2
votes
1answer
69 views

Carrying or packaging capacity of SAD B19 dG rabies virus

I'm wondering about the carrying capacity also referred to packaging capacity or loading capacity (how many base pairs can be packed efficiently into virions) of the pseudotyped rabies virus SAD-dG as ...
2
votes
2answers
147 views

How does your body know when it is infected so it can invoke a fever?

How does your body know when it is infected with a virus or bacteria so it can invoke a fever or ramp up the immune system?
2
votes
1answer
762 views

Problems with analysis of small RNAseq data - Adapter trimming

I have always faced a problem while analyzing small RNAseq data, at the step of adapter trimming. Overview of small RNAseq (Illumina) RNA is size fractionated using columns or PAGE 3' and 5' ...
2
votes
1answer
389 views

Strange behavior of a DNA gel

I ran a PCR product of ~300 bp on a 2% TAE-agarose gel for 30 minutes. I used Sybr-safe as a DNA stain. Voltage was 80V. When I imaged the gel, the DNA on the bottom half of the gel, including the ...
2
votes
1answer
135 views

EGFR, sialylation, and cancer progression

EGFR (epidermal growth factor receptor) has been intensively studied in cancer and treatments have been developed to inhibit EGFR signaling. Sialylation of EGFR is known to block dimerization and ...
2
votes
1answer
135 views

What's the difference between a free chromosome fragment and an extrachromosomal array?

This is reference to a review on C. elegans mosaic analysis by Yochem and Herman, in which the authors make a distinction between free chromosome fragments and extrachromosomal arrays. For the ...
2
votes
1answer
66 views

Are (baseline) high blood levels of melatonin associated with either circadian rhythm or mood disorders?

(Exogenous) melatonin is administered at night for treatment of circadian rhythm disorders, but melatonin taken during the day is linked with depression. I would like to know if high blood levels of ...
2
votes
1answer
102 views

Is Hypericum Perforatum (St. John's wort) a C3 or C4 plant?

I've been curious as to which photosynthetic cycle St. John's wort uses to synthesise glucose and more complex carbohydrates. I know it probably won't be the crassulacean acid metabolism (CAM) cycle ...
2
votes
1answer
53 views

Confusion related to the DAVID tool

I am trying to use the DAVID tool to do some gene analysis. I have some probe set intensities for some cancer cell lines. I found this link in the DAVID tool http://david.abcc.ncifcrf.gov/tools.jsp. I ...
2
votes
1answer
246 views

Is there an “Adam and Eve” for each new trait during (not just human) evolution? [duplicate]

Do new beneficial mutation evolve simultaneously and independently with several individuals of the same specie or only with one specimen who then transfers it to all of the specie? In other words, ...
2
votes
1answer
137 views

Why do cells have an average 'life span'

I've heard of Henrietta Lacks. As a result of a genetic mutation, her cells never died. I've heard/read that overtime, our cells stop multiplying as much, (as an effect of aging). Why? Why do we age? ...
2
votes
1answer
84 views

Colloids in digestion

I am looking for examples of colloids involved in digestion for a cross-curricular (bio-chem-physics) lesson plan. Although I have found references implicating colloids in both lipid and protein ...
2
votes
1answer
186 views

Why do marine animals have fins?

Why do Marine animals have fins.
2
votes
1answer
48 views

What's the simplest set-up to demonstrate soiless plant growth to middle school students?

I'm looking for a simple, inexpensive way to demonstrate that soil is not needed for plant growth to middle school students. I plan to germinate bean seeds in cotton, but where do I take it from ...
2
votes
1answer
209 views

Is Webmedcentral a reputable scientific publisher?

I am a student, and I have written a paper (in drug discovery) which I want to publish. While searching for possible journals I came across Webmedcentral. Is Webmedcentral a reputable scientific ...
2
votes
1answer
69 views

Do siblings have a bias toward believing they look different from each other?

Anecdotally, I have observed (myself included) that siblings tend to think that they look less similar to each other than an unrelated observer would say. Is there any experimental data to back this ...
2
votes
2answers
814 views

Is it possible that the recipient of a heart transplant would display some of the donor's personality traits, as if the heart has memories?

I've read somewhere that after a person has a heart transplant, it is possible that his/her attitude, action or behavior would change slightly or significantly, as though he/she possesses some aspects ...
2
votes
2answers
117 views

Can a new Y-chromosome be created?

The major gene of the Y-chromosome is SRY. Would it be possible to get the X-chromosome and add SRY to create a "fuller" Y-chromosome? What advantage does the skinny Y-chromosome give an individual ...
2
votes
1answer
72 views

Are humans hardwired to continue gathering resources after the costs outweigh the benefits?

An animal will stop foraging in a berry bush if the perceived cost of searching for berries remaining is greater than the cost of finding another bush which isn't as picked over. People do the same ...
2
votes
1answer
201 views

Can Taq polymerase be used instead of polymerase Vent exo (-)?

Instead of using polymerase Vent exo (-), can I go with the usual Taq polymerase? Do the PCR conditions change (the temperature and master mix concentrations ) in the these two conditions? Do the ...
2
votes
1answer
57 views

Is it ok for Chili pepper plant's fruits to fall into its soil?

I wonder if Chili pepper's fruits which fall into the soil near the plant will harm it, since the peppers are so spicy for people.
2
votes
1answer
293 views

Insulin and monoclonal antibody production

When producing insulin, the gene for its production is inserted into the plasmid of a bacterium that is allowed to replicate freely. Why can't the same thing be done with antibodies (as I understand ...
2
votes
1answer
61 views

Is it more likely to develop a throat-ache at night?

I have noticed that I rarely develop phlemmy throat-aches in the daytime, but often notice them after I have been sleeping. Is this a recognised phenomenon? Could it be because viruses or bacteria ...
2
votes
1answer
115 views

How can I compare rates of evolution for two sets of proteins?

I have a list of candidate proteins as the result of my analysis. I am now trying to find various characteristics that they have in common. One of the things I would like to check is if my candidates ...
2
votes
1answer
143 views

By What Mechanism can Felines Reverse Diabetes?

To my knowledge house cats (and likely other felines) are the only animal able to go into remission after onset of Type 2 diabetes mellitus. I don't have a reference, this has been by peers in my ...
2
votes
1answer
32 views

What range of dose should be used?

This is a dose-response experiment testing a new cancer drug. the darker line represents cancer cells. what range of dose should be used? I think it's 2-4 because this affects cancer cells only. is ...
2
votes
1answer
206 views

What marine animals exhibit deep hibernation/aestivation?

Do marine animals exhibit deep hibernation/aestivation as land-based creatures do? If not, Why?
2
votes
1answer
87 views

Why glycoproteins are better than non-glycoproteins in fulfilling biological tasks?

I have just an intuition that the carbohydrate part of glycoproteins help them to fulfil those tasks like in plasma membranes. You can also get many more receptors if you can use carbohydrates too. ...
2
votes
1answer
81 views

What does self-preservation stem from? [closed]

Self-preservation, or preservation anyway, probably happens throughout the animal kingdom, and perhaps through the plant kingdom as well (some plants/trees, apparently, produce chemicals to repel ...
2
votes
1answer
86 views

Reattaching body parts

Is there any living organism that has the ability to remove and reattach body parts at will? I'm not talking about regeneration (like in starfish). Say I'm chasing prey, and I decide that my tail ...
2
votes
1answer
458 views

Has the age at which menopause occurs changed throughout history?

I was reading recently that the age of menarche has decreased in the last 150 years, and was wondering if the age of menopause in humans has also changed recently? Would there be selective pressure ...
2
votes
1answer
916 views

Is it possible to still grow taller after grow plates have been closed?

In addition, when do we know we stop growing taller? Or we keep growing taller? To the first question: Recently, I went to a doctor to have a check up, he said that my growth plates are closed and ...
2
votes
1answer
362 views

Can visual acuity be improved?

Is it possible to completely cure myopia using natural methods (i.e. not with Lasik etc.)?. I have seen websites claiming that exercising the eyes will help improve eyesight. Is this true?
2
votes
1answer
152 views

Can epigenetic changes affect reproductive success?

This is prompted by niallhaslam's answer to this question [Since Darwinian times, has there been any striking/notable effects of evolution on humans?]. A comment by Alan Boyd asks whether epigenetic ...
2
votes
1answer
55 views

Biology view on trait variability

In reading the annotated Origin... I have come to the following note by Costa on p. 168: Again, modern biologists would disagree with Darwin's idea that especially well-developed traits vary to a ...
2
votes
1answer
48 views

What is the title of Darwin's paper on cellular structure?

I read somewhere that Darwin wrote a paper that dealt with cellular structure, but I've been unable to find the title or contents of the paper because Darwin wrote such a volume of material. What is ...
2
votes
1answer
322 views

How does the brain instinctively know the math behind Newtonian Physics?

A 10 year old child does not have the intellectual power to accurately calculate the energy required to throw a ball an arbitrary distance. Yet they are able to accurately throw a ball at a ...
2
votes
1answer
77 views

Are there any organisms with larva more advanced than adult form?

Usually adult organisms are more sophisticated than corresponding larva, i. e. frogs, mosquitoes, fish. Are there species where the opposite is true?
2
votes
1answer
251 views

Are Bovine serum albumin, Avidin, Ficoll-70 and Dextran-70 positively charged or negatively charged? [closed]

Bovine serum albumin, Avidin, Ficoll-70 and Dextran-70,are they positively charged or negatively charged ? And which other solvents can be used as a substitute to water for preparing solutions in each ...
2
votes
1answer
257 views

What happens to colloidal particles in a liquid medium? And how to stabilize it?

Definition Colloid is a dispresion of small particles of one material in another. Definition 2 (Wikipedia) A colloidal system consists of two separate phases: a ...
2
votes
1answer
185 views

Why do the sick and unhealthy trees leaf out first in spring?

It's spring. The time of year that trees start to leaf out. I have been watching them, and noticed an interesting pattern. The unhealthy trees of a species leafs out first. I've noticed this ...
2
votes
1answer
98 views

Structure of RAP Antibodies (Specifically RAP-5)

[EDIT] - Have just found not one but two papers that address my structure problem. However they concern RAP-1A, so I guess my question is now what is the difference in structure and function of ...
2
votes
1answer
132 views

What are the effects of combining rapamycin with dietary restriction?

Are the effects additive or subadditive? In many ways, rapamycin acts like a CR mimetic, but even CR can only go so far.
2
votes
2answers
35 views

Conversion of glucose to glycogen

Why is excess glucose, as a glycogen, stored in only a limited amount as compared to the lipid in our body? Why is mature glycogen arranged (polymerized) in 12 tiers polymer?
2
votes
1answer
20 views

Identification of unknown bagworm (Singapore)

This bagworm was found in Singapore (near McRitchie Reservoir) some time in June 2012. This is the plant from which the bagworms were obtained: A few examples of the bagworms: The bagworm when ...
2
votes
1answer
21 views

In a typical population, what might the percentage of plants be to predators and everything inbetween?

I'm not sure if this will be a simple question that is almost a natural law for an ecologist, or a complex serious of assumptions. I vaguely remember from school that only 10% of the energy is ...
2
votes
1answer
19 views

Plant dependence on CO₂ levels

I was wondering which kind of plants would survive longest without CO2 : plants with fatty, thick leaves or plants with thinner, less fatty leaves? And can we conclude that the plant species that are ...
2
votes
1answer
53 views

Why can't we call dog breeds different species?

I understand this question might fall into opinion based, but I'm trying to write it so that it meets the "Many good questions generate some degree of opinion based on expert experience" part and not ...
2
votes
1answer
30 views

Is there any disadvantage to having a really low adipocyte count in our times?

The key feature of adipocytes seems to be energy storage. Today humans in Western countries don't have to hunger and have therefore less need to store energy in fat cells. Do adipocytes have ...
2
votes
1answer
33 views

Whole genome sequence analysis software

Please help to choose Bioconductor R packages and other software for the whole genome sequence data analysis and, in particlular, the goals of false discovery mutation rate, mutations exclusion, ...

15 30 50 per page