3
votes
1answer
57 views

Proving time travel

Consider this answer to an interesting question. It's not possible to prove completely that someone is the descendant of someone else, there's always a nonzero probability that the results are a ...
-1
votes
0answers
5 views

Sister replacement with female mates?

I have a bad relationship with my sister and I often grow obsessed toward selective females from time-to-time. Often I notice that these obsessions have no sexual desires; I do not feel a need to have ...
1
vote
1answer
10 views

Does suffocation pain involve nociceptors?

I never suffocated myself so not entirely sure, but when you suffocate, it's painful, right? But of course different kind of pain than being injured or sick. What I'm wondering is, if the "painful" ...
0
votes
0answers
3 views

Reliability of Sanger sequencing

Hailed as the "gold standard" of sequencing, I was wondering to what Sanger sequencing owes its incredible accuracy to. If possible, I would like a quantification of the accuracy (because I doubt it ...
0
votes
1answer
8 views

Stop codons and exons?

If we had a hypotheical gene called gene exampleGene and this gene had 5 exons, labeled A, B, C, D, and E in that order on the chromosome, could it be the case that the stop codon for this gene be on ...
1
vote
0answers
9 views

Neuroscience of mathematicians

I've tried to google this but everything that comes up are things like "mathematical neuroscience" rather than the other way around. Specifically, I'm interested in anything we currently know about ...
4
votes
1answer
29 views

What is this insect? Found in Peru

I took the pictures today in Cusco Peru. It is the third insect of its class in a month. I never see it before. I thought that it is a wasp, but I think it's really thin to be a wasp. It's about 4 or ...
1
vote
0answers
8 views

How did the introduction of artificial light changed the life cycle of a plant?

Plants in urbanized areas are constantly exposed to artificial light after sunset. In their natural habitat there is a more distinct day and night cycle. Since light is an important factor in a plant ...
-1
votes
1answer
17 views

Which protein complex is composed of the greatest number of different kinds of proteins, and how many types are involved? [on hold]

Why are some protein complexes composed of many different types of proteins? How many different types are they composed of? In particular, which protein complex has the greater number of different ...
6
votes
2answers
77 views

Latency differences between our senses

I would be interested in knowing how long it takes between the moment something touches our skin and the moment something is activated in the brain. Also how long does it take in total until we ...
4
votes
2answers
93 views

I have a black tiny bug crawling all over the house

This bug is crawling all around the house it stays within the shadows and moves very very slow, i have never seen it jump or run, it just moves very slowly P.S. those bugs as u can see are smaller ...
2
votes
1answer
14 views

Is it in principle possible to revive an extinct species having no living relatives?

Is it, in principle, possible to revive an extinct species having no living close relatives but whose DNA and other tissues have been preserved? What about the case where there are no living ...
5
votes
4answers
2k views

What is the relationship between sexual and and natural selection?

In http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12701.html, they say: Thus, it seems that the diverse coloration in this species is promoted by both natural and sexual selection. ...
1
vote
1answer
42 views

Why is it important to study chromatin to understand cancer?

Many labs and many projects in biology institutes and university departments have been starting to study chromatin. Chromatin states, chromatin interactions, chromatin loopings, chromatin behaviours, ...
7
votes
5answers
320 views

Book/source for learning bioinformatics, focused on genomics?

Does anyone know of sources for learning bioinformatics, focused on genomics? I would like to learn alot of skills I could apply potently in the workforce if I ever became adept at the fields. My ...
1
vote
1answer
25 views

What is genodiversity good for?

I saw some documents which were trying to say that they can prove via sweat smell selected by women that humans are developed to find a partner with similar genes. At the first glance, I refused it as ...
-2
votes
1answer
28 views

What is a new biotechnology issue? [on hold]

I'm looking for any new biotechnology issue related to Biochemistry, Metabolic processes, molecular Genetics, or other relevant fields. If anyone knows of an issue that has solid resources around I'd ...
0
votes
0answers
22 views

How long has to be DNA? [on hold]

We have learned that the same information are saved in the DNA in the same place. So when DNA split and connect again (while reproduction), it has to fill into the atom-exact place?
2
votes
1answer
41 views

How long do the periods of systole and diastole last?

The background to this is i'm doing some work using ECGs for an animation of the heart and i'm having trouble defining the end points of these periods, particularly diastole. Currently, the only ...
1
vote
1answer
18 views

What is the connection between exercise and muscle growth

From a physiological perspective, all that is done during exercise is the expending of energy in the form of ATP to fuel muscle contraction and extension. When I looked up why muscle grow due to ...
1
vote
1answer
15 views

Are more molecules of ADP than inorganic phosphate returned to the light reaction in photosynthesis?

During the dark reaction, 9 molecules of ATP are consumed for every 3 carbon dioxide molecules, yet only 6 molecules of inorganic phosphate ultimately leave the cycle. Does that mean that there is a ...
3
votes
1answer
64 views

Involuntary twitches and apnoea during early phases of sleep

I assume most people either experienced or have seen people with the following phenomenon: in the early phases of sleep sometimes involuntary twitches occur that usually accompany the pause of ...
6
votes
1answer
91 views

How well do we notice asynchronicity?

I'm stopped at a stoplight and, with nothing to do, my thoughts wander to the timed don't-walk sign that governs any pedestrians who might wish to cross the street I'm driving along. I can see two ...
-2
votes
0answers
11 views

Spring turnover in lake

During spring, the water at the top is at 0 degrees, and that the bottom is at 4 degrees (with a small middle part in between with intermediate temperatures). In spring as water warms at the top, its ...
3
votes
2answers
49 views

Are there human cells, apart from red blood cells and platelets, without a nucleus?

I know that blood platelets and erythrocytes do not have a nucleus. Are there more cells in the human body without a nucleus, such as pancreas, cartilage, or lung cells?
5
votes
1answer
192 views

Biological origin of shuddering during sleep

What is the biological origin of the following behavior: Sometimes, during the early, formative phase of sleep (when you have a gradually dimming consciousness of what all is happening around), you ...
4
votes
1answer
52 views

When is Water Produced During Photosynthesis?

The formula for photosynthesis is: $$6CO_2+12H_2O \rightarrow C_6H_{12}O_6+6O_2+6H_2O$$ I can count the carbons, the waters on the reactant side, the oxygens, and the glucose, but I cannot seem to ...
0
votes
0answers
16 views

Why do fingers swell during winters? [on hold]

Why do fingers swell during winters (of temperature 5-15 degree celsius)? During winters mine and many others's fingers swell. is it due to blood circulation or what?
2
votes
1answer
24 views

How Does NADPH Reduce 1,3-BPG?

If NADPH returns to being NADP+, then that means one proton and two electrons have been incorporated into 1,3-BPG. If only one proton and one electron were attached to the carbon in 1,3-BPG (removing ...
3
votes
1answer
21 views

Quantitative Trait Locus process?

I do not seem to understand the concept of Quantitative Trait Loci(QTL's), can anyone explain it to me in detail? Reading the wikipedia article helped somewhat, but I do not understand it well. What ...
2
votes
1answer
43 views

Modeling inclusive fitness

Consider a population of two altruist with coefficient of relatedness $r$. The average inclusive fitness of this population will be $w_{0} + br -c$. Like in this example, assignment of inclusive ...
1
vote
0answers
12 views

Why do flagella form a bundle only when they rotate counterclockwise during chemotaxis?

During Chemotaxis in bacteria with flagella, the flagellar rotation dictates how the cell moves. If the flagella rotate counterclockwise, then they form a bundle at one end of the cell (---O) and ...
2
votes
1answer
111 views

Does enzyme Km comparisons make sense?

I have encountered comparisons of the Michaelis-menton constant (Km) a few times. Generally speaking if Km of an enzyme is higher, then it's affinity to its substrate is lower. How does this make ...
0
votes
0answers
31 views

Protein Folding [on hold]

I am planning to do my Masters thesis in Biophysics in the topic of "Thermodynamics of Protein folding " It would be great help if anyone could suggest me the proper way to start with like which ...
3
votes
1answer
36 views

How can we create a living dinosaur using DNA technology?

I'm wondering what would we need to do to create a living dinosaur using DNA technology? If it is not possible with current technology, will it ever be feasible? In the movie Jurassic Park, ...
-2
votes
1answer
24 views

Standard DNA extraction protocol [on hold]

Which DNA extraction protocol in plant and other biological complex is acceptable method for article?
0
votes
1answer
21 views

Does the term “upper extremity” include hands?

I see on http://en.wikipedia.org/wiki/Upper_limb that the term "upper extremity" seem to include hands. However, in many hospitals, there is a "Hand & Upper Extremity Service", which would tend to ...
3
votes
1answer
27 views

Analyse a ECG graph

I have a project about extracting features from a homemade ECG. I need PQRST points from the heart beat. The ECG I'm using have 3 electrodes that attaches to the chest. The problem is I don't know ...
8
votes
1answer
36 views

When do plasmids replicate relative to its host cell cycle?

For plasmids is so much shorter than their host cell's genome (about 1/1000 in my case), it will take only 1/1000 time for it to replicate. With respect to cell cycle, when will that replication ...
7
votes
4answers
230 views
+50

Introductory biology text for an outsider

I'm a maths major and I have an interest in learning biology. I know very, very little; I know how babies are made and that's about it. Could anyone recommend a stimulating text to read for it's own ...
3
votes
1answer
99 views

How does rate of evolution/innovation scale with population size?

I understand that there will be many other factors that affect rate of evolution/innovation. However, other things being equal, how will the rate of evolution vary between two populations of different ...
3
votes
0answers
24 views

What is this frog?

(Man, there's a lot of 'What is this X?' questions here...) I saw this while walking in Cyprus in early April. It was at about 100m altitude, in woodlands, sitting in the sun on a concrete step ...
1
vote
0answers
45 views

Where can I find mutation datasets for cancer (other than TCGA)?

My lab has been using TCGA data (somatic mutations and clinical data) to develop panels of genes and of mutations we expect to see in certain cancer populations. We'd like to validate our panels by ...
2
votes
1answer
239 views

Using RNA-seq to compare gene expression across patients instead of between Control and Experimental conditions

I am working with RNA-seq data from the Cancer Genome Atlas TCGA and I have been reading about how people have compared gene expression levels measured by RNA-seq. Many of the papers I have read talk ...
3
votes
1answer
41 views

Classify chemotherapy drugs?

I'm studying a TCGA dataset trying to find correlations between gene expression and clinical data which might shed light on some pathways. One column of the clinical data provides a list of ...
3
votes
1answer
41 views

Why do some proteins “use” a beta barrel structure instead of alpha helices in transmembrane space?

Most proteins are fixed in the membrane by alpha helices. But some use beta barrels. Wikipedia describes beta barrels as used for porins, preprotein translocases, and lipocalins. To me, a coiled coil ...
0
votes
1answer
463 views

TCGA data, and bioinformatics design questions for SNP/ mirna analysis

It's my first time posting to this forum but was looking for some help on the data aspects of this project. My tools of choice would be in python/R . Goal: I'm looking to create a disease specific ...
2
votes
0answers
92 views

Best way to automatically link Gene Entrez ID with Gene Symbol in TCGA

I am trying to figure out how to link Gene Entrez ID with Gene Symbol, for TCGA dataset. So far, I have found this ftp directory with Gene info updated daily. But, for Entrez ID 728661, I have found ...
1
vote
1answer
248 views

Mapping a mutation to known SNP, 3' UTR, miR

I've parsed out a very large TCGA cancer ssm (single mutation file) file to give me the essential information. The ssm is in the following format: ...
0
votes
1answer
85 views

How to select genes before log2 ratio on a RNASeq gene expression matrix, based on signal median

I want to transform a TCGA mRNA expression matrix (in linear data format) to log2-ratios and then run a feature (gene) selection, selecting the 1000 most variant genes (genes with higher standard ...

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