2
votes
1answer
877 views

Lyonization and X-linked disorders?

Lyonization or X-chromosome inactivation is the conversion of all but one, X-chromosomes in Females into non-coding heterochromatin (i.e. deactivated) leading to the formation of one or more Barr ...
5
votes
1answer
313 views

Empirical evidence for species selection

Do we have any empirical evidence in favor of species (or lineage) selection? Do we know some cases that can only be explained (or seem to be only explained) by lineage selection? What are today the ...
1
vote
2answers
223 views

Question about production of CFTR protein

How do organelles such as ribosomes, ER, Golgi and vesicles produce CFTR protein and mucus?
4
votes
1answer
94 views

Which of Perutz et al's protein structures other than 3₁₀ helix were correct?

In 1950, Bragg, Kendrew and Perutz published "Polypeptide chain configurations in crystalline proteins" (open access) and were famously 'proved wrong' by Pauling, Corey and Branson the following year, ...
6
votes
4answers
133 views

How to measure bacterial content

I´m using water container placed on a radiator to humidify room air. Someone might argue that it is a perfect nest for bacteria. I have to put copper coins into the water to kill the bacteria. I ...
4
votes
1answer
64 views

How much can you learn about species variation from a skeleton?

I just read about the discovery of the 1.8-million-year-old human skull in Georgia, and how it suggests that early humans were all one species instead of distinct ones. Would an archaeologist ...
3
votes
1answer
219 views

Ventral stream pathway and architecture proposed by Poggio's group

Please can you give me a very brief explanation about all functions in the ventral stream architecture summarized in this figure: This figure is from Serre et al.'s A quantitative theory of ...
1
vote
2answers
31 views

What are examples of genes succesfully reproducing in ways that is in conflict with helping the individual creating offspring

Most of the time, our genes have common interests with our "self". We reproduce well if and only if our genes reproduce well. In some cases, like in bees, the haploid bees can survive better if they ...
4
votes
1answer
3k views

Isotropy of sarcomere bands in skeletal muscle cells

As seen under a polarization microscope, the A-Band in skeletal muscle fibres is so named because it is anisotropic in its refractive index which is a characteristic of orderly crystalline structure. ...
3
votes
2answers
121 views

Which hydroxyl from either the phosphate or the glycerol is taken during synthesis of a phospholipid head?

The oxygen anion in the phosphate group is likely to be bonded with a hydrogen cation and thus forming a hydroxyl. When the phosphate group is condensed with glycerol to make a phospholipid, is the ...
2
votes
1answer
87 views

Are there known 3- or 4-nucleotide RNA linkers with no RE sites?

Question is rather self-explanatory. I'm looking for a non-cleavable RNA sequence to act as an RNA linker. I mention 3- or 4-nucleotides only, but making such a sequence with 2 nucleotides is rather ...
2
votes
2answers
326 views

Do brain cells shrink during REM sleep or a lucid dream?

In this BBC news article a study shows that during sleep brain cells shrink to open up the gaps between neurons and allow fluid to wash the brain clean. But do the cells shrink and undergo the whole ...
0
votes
1answer
188 views

What is meant by 73 hour birth [closed]

I was reading an article, when I read a sentence saying, His mother ... nearly died less than three years later during Mathers' 73-hour birth. What does mean by 73-hour birth?
0
votes
1answer
45 views

Reassociation of DNA

What is the order in which this DNA samples would would reassociate ? e.coli DNA plasmid DNA viral DNA satellite DNA DNA-RNA hybrid This is a homework question and I have not been given any ...
3
votes
3answers
374 views

Bioinformatics tool for “pairwise alignment” of complementary sequences?

I'm currently working on some ribozyme binding, and I'm looking for a tool that will essentially analyze the regions of the degree of complementarity in two sequences in order to extrapolate ...
2
votes
0answers
78 views

A number of questions regarding chemotaxis assay using PBMCs

In our lab we would like to study the chemotaxis of PBMCs towards conditioned medium obtained following treatment of cancer cells with different compounds. My questions are regarding the method of ...
2
votes
2answers
139 views

Sources for common laboratory Saccharomyces strains?

I'm used to working with bacteria - some of the more common laboratory strains sometimes come with an order from some vendors. What's the most convenient source to order common straings of ...
1
vote
0answers
25 views

How is saltatory conduction faster than conduction of unmyelinated fibers? [duplicate]

It's always the same explanation that currents are able to "hop" along Ranvier nodes instead of passing continuously along the axon making saltatory conduction more efficient than continuous ...
4
votes
2answers
76 views

Transmission of disease from mother to fetus

Can parasite, microbes be passed from mother to fetus through the placenta ? I know some like HIV can be.
1
vote
1answer
94 views

Detecting UV by humans

From my experience humans can detect UV - not by seeing it but by pain in their eyes. Many people (me too) feel pain when looking at UV lamps. When looking at sun through clouds I still can feel pain ...
2
votes
1answer
103 views

.Net DNA/Codon Parser

Does anyone know of an .NET (C#,VB.NET, maybe F#) DNA parser? If not I will probably make one, it doesn't seem like it would be hard. My general idea was to generate something that would report the ...
3
votes
3answers
75 views

Can genes that activate transcription factors also called be called transcription factors?

If the sole known function of a gene is to activate a transcription factor, would that gene also be considered a transcription factor, or is there a word for such genes that are further upstream on ...
0
votes
1answer
40 views

Cellular components of blood cells

There are different types of blood cells in the human body i.e. red blood cells, neutrophils, basophils, eosinophils, monocytes, T-cells, B-cells. What are the cellular components of these cells? ...
3
votes
1answer
396 views

What is needed for a G-matrix?

I have been doing a lot of reading on quantitative genetics and the G- (and B-) matrix lately. I get the principle behind performing the analysis now but I am still not sure how to do it. I'd like to ...
4
votes
1answer
2k views

Difference between mutation and DNA damage

What is the strict difference between mutation and DNA damage? As far as I understand it, a mutation is an alteration in the genetic sequence, having "tricked" the repairing machinery and thus ...
1
vote
1answer
64 views

What is the strength of human cornea?

What is the difference of pressure a human eyeball cornea (cornea, lens and other elements separating vitreous body from air) can handle? Or asking differently: what the outside pressure should be to ...
2
votes
2answers
79 views

Termination of translation

What dissociates first - the last tRNA, mRNA and release factors or the subunits of ribosomes? I tried searching this from Lehninger but couldn't get a clean answer.
0
votes
1answer
114 views

cellular respiration

What are the effects of addition of these chemicals to actively respiring cells ? Which of them would lead to INHIBITION of aerobic respiration ? Would cytochromes be actually taken up by cells ? ...
5
votes
1answer
51 views

Calling for Free Online Data for Paediatric ECG?

I need free online data about heart murmurs to study these: heart murmur frequency , S2 heart sound frequency and its split, murmur timing, and duration, murmur intensity, S3 sound presence and ...
0
votes
2answers
133 views

Won't natural selection miss the overall minimum of a function?

Suppose we have a population of about 1000 with an environment that does not change a lot (e.g. the atmosphere is more or less the same) and we leave this population to evolve. From what I understand ...
1
vote
1answer
135 views

Why do I have a lot in common with my mother? [closed]

I have not spoken to my mother in 15 years but recently connected with her and her side of the family. I was primarily raised in a different sub-culture after the age of 4. As it turns out I ...
-1
votes
1answer
103 views

What are uses of fossils? [closed]

What are the geological uses of fossils and how could it be utilised? From The Institute for Creation Science: Fossils are typically found in sedimentary rock, almost all of which were originally ...
5
votes
1answer
67 views

Shade-loving Plants

In shade-loving plants, the light compensation point is reached at low irradiance because: A. Leaves have more chlorophyll per reaction center B. These plants have greatly reduced respiration rates ...
2
votes
1answer
59 views

Antibody production in secondary immune response

Can IgG antibodies be produced in the secondary immune response without the help of T cells? Is the affinity of antibody for antigens higher during secondary immune response?
6
votes
2answers
322 views

Why are humans and almost every species on earth symmetrical?

I admit I'm not very learned on the subject of evolution, I just started researching it for myself about a week ago. One of the things that I don't understand is why humans and almost every other ...
9
votes
2answers
10k views

Blood Pressure: Significance of difference between systolic and diastolic

I wanted to understand what is the difference between systolic and diastolic readings of blood pressure. I understand 120-80 to about 100-60 is considered normal but does the difference in the two ...
3
votes
1answer
159 views

Number of genes required to sustain life

Are there estimates of the minimum number of genes required to sustain life? In what I mean by life here, I don't include viruses.
3
votes
2answers
2k views

Presence of MHC on red blood cells

Do red blood cells have no MHC? (I have often heard that they do not.) If so why are they not destroyed by immune cells?
3
votes
1answer
63 views

Alternating Ovulation

I have often heard that right and left ovaries alternate in releasing ovum. Is it always true? What controls this rhythm? Is it simply because the other ovary is unresponsive to LH or FSH? If so, ...
6
votes
2answers
3k views

When designing primers how important is the GC clamp?

I'm designing a set of primers and reading about the principles of primer design one of which is: GC Clamp: The presence of G or C bases within the last five bases from the 3' end of primers (GC ...
4
votes
1answer
42 views

What are the molecular mechanisms that make the turtle brain more resistant to hypoxia?

I know that turtle brains, particularly those of individual species that hibernate and burrow are particularly resilient to hypoxia and any tissue damage secondary to a hypoxic event. What are the ...
4
votes
2answers
632 views

What is a “pure odorant”?

This article about testing for Alzheimer's, via changes in the ability to smell, said: She thought of peanut butter because, she said, it is a “pure odorant” that is only detected by the ...
2
votes
0answers
93 views

What to do with a DNA sequencer? [closed]

My school is very fortunate to have a DNA sequencer, and I want to find an opportunity to learn how to use it. I'm currently taking AP Biology this year, and I hope to do an independent study in ...
7
votes
1answer
242 views

Cytoplasmic determinants - protostomes and deuterostomes

Cytoplasmic determinants are spread unevenly in the egg, and so when embryo starts forming (cells start dividing), the determinants are also unequally divided between cell. This unequal distribution ...
1
vote
1answer
113 views

Creative ways to deactivate alpha-amylase taken from fungi

I can deactivate $\alpha$-amylase in ways such as extreme temperature controls, pH controls of the solution it stays in, or adding salt to the solution. However, are there any other unique or ...
4
votes
2answers
4k views

Why do ladybugs have a different number of points on their backs

Everytime I see a ladybug I ask myself this question. Why does every ladybug have a different amount of points on its back? Is it because of its age? Or because of its genes? Is it inheritable?
4
votes
1answer
119 views

Does the body lose energy or gain energy relatively when drinking or eating hot things?

Does the body lose or gain energy when drinking or eating hot things compared to more neutral temperature things? On the one hand, The body could somehow convert the heat energy into human usable ...
4
votes
2answers
116 views

Why don't amino acids get linked in the functional groups of acidic and basic amino acids?

There are 'acidic' and 'basic' amino acids like aspartate and histidine. When protein is synthesized with those amino acids, what ensures that the to-be-assembled amino acids will not bond to the ...
1
vote
2answers
117 views

Would it be correct to state that any biological difference between the sexes has to be found in the Y chromosome?

If the reason Why Men Don't Listen and Women Can't Read Maps is genetic, then one of the genes in the Y chromosome is to blame and in theory could be identified. Correct or incorrect?
-6
votes
2answers
229 views

Is love biologically useful? [closed]

I thought about this statement a while ago: Natural selection sucks, it says those who love too much (or too many) will die the easiest and fastest. Sad but true. Only family (biologically of ...

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