11
votes
1answer
756 views

How does evolution produce complex organs

I've been wondering lately how evolution manages to produce complex organs. It is pretty obvious to me how evolution would select some minor traits like size, resistnce to illness or climate. There is ...
8
votes
3answers
973 views

If body temperature is 37°C (98.6°F), why are most people more comfortable at around 21°C (70°F)?

It may be different for other people, but for me, anything above 32°C (90°F) is very uncomfortable, and my body is inclined to seek cooler temperatures. But I would think that at 32°C, the body would ...
1
vote
0answers
176 views

How do optical illusions work? [closed]

Hello fellow investigators I have two questions about optical illusions 1) A photo mosaic is something like this http://i.stack.imgur.com/Pzplp.png What are the optical principles behind our eye ...
6
votes
1answer
354 views

How and when did a dedicated immune system evolve?

I have recently been doing a lot of research into the interplay between the innate and adaptive immune systems in humans, and mammalian laboratory models. This has led to my reading some interesting ...
2
votes
0answers
62 views

Are there any situations in which phenylephrine is preferred to pseudoephedrine?

In the mid 2000s in the US, due to issues of drug enforcement, pseudoephedrine containing medications were brought behind the pharmacy counter and in most cases require ID, and phenylephrine was ...
6
votes
1answer
123 views

Genetic Diversity and Adaptation

I am somewhat new to evolutionary biology, having studied it on my free time as a computer science student. There is one particular thing that has always bothered me for which I have not seen a good ...
10
votes
2answers
172 views

How did the nucleobases in the Murchison meteorite form?

The Murchison meteorite is an important piece of evidence for abiogenesis, because it contained nucleobases from extraterrestrial origin, as this Wikipedia article explains. These results ...
5
votes
2answers
510 views

Why insects are so energy-efficient while flying?

Why are insects so energy-efficient while flying? Is it because of their light weight and aerodynamics or due to very efficient biochemical transformations (food->energy)?
2
votes
2answers
149 views

Do the simplest bacteria have ribosomes and helicase?

I find it interesting that all life on earth use DNA. I've seen video on how helicase and ribosomes work together to copy DNA sequences (to RNA) with helicase then recreate them using ribosomes. Does ...
8
votes
3answers
9k views

Why can't the brain and red blood cells use fuels other than glucose?

The question is rather straight forward: I have always been curious as to why, but cannot find an explanation online. I can imagine that the mechanism is different for each, but why does brain tissue ...
15
votes
2answers
3k views

Why is glucose our primary source of energy?

Is there any evolutionary reason for glucose being the "main" molecule used as a source of energy, beginning with glycolysis and subsequently cellular respiration (after being converted to two ...
10
votes
1answer
148 views

Does stress physically age our body?

Going by the assumption that stress eventually triggers a flight/fight response, and the subsequent realization that flight/fight puts the body in a system of readiness to use it's available resources ...
3
votes
7answers
380 views

Introductory books about evolution

This days I read some debates on evolution. That made me more interested to read something reliable on topic - I mean books. I'm christian - although I think it doesn't matter on that topic - and I ...
7
votes
1answer
58 views

Sequence of ribosomal RNA

Is it possible to sequence rRNA directly, that is, using the ribosome rather than the DNA from the nucleus? For example, this paper, Complete nucleotide sequence of a 16s rRNA gene from E. coli, ...
4
votes
0answers
164 views

How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?

I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II). Is there any difference in the degree to which these ...
5
votes
2answers
171 views

Why is the human body able to repair a broken bone and not a heart muscle?

The human body can repair skin/organ laceration, fractures, even repair nerves - albeit the duration and rate of recovery differ. For instance: The burn scar on my arm from the hot soldering iron ...
1
vote
0answers
22 views

Are open grounds in the vicinity of new construction more prone to waterlogging? [closed]

In my experience as open grounds are paved over by new concrete work other grounds yet open are proportionately more water-logged after heavy rain. Over time trees in such water logged grounds too die ...
7
votes
1answer
107 views

How does Yeast-two-hybrid detect interactions between several proteins in one experiment?

I am trying to understand the Y2H screening method. I can understand how we can check if two specific proteins interact with each other. For example, if we want to check whether protein A and protein ...
4
votes
2answers
188 views

What is the proper quick freezing /snap freezing protocol for pancreatic tissue?

I would like to do a quick freeze on pancreas from mice. I want to then make sections (30 µm thick). The idea is to preserve a fluorescent staining done in vivo. I do not know if I should place my ...
3
votes
1answer
81 views

Predictable microchimerism

I read in New Scientist recently that microchimerism occurs between previously born siblings and grandparents, not just the mother. Do we know which parts of the genome are likely to be transferred? ...
3
votes
2answers
172 views

How do I create a probe for in situ hybridization?

I tried to make the probe several times but it failed again and again. It usually turns out that the probe after hydrolysis is very very short (maybe around 50nt). I did not check the RNA before ...
4
votes
1answer
343 views

Lifespan of connective tissue cells

This post is regarding a follow up on my initial post on "Properties and life cycle of chondrocytes and tenocytes". I am elaborating on my question on the lifespan of tenocytes and chondrocytes. ...
6
votes
2answers
177 views

Intrinsic apoptosis in erythrocytes

With a lack of mitochondria, can red blood cells perform intrinsic apoptosis and do they have another way of generating cytochrome c to attach to a CARD domain and assemble the apoptosome? Or are ...
10
votes
1answer
88 views

Are rods/cones rejuvenated periodically?

Pretty much what the title states. Some cells/structures in the human body undergo rejuvenation periodically by flushing away older cells and growth of new ones. E.g Skin, Blood Does this (for want ...
3
votes
2answers
258 views

JMol “calculate HBONDS”: which atom is the donor/acceptor?

JMol can be used to identify Hydrogen bonds in proteins by the script "calculate HBONDS". By outputting the state of the network, we can obtain a lisdt of H-bonds. Here's one line from an example ...
3
votes
1answer
68 views

What's in a Name: Statistical Genetics

The novice often performs population calculations using what is referred to as Mendelian Genetics. Soon after the publication of Mendel's results; Hardy and Weinberg presented their results after the ...
4
votes
0answers
51 views

Does a mydriatic drug neutralize the action of a miotic?

If a person were administered a mydriatic, would the subsequent application of a miotic neutralize the action of the former? If the sequence were reversed would a mydriatic neutralize the effect of a ...
10
votes
2answers
163 views

Is there an “evolutionary species similarity calculator”?

Is there a website where I can input pairs of species and get an "evolutionary similarity score"? E.g. (numbers are completely made up) Input: Chimp and Human, Output: 97% Input: Cat and Human, ...
3
votes
1answer
147 views

Negative feedback in the fructose metabolism in liver

What happens in liver when large amount of fructose is consumed? I vaguely remember my biochemistry lecturer telling us that the enzymes that process fructose in the liver does not have negative ...
9
votes
1answer
141 views

Protein data bank syntax: Can two protein secondary structures “overlap”?

I have a technical question regarding the syntax in Protein Data Bank files. In the protein with PDB# 1AE9 (pdb file), there are two lines in the .pdb file: ...
2
votes
1answer
1k views

What is the “lifecycle” of an average eschar and what types of cells are involved in each stage?

(after some deliberation in the comments, I've decided to make the question more general) An eschar or "dry scab" often forms at a site of injury over a large cut or sore. It seems as though the ...
9
votes
2answers
132 views

Does artificial high intensity light damage permanently dark ecosystems?

Popular science features on wildlife typically capture camera images using natural light, or high-speed exposures. This is not possible where the ambient light is extremely poor. E.g. Caves, Undersea ...
1
vote
1answer
896 views

Does cockroach lay eggs in human flesh when they “bite”?

Recently, i have "bite" by cockroach, not only the "bitten" area red and swallowing, and more specificly, it have a big hole in that area, when i clean it with hydrogen peroxide solution, something is ...
4
votes
1answer
157 views

Why would deers keep crossing a river full of crocodiles while some of them have been killed?

I recently watched a clip on Discovery Channel, where I saw deers crossing a river full of crocodiles, ignoring the fact that some of them would have been killed doing so. What could be an ...
0
votes
2answers
257 views

Do cockroaches have less health issues than humans?

Cockroaches are known to live in very dirty places like sewers. Does this cause them to evolve to be stronger against parasites and bacteria? Recently I read online that cockroaches can sustain ...
4
votes
1answer
73 views

What are possible health risks to women having large numbers of children?

What is the possible health issue the women would face in this record? The record for most children born to a single couple belongs to the first wife of Feodor Vassilyev of Russia. In 27 ...
9
votes
2answers
423 views

Which bacteria have the highest mutation rate?

From my reading on M. tuberculosis, I know that this organism has a pretty high mutation rate due to uncorrected sloppy replication, which leads to a high rate of development of spontaneous resistance ...
7
votes
1answer
351 views

Can I image Coomassie and GFP in gels at the same time with a fluorescence scanner?

I'm working with a GFP-tagged protein and am routinely using a fluorescence imager (GE Typhoon) and a standard optical scanner to capture fluorescent and absorption images, respectively, of my ...
13
votes
1answer
715 views

Are human bodies programmed to die?

Following from this question: What is the evolutionary advantage of death?: Is there any evidence that human bodies have systemic self-destruction built into their developmental program? I'm not ...
5
votes
1answer
298 views

Aren't antibiotic resistant probiotics dangerous?

Multidrug resistant probiotics are often recommended by doctors in various cases. But since bacteriae can easily exchange genes by conjugation or other means they could promote the drug resistance of ...
18
votes
2answers
1k views

Can rats pass on memories of a maze to their offspring?

A friend of mine told me once about a documentary movie he saw some years ago. On this movie he saw scientists talking about particular experiment. This experiment involved rats and probably ...
17
votes
4answers
2k views

Why are there exactly four nucleobases in DNA?

Does someone know why DNA is composed of four nucleobases? In particular, is there an explanation for the number? Why four and not two, or eight?
4
votes
2answers
6k views

Calculating Protein Concentration from Kilo Units (KU)

I am looking to purchase Pyruvate Kinase from the Sigma Website, they state the volume in Kilo Units (KU) i.e. 1, 5 or 25 KU. It also states there are 350-600 units / mg protein. Does this mean one ...
6
votes
1answer
178 views

Is there a detectable amount of bacterial DNA in the blood of infected persons?

With which bacterial infection in humans has it been shown that bacterial DNA can be found in the blood? If any is found it is likely not to be very much, and even difficult to distinguish from ...
3
votes
1answer
1k views

SPINAL CORD: Do the axons from white matter synapse with the cell bodies in grey matter?

After wading through a sea of information, I understand the main differences between the white matter and grey matter of the spinal cord. I know that white matter contains myelinated axons in the ...
4
votes
1answer
626 views

Is ovum + ovum fertilization possible for human?

In humans is it possible to fertilize a ovum with another ovum from the same female subject? I already found some works in which the ovum is fertilized by a somatic cell (see e.g. this ), but I am ...
4
votes
0answers
65 views

effect of background selection on promoter regions compared to distant enhancers?

Has anyone looked at the effect of background selection on the levels of conservation of promoter regions compared to distant enhancers? Do promoter regions have a higher conservation due to ...
9
votes
1answer
3k views

When running gels what is the difference between constant volts or constant amps?

In general, you want to be consistent with running your gels either at constant volts or constant amps. However, it is very clear that during the progression of both PAGE and agarose gels, the free ...
6
votes
1answer
316 views

Photosynthetic Pigments vs. Chloroplasts

What is the difference between Photosynthetic Pigments and Chloroplasts? I know plants have both but Prokaryotes (Bacteria and Archeae) only have the former.
6
votes
2answers
419 views

What is the relationship between migraines and histamine?

A family member suffers from migraines so I have been reading a little around the subject. There seem to be any number of "triggers", but I have seen mention several times of the role of histamine ...

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