answer
23 views

What are the purposes of granulocytes in acute inflammation?

I heard the phrase Neutrophilic leucocytes are kings in the acute inflammation. Neutrophils are granulocytes, while leucocytes are not granulocytes. I think this statement refers to the fact ...
0
votes
0answers
34 views

What are the highest and lowest possible pH, paCO2, and HCO3 in the blood of living human?

What are the highest and lowest possible values of pH, paCO2, and HCO3 in the (arterial or venous) blood of a living human being?
0
votes
0answers
44 views

Are DNA molecular motors described by cellular automata rules?

While watching this Molecular Visualizations of DNA it struck me how much the motion resembles Conway's Game of Life. And not only visually; each molecule/atom is described by a finite set of ...
0
votes
0answers
26 views

Capsule and Antiphagocytosis as a pathogenesis factor

I am thinking the pathogenesis factor (capsule) of Pseudomonas aeruginose as an example: antiphagocytosis $\to$ anti antibodies (I think AB is antibodies) and complement; anbiotics ...
0
votes
1answer
35 views

Hypovolemia and orthostatic hypertension

What is the physiological mechanism behind the occurrence of orthostatic hypertension in the presence of hypovolemia?
0
votes
0answers
32 views

Gene linkage/mapping

I need some help with this question in the image posted. As you can see in the instructions, I'm asked to map the genes. So the first thing I did is write out the alleles corresponding to each ...
0
votes
0answers
12 views

What are the movement mechanisms of thrombus?

I am thinking how thrombus (veins, arteries and heart) can move. Secondary mechanisms come to my mind only: some enzyme which lyses it, probably adhesion mechanism. Blood circulation (flow rate) is ...
0
votes
2answers
34 views

Why is succinate dehydrogenase attached to the inner mitochondrial membrane?

Succinate dehydrogenase is attached to the inner mitochondrial membrane.All the other enzymes of the Krebs cycle are located in the matrix of mitochondria. What is the biochemical reason behind ...
0
votes
0answers
20 views

Can we define biological age?

How can we define ageing from a biological standpoint without making an appeal to chronological age? Related, but less important, are there any metrics we can use to determine someone's biological ...
0
votes
0answers
29 views

comparing conventional phylogenetic tree to phylogenetic trees which are based on enzymes

I built trees (for 4 organisms: mouse, human, drosophila and C-elegans) for different enzymes family, compared them to the conventional tree, and try to explain them. how would you explain these ...
0
votes
0answers
34 views

Genome Assembly Using Reads

I'm taking an online bioinformatics class and I am stuck on a problem. The resources I have found don't help that much. Here is the problem: "Assemble the error-free reads from a circular genome on ...
0
votes
0answers
21 views

How to start Diagnostics of Enterobacteriaceae?

I am thinking what is the Diagnostics for Enterobacteriacea and particularly Shigella, Yersinia, Vibrio, Campylobacteriacea, Helicobacter pylori, salmonella and Proteus. I got today advice that start ...
0
votes
0answers
29 views

Best way to automatically link Gene Entrez ID with Gene Symbol in TCGA

I am trying to figure out how to link Gene Entrez ID with Gene Symbol, for TCGA dataset. So far, I have found this ftp directory with Gene info updated daily. But, for Entrez ID 728661, I have found ...
0
votes
0answers
19 views

Macrophage death by toxin. Little balls inside cell? What type of death?

After I treated J774 cells ( a mouse monocyte/macrophage cell line ) with Clostridium difficile Toxin B (1 ng/ml for 44 hours), I noticed several small circles inside of a seemingly dead cell. I'm ...
0
votes
1answer
30 views

Does adding milk to cereal make it harder for our body to absorb the vitamins and minerals from the cereal?

I add about 3/4 cups of Blue Diamond almond milk (unsweetened) every morning to a single serving of Cheerios. The milk contains filtered water, and I read that drinking water with food at the same ...
0
votes
1answer
18 views

Which direction are wild beehives combs oriented?

Is it on the North-South axis, the East-West axis or some other orientation?
0
votes
0answers
54 views

Genetic Linkage/Mapping question Help

Hello everybody! I need some help with this question in the image posted. As you can see in the instructions, I'm asked to map the genes. So the first thing I did is write out the alleles ...
0
votes
0answers
14 views

Testing gene against resistance and susceptible cultivars

I have one gene cloned from plant fungal pathogen using pure culture. Now I want to characterized this gene using molecular methods for which I have few resistance and susceptible cultivars of the ...
0
votes
1answer
34 views

Effect of respiration on Arterial pressure

I am trying to explain the effect of respiration on arterial pressure. I am looking preferably some visual way to show it. How can you show the effect of respiration on arterial pressure? I am ...
0
votes
0answers
13 views

What is a good ECG book on Schema level?

I need to know ECG on scheme level, not on Guyton level. The problem is that I have read it on Guyton level and now I should find some review book about this review level. For instance, the ...
0
votes
0answers
36 views

Prepare Mueller-Hinton agar at home

I'm doing a self science project, it's easy if i have a lot of money to buy a Mueller-Hinton agar bottle from Ebay for about 110$ (include shipping cost). The main problem is it is very expensive for ...
0
votes
1answer
14 views

Has H.pylori paracellular activity?

I know that it has transcellular activity i.e. it can pass through neighbouring cells. However, I am not completely sure if it does not have paracellular activity, see this: H. pylori did not ...
0
votes
0answers
16 views

How do you express and detect GLP-1 receptors?

I am currently working with a peptide which is an analogue for glp-1, but during invitro studies am not able to detect for the presence of GLP1- receptors. The cell line used is Min-6. How do I detect ...
0
votes
1answer
25 views

how many chemcial species on average in a typical plant and animal cell

I want to know what sort of range there is on the number of different chemical species in a typical plant and animal cell. Failing that, some specific examples (with sources please) Thanks
0
votes
0answers
18 views

How many centrioles/basal bodies are there in multi-ciliated organisms throughout the cell cycle?

I thought there were only two centrioles per cell, that convert to the basal body at some point during the cell cycle. I also thought there's one basal body per cilium, so I'm not clear on where the ...
0
votes
0answers
32 views

Replication of DNA in E. coli: what are DARS and RIDA?

I understand what is DnaA, its role in replication and the fact that it's only active when binding ATP. I don't understand what are DARS and RIDA and how they control the amount of DnaA-ATP:DnaA-ADP
0
votes
0answers
26 views

Sleep: a tale of two morning stimulants

According to "common knowledge", morning/afternoon exercise is "good" for sleep (in the long run) and caffeine is bad (less so in the morning). However, both of these stimulate the brain; exercise ...
0
votes
0answers
16 views

Does biotin affect downstream experiments, such as RT-qPCR?

I have two biotins--one of which is binding my RNA with cleavable bonds, and the other with irreversible bonds. Does biotin have an effect if it keeps its bonds with RNA? If it does, why is this the ...
0
votes
0answers
20 views

The biological basis of inflamatory foods: the list of attributes and the concrete example of milk vs kefir

I wonder if anyone has some interesting matterial on the biological basis of inflamatory foods. I'm interested in pin-pointing the (in)complete set of (known) causes in the form of a list and maybe ...
0
votes
1answer
213 views

Which processes are during the latent period of ventricular contraction?

The latent period is the time between the start of depolarisation and the start of contraction. I know that the contraction of ventricles starts after sufficient influx of Ca2+ and threshold ...
0
votes
0answers
19 views

To define the total Resistance of Systemic Blood Circulation

Some systems are in parallel so let's just call those like $R_{\text{lungs}}$. I got this formula $$R_{\text{total}}=R_A+R_a+R_c+R_V+R_v$$ where $R_c$ capillaries, $R_a$ arterioles, $R_A$ Small ...
0
votes
0answers
18 views

Why is the resting membrane potential of cardiomyocyte more stable than that of Pacemaker in Phase 4?

There must be some channels that keeps this very stable. It seems to be that the resting membrane potential of pacemaker cells is steadily increasing until the threshold voltage. I think the same must ...
0
votes
0answers
11 views

Why is Aorta sometimes called Compression chamber?

I find this statement that Aorta is called Compression Chamber in my study materials. Aorta can it keeps blood flowing it can accumulate potential energy for bumping and compression However, why ...

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