9
votes
5answers
2k views

Is it possible to genetically modify a plant at home?

Would I be able to genetically modify a plant at home? What equipment will be necessary? I think it might be a fun change from the 'norm' of regular hybridisation, to try some inter-family gene ...
9
votes
1answer
789 views

Did the eugenics program in Nazi Germany have a measurable effect? [closed]

Did the killing or sterilisation of people considered as living a "life unworthy of life" in Nazi Germany have any measurable effect on the "average health" of Germany? Is there any statistical ...
9
votes
2answers
368 views

How is human biological clock modelled in modern science?

Im an engineer by education and i program a lot, so the question sounds weird to people from other disciplines. Im trying to better understand the human biological clock. Yet i do not really know ...
8
votes
3answers
215 views

Splice in with CRISPR/Cas

I need to splice a gene into a human cell genome, with highest rate possible. I mean, doesn't really matter where the gene enters, nor does it matter if some cells die as a result of this. CRISPR ...
8
votes
1answer
198 views

Genetic Drift: Models, assumptions and empirical observations

There two main mathematical models to describe the process of genetic drift are Moran model and Wright-Fisher model. My questions concern the assumptions of these models, the existence of other ...
8
votes
3answers
5k views

Why doesn't recombination occur in male Drosophila?

"Males do not show meiotic recombination, facilitating genetic studies." For a while I have known that this phenomenon occurs, this quote comes from the Wikipedia page on Drosophila melanogaster, ...
8
votes
4answers
483 views

Why people like to see pornographic scenes, but do not feel the same about eating scenes? [closed]

This question may seem funny, but I think biology must have good answers. I think no more explanation is needed. I really thought about this and searched for an answer, but there is nothing yet. If ...
8
votes
1answer
397 views

Has any large-scale origin-of-life simulation/experiment been done?

I have been thinking a little about the origins of life, and was further inspired by this question: How did the first self replicating organism come into existence? I can accept that we don't quite ...
8
votes
1answer
128 views

What happens when we know that there is something that we forgot but we can't remember what it was?

I think it happens for everyone that sometimes we go to a room and forget why we went there. Is there any research or article on this?
8
votes
1answer
341 views

How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?

I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II). Is there any difference in the degree to which these ...
8
votes
1answer
66 views

Downloadable worldwide database of disease statistics?

I am looking for a downloadable database of disease statistics. I have emailed the good folks over at HealthMap, but they haven't gotten back to me yet. As far as I can tell, their data relevant to ...
8
votes
1answer
6k views

Difference between strand-specific and not strand-specific RNA-seq data

I would like to ask the difference between strand-specific and not strand-specific dataset. As far as I know, strand-specific data means that we know which strand the transcript is from. I do not ...
7
votes
2answers
157 views

Why did the Brain develop in the front in most organisms?

I was wondering: why most, well, pretty much all organism with a brain have it right in front of their bodies or at the top.
7
votes
1answer
833 views

Why do human eyes glow red on a photo and dog's eyes green?

Previous Research I know that cameras sometimes come with an anti "red eye" functionality that involves two flashes, presumably the second flash coincides with the shutter opening. Question Why do ...
7
votes
2answers
179 views

Can a single axon propagate multiple simultaneous action potentials?

I have not been able to locate any research that indicates whether a single axon of a neuron or nerve cell can conduct multiple simultaneous (i.e. spatially separate) action potentials. I am aware ...
7
votes
2answers
6k views

What determines if a gene is dominant or recessive?

Going back to my high school days we were taught about dominant and recessive genes. We were taught how to calculate the geneotype and pheneotype of potential offspring using a small table (forgotten ...
7
votes
3answers
529 views

How can you test what color different people perceive?

If I would show someone a yellow object and ask them, "is this object yellow?" That person would say "yes". But I could never know if my perception of the color yellow is the same as that other ...
6
votes
2answers
416 views

Why are humans and almost every species on earth symmetrical?

I admit I'm not very learned on the subject of evolution, I just started researching it for myself about a week ago. One of the things that I don't understand is why humans and almost every other ...
6
votes
1answer
1k views

How do neurons form new connections in brain plasticity?

I've been reading about brain plasticity and how the brain can "rewire" itself. One of the things that is not clear to me - how neurons can establish new connections. Does this rewiring mean that ...
5
votes
3answers
552 views

Books for beginners [closed]

I want to study biology. I have zero previous knowledge of biology but I know Physics, Chemistry and Maths. From which book should I start? I have heard about Campbell Biology, but it is very costly ...
5
votes
1answer
104 views

enzymes that stabilize DNA loops

As a follow-up of a previous question, I would like to know what enzymes or protein complexes have been used to manipulate DNA samples into stabilizing DNA loops. I have read that cohesin is one of ...
5
votes
1answer
216 views

Is there such thing as Animal non-verbal body language?

Have there been any studies done on the animal use of their bodies to signal, communicate or express their emotions, particularly to members of other species (ex: humans)? I've been observing a very ...
4
votes
1answer
232 views

Relationship between nerves and axons

I just wanted to get a realistic viewpoint of our nervous system. I understand arteries and veins, but I wanted to know how similar our nervous system is to that? I understand we have neurons ...
4
votes
3answers
155 views

Why are the fertility rates of large predators kept low?

Predators at the top of a food chain, like lions, seem to have a relatively low fertility rate, which fits well to the ecosystem and avoids overpredation. But what is the mechanism that keeps the ...
4
votes
1answer
752 views

Why does max heart rate decrease with age?

I have heard that max heart rate declines steadily with age, and can be approximated by the equation Max Rate = 220 - Age. What is the physiological reason for this decline, and how is it ...
4
votes
1answer
142 views

How to calculate the effective population size ($N_e$) with overlapping generations?

From this Source: If generations are overlapping, then the effective population size $N_e$ does not equal the population size $N$. I know mathematical formulations in order to find the effective ...
4
votes
2answers
200 views

Gas from bacteria that's not methane

Is gas produced by bacteria always mainly methane? Or, are there bacteria out there that produce some biogas composed mainly of hydrogen, natural gas, propane, butane?
3
votes
2answers
343 views

How are DNA segments selected in PCR?

I understand that in PCR we're able to amplify only selected portions of the DNA... however despite reading it from multiple sources, I cannot figure out how this selection actually takes place. I ...
3
votes
1answer
408 views

Will the increase in atmospheric carbon dioxide lead to larger insects?

From my understanding, the increase in atmospheric carbon dioxide will also increase oxygen levels. That makes me wonder if in the near future insects will grow larger than they are today, since their ...
3
votes
2answers
526 views

Initial population when i count backwards?

My question is dealing with how many ancestors it took to produce me: --> to produce me it took 2 people (my parents) = ($2^1$) people = 2 --> one generation further included = ($2^1 + 2^2$) people ...
3
votes
2answers
2k views

Ill effects of urea and NH₃ on metabolism

What exactly does urea do that harms our body? Does it interfere with our cellular processes or disturbs the colloidal onchotic pressure of our blood? I have heard that NH3 damages the brain. What ...
2
votes
1answer
67 views

Why does the number of mutations per individuals follow a Poisson distribution?

I was reading this review. On page 11, left column, first paragraph, one can read: [..] there is a Poisson distribution of the equilibrium number of mutations per individual, if fitness effects ...
2
votes
1answer
479 views

Can DNA & RNA be considered as nature's programming language?

The final frontier of Biological Sciences could be considered understanding the effects of variation in the DNA (and RNA). If after fertilization the DNA of the zygote could be genetically ...
2
votes
1answer
82 views

Fast standing and the heart's insufficient accommodation of the increased venous return

Assume you are 45 minutes on the supine position. Furthermore: you stand all of a sudden and fast and without sympaticus activity. The venous return (smooth musculature of vessels) accommodates ...
2
votes
1answer
2k views

Ancestral Allele explanation

I'm having some trouble understanding the concept of ancestral allele. What exactly does it mean? What does it have to do with Identity by descent/state? What does it have to do(if anything) with ...
2
votes
1answer
601 views

What can cause the bloating in high protein diet of Whey proteins?

I am thinking what can cause the swelling of gastrointestinal system i.e. bloating after high protein diet of Whey proteins. Liver does breaks those proteins to branched chain amino acids (BCAA), ...
2
votes
1answer
67 views

Effective population size when the population sizes varies from season to season

Let's think of a species which has four generations per year and which population size changes from season to season so that the population size is 100 in summer, 200 in spring, 50 in autumn and 20 in ...
2
votes
2answers
176 views

Radiation and “Safe Dose”

I've read about safe doses of radiation, briefly. Why is there such a thing a safe dose? Can't any radiation give you cancer? Why is it more and more dangerous to take in larger and larger doses? Just ...
2
votes
3answers
127 views

Can antibiotic resistant bacteria compete with normal one in an antibiotic free environment?

The question is based on an intuition that antibiotic resistance can't come along. This mutation will probably make bacteria less tenacious. Is there any research how AR bacteria compete with normal ...
2
votes
1answer
2k views

What would be the best design for spike-and-recovery and linearity-of-dilution validation experiments in one 96-well ELISA plate?

I have searched in the web for a detailed explanation of doing such validation experiment, but unfortunately couldn't find a satisfactory one. I came across the following sources: Thermo ...
1
vote
1answer
70 views

Additive genetic variance with $n$ loci

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
1
vote
1answer
109 views

Additive genetic variance with $n$ alleles

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
1
vote
1answer
29 views

To understand clearly extraintestinal diseases

Extradistestinal disease seems to prefer to "bowel" diseases, I think this is about diseases outside gastrointestinal tract so stomach. Consider diseases ulcerative colitis and Crohn's disease ...
0
votes
2answers
143 views

What is the name of the condition where no pacemaker cells are active in the heart for a short-time?

Assume that the heart is beating, but no pacemaker cells are working for at least 15 seconds. This would be a very long compensatory pause if extrasystole started it. There may be some low frequent ...
33
votes
5answers
7k views

What does the human body use oxygen for besides the final electron acceptor in the electron transport chain?

My biology teachers never explained why animals need to breathe oxygen, just that we organisms die if we don't get oxygen for too long. Maybe one of them happened to mention that its used to make ATP. ...
24
votes
2answers
585 views

Smallest viable reproducing population

What is the smallest viable reproducing population, such as in a human population. By viable I mean a population which keeps genetic defects low (enough). A very strongly related question: what is ...
21
votes
3answers
38k views

Why do mammalian red blood cells lack a nucleus?

How did the red blood cell in humans get to lose its nucleus (and other organelles)? Does the bone marrow just not put the nucleus in, or is it stripped out at some stage in the construction of the ...
20
votes
4answers
3k views

Where does the 'C' in exhaled CO₂ mostly come from?

When a human being exhales CO₂, what is, by the numbers, the main source of carbon atoms exiting the body in this way? I mean what class of cells, or which tissues are the biggest on a pie chart of ...
18
votes
3answers
1k views

How long can I store extracted RNA?

If I extract RNA from a (leaf tissue) sample using a one-step phenol:chloroform extraction, how long can those samples be stored at -80°C? And how many times can I defrost and refreeze them before ...
16
votes
5answers
1k views

Are there any examples of sudden leaps in evolution?

As far as I understand, various abilities like flying, sight, hearing etc. were caused by slow evolution, where those with a greater ability to to these things had better chance of survival. (If this ...

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