0
votes
1answer
27 views

Specialist evaluation for people aged under 40 years with stage 1 hypertension

Reading the NICE clinical guideline for Hypertension it says... For people aged under 40 years with stage 1 hypertension and no evidence of target organ damage, cardiovascular disease, renal ...
1
vote
1answer
15 views

Is ingestion of your own faeces dangerous?

Avoiding contamination of the environment by human faeces has been a big part of the health improvements we've seen (in the Western world) over the last few centuries, but my understanding is that ...
1
vote
1answer
26 views

Is there a rule for the annotation of the basepair or gene locus origin in bacterial genomes?

Since all bacteria have one circular chromosome, there is no designated origin to start the systematic gene locus numbering. Therefore, what is the rule to start the numbering at a particular point ...
4
votes
0answers
9 views

Why do humans hear better between 2kHz and 5kHz?

I've recently seen the following image: Source: https://commons.wikimedia.org/wiki/File:Hoerflaeche.svg Translation (from German): The upper boundary (Schmerzgrenze) is where it starts to hurt ...
2
votes
0answers
5 views

Can anyone identify this chrysalis?

It's about 5 or 6 cm long. It's on the outside (north facing) wall of my garage about a metre above ground level. Photo taken in Thailand near Hua Hin (about 12N 100E) in December 2014.
4
votes
2answers
87 views

positive and negative feedback

I want to know more about positive feedback in gene regulation and to know the similarity and differences between positive and negative feedbacks.
7
votes
2answers
77 views
+50

Skin porosity in glans penis when erect

(Apologies if this is a too weird/inappropriate question in this forum. I only thought that I ask it since it happens to be part of human life.) The skin on a human typically blocks many substances ...
-1
votes
0answers
17 views

What is the ratio of air to flesh inside a live clam's shell?

Is a live clam's shell completely filled with flesh or is there some air/water in it? If so how much water/air is there in comparison to flesh? I'm curious if the density of a clam changes through ...
4
votes
2answers
198 views

How is membrane capacitance related to the increased speed of saltatory conduction?

Here is the original question which inspired my question. As explained by the answers there, the reason saltatory conduction in myelinated neurons is faster than non-myelinated conduction is because ...
2
votes
3answers
32 views

Long term storage of agarose-ethidium bromide gels that have already been cast

I have come up with what I thought was a clever idea: Store the agarose gels I pour, and only cut as many lanes as I need to run later, minimizing wasted agarose (and wasted effort/time) when I need ...
0
votes
0answers
4 views

Coniferous trees in temperare rain forests

In temperate rainforest, the dominant plant form is often coniferous trees (source). However, coniferous trees are also the dominant plant form in a very different climate and form a different biome ...
-3
votes
0answers
28 views

Transparent watery fluid [on hold]

What is that transparent fluid coming from the tips of finger when skin is peeled off ? Is that actually lymph ? Can I see my lymph ?
4
votes
1answer
20 views

Can the eye distinguish between pure and composite colours and how do we measure this?

Red light plus green light makes yellow light. Suppose I shone a pure red light, say 650nm, onto the same spot as a pure green light, say 550nm. The eye sees this two-peak spectrum as yellow. This ...
2
votes
3answers
92 views

fastq-dump using mkfifo to stream data

So, fastq-dump has the ability to be run on just an SRA file accession number, such that the SRA is converted to FASTQ on-the-fly, and the SRA doesn't have to be written to disk. I'm curious whether ...
9
votes
2answers
166 views

Did Darwin ever reach the conclusion that selection will remove variation?

According to simple models of selection the genetic variance in a population should be reduced by selection. (Fisher's fundamental theorem states that the rate at which a population can evolve is ...
2
votes
2answers
36 views

Choosing appropriate statistical test for ordinal data

Ordinal response variables show up often in biology, but I'm not sure how they are best analysed. Some examples are qualitative assessments (little, many, a lot) or risk assessments (low risk, medium ...
2
votes
2answers
28 views

Action potential changes in low sodium concentrations but constant osmotic pressure

If I bathe a squid axon in a fluid that has high sodium concentration , why does the duration of action potential decrease compared to a control experiment in low sodium bath but maintained at the ...
7
votes
3answers
45 views

Evolution: One big population vs. many small populations

Let's say I want to evolve a bacterium that is resistant to an antibiotic. I want to do this by growing initially clonal populations of bacteria in presence of this antibiotic for a long time. I have ...
0
votes
0answers
21 views

How do I import FASTA files into Haploview?

I'm trying to produce a haplotype network and so have decided to use the software haploview. However I'm having some problems importing my sequences into the software. I Have my sequences in a FASTA ...
8
votes
1answer
49 views

Mass spectrometry versus western blotting for validation

I have mass spectrometry data (LC-MS/MS) from rat cortices under either drug or control treatments. The results were performed in triplicate (three pairs of rats, drug or control per pair). In ...
1
vote
3answers
149 views

Can human brain memory be removed by EMP?

The human brain is the most complicated human organ so it is hard to examine it completely but based on what we know do you think (or do you know from some source) if a human memory can be removed by ...
-1
votes
0answers
9 views

How does extreme skewing of inactivation of X in heterogeneous mothers affects X-linked phenotype expression in sons? [on hold]

I am particularly interested if there is differences in phenotype insensitivity in X-linked phenotype when: 1. Heterogeneous mother has mutated X inactivated (through extreme skewing of inactivation) ...
1
vote
1answer
35 views

Deciduous trees in tropical rainforest

Some books says the dominant plant form in tropical rainforest biome is broad leaved evergreen trees. Other books say it is broad leaved evergreen trees and deciduous trees. What is the most accepted ...
-3
votes
0answers
20 views

Can apoptosis via high levels of capsaicin or resiniferatoxin aid in the destruction of viruses? [on hold]

A virus creates a barrier of proteins around it's host cell. Can high levels of capsaicin, or even resiniferatoxin be used to make virus infected cells self destruct for the purpose of possibly ...
3
votes
1answer
33 views

What is the purpose of segments in citrus fruit?

What is the purpose of segments in citrus fruit? In my experience, each segment usually contains from zero to two seeds. I may have seen more but only rarely, if I remember correctly. What is the ...
6
votes
2answers
144 views

Ni-NTA purification, problem with the chaperone protein

I'm trying to purify the protein by Ni-NTA affinity chromatography. It seems that my protein (size about 54 kDa) is co-purified with chaperone protein (probably GroEL - as the band is around 57kDa). ...
-3
votes
0answers
22 views

How is the protein removed from the DNA preparation? [on hold]

to determine how much DNA you have, you measure the absorption of the DNA.
7
votes
3answers
898 views

What is the science behind the inaccurate perception of colors?

If I go into a green room (all walls are semitransparent and green) and spend some time - around 10+ min - in there, when I come out all my eyes see is white as pink. I see no (or very few other) ...
0
votes
0answers
36 views

Immunotoxin to kill viral infections [on hold]

I have been working on a project about fragment antigen binding antibodies. I was researching on immunotoxins. Immunotoxins are basically toxins attached to antibodies so that when the antibody ...
1
vote
0answers
29 views

Persistency of botulinum toxin in environment

There is information about decontamination times here on pages 6 and 7. My specific question is how persistent botulinum toxin is in a natural environment, or alternatively, what is the half life of ...
8
votes
2answers
95 views

Is there any evolutionary advantage of selection of L-amino acid over D-amino acid?

After listening to a scientific talk, I had this question that why in the natural selection process, are the L-amino acids selected over the D- form. However, we still we produce D-amino acids; ...
7
votes
1answer
450 views

RNA seq and using of Poly(A) or non-Poly(A) based amplification of RNA

I'm studying "Deep sequencing the circadian and diurnal transcriptome of Drosophila brain" Hughes et al., 2012. I've got some problems with the materials and methods. Before RNAseq, the authors ...
1
vote
1answer
20 views

G>T transversion VS. T>G transversion?

So I'm reading about how mutations in DNA can be caused by oxidative damage. An example of a product of oxidative damage is given: 8-oxo-7-hydrodeoxyguanosine My textbook says that this product ...
1
vote
4answers
163 views

Why do some people find vegetables so repellent when evolutionarily they should find them an attractive and thus tasty food?

Why do certain people (especially kids) find vegetables so "repellent" when evolutionarily they should find them an attractive and thus tasty food? I ask this question because if Darwin's theory of ...
4
votes
1answer
29 views

What is the biggest facultative anaerobic metazoan known to science?

Related: What's the biggest obligate anaerobic organism discovered till now? I had always assumed that the Riftia tube worms were obligately anaerobic since they lived next to anoxic volcanic ...
1
vote
0answers
37 views

How do PER/CRY complexes accumulate in the cytoplasm?

The Period/Cryptochrome (PER/CRY) complex is a heterodimer that transcriptionally regulates circadian rhythm. When it is phosphorylated, it is transported to the nucleus and it inhibits a ...
2
votes
0answers
39 views

Are the Chromosomes organized in any meaningful way? [on hold]

So my major is in pharmacy but both my master and my (currently in progress) doctoral degree are both in theoretical chemistry. My thesis is about quantum chemistry and proteins, but it has a certain ...
8
votes
1answer
103 views

Neuroendocrinal mechanism of parturition

My book reads, "The fetus signals that it is mature by secreting certain hormones that diffuse across the placenta into mother's blood and cause the secretion of oxytocin from her posterior ...
4
votes
1answer
42 views

Is there any way the food industry can benefit from biofilms?

I realize all of the disadvantages, but I am wondering if the food industry can actually benefit from the formation of biofilms.
0
votes
1answer
31 views

STRING ID - allelic differences and splice variants

STRING has protein (amino acid sequences) mapped to a single gene ID. I have these doubts with respect to STRING ID. I find that 1.All alleles of a single gene share the same STRING ID and ...
5
votes
1answer
56 views

Are there baby drinks closer to breast-milk?

Many women cannot or will not feed their children with breast-milk. It is my understanding breast-milk has many advantages over formula. Some psychological like oxytocin and some physiological like ...
2
votes
0answers
46 views

Specific location where nerves converge

I'm looking for the "earliest" specific site where the 3 following nerves' sensory signals "converge": Trigeminal nerve Median nerve Superficial peroneal nerve By "earliest", I really mean the ...
5
votes
2answers
55 views

What does pain look like in wave form?

I am interested in understanding what "pain" and "hot/cold" look like, as far as waves signatures (signal processing) go. My general understanding of how pain (nociceptive pathways) and hot/cold ...
-3
votes
0answers
32 views

Could I be secretly left-handed? [on hold]

From a young age I have always used my right hand for tasks, leading to my 'right-handedness'. Currently I use my right hand for pretty much everything. But could this be simply due to habit? Today ...
-4
votes
1answer
48 views

Are transgenders born physically different from others?

Are all children born with only either male or female body parts (other than exceptions), or is there actually a natural third gender with the physical characteristics of both genders, e.g. the child ...
6
votes
1answer
190 views

What percentage of the (additive or not) genetic variance is explained by the 'n'- most important loci?

Standard models in population genetics look up at the evolution of few loci which impact fitness. The variance in fitness is determined by the genetic variance and the environmental variance (and the ...
6
votes
0answers
167 views

Additive genetic variance components from LMER in R

I've set up some dummy data in R which makes 40 genetically related lines, they are all siblings within a line so are genetically related by a factor of ½ thus additive genetic variance should be ...
17
votes
3answers
1k views

Hot water and bacteria

I know that it is common to say, "use hot water when washing your hands" or when you've got a cut, "wash your hands with warm water," etc. I was wondering, why is this the case? Since bacteria grow in ...
1
vote
0answers
27 views

Physiological markers of some antibiotic resistance and DNA? [on hold]

I am studying antibiotic resistance through DNA on Physiology. I am particularly interested its effect on Physiology: heart rate blood pressure pacemakers of the heart mean electrical axis ...

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