2
votes
1answer
53 views

Spinal cord injury bypass

When the spinal cord is damaged, the connection between the brain and some part of the body may be lost. To restore this connection, researches are considering either: Repairing the damaged area so ...
3
votes
2answers
40 views

What does pain look like in wave form?

I am interested in understanding what "pain" and "hot/cold" look like, as far as waves signatures (signal processing) go. My general understanding of how pain (nociceptive pathways) and hot/cold ...
2
votes
0answers
15 views

Names of nerves in hands, shins and face

I am looking for the names of the nerves in 3 specific locations of the human body: The nerve running along the "top" (opposite side of the palm) portion of the thumb, from knuckle to fingernail ...
3
votes
0answers
26 views

Single long axon vs serial neurons

Based on the comments in this post and also this chat. For discussions and speculations please comment in the chat. The basic question is what is the advantage of having a single long axon such as ...
0
votes
0answers
6 views

What is the biggest facultative anaerobic metazoan known to science?

Related: What's the biggest obligate anaerobic organism discovered till now? I had always assumed that the Riftia tube worms were obligately anaerobic since they lived next to anoxic volcanic ...
0
votes
1answer
16 views

Are transgenders born physically different from others?

Are all children born with only either male or female body parts (other than exceptions), or is there actually a natural third gender with the physical characteristics of both genders, e.g. the child ...
4
votes
1answer
150 views

What's the difference between Ki and IC50?

I have just read this post at researchgate: "How to calculate experimental binding free energy from the IC50 value" I am not be very sure about what the difference is between Ki and IC50. Could ...
0
votes
0answers
9 views

Spinolactone's role with adrenergic agents in heart failure?

I am studying the treatment plan of adrenergic agents for heart failure. Then, in the group discussion, spinalactone was included. But I cannot understand how it is relevant when considering ...
4
votes
1answer
31 views

What's the biggest obligate anaerobic organism discovered till now?

Beside many anaerobic single cell organisms, there are some annelid worms that are obligate anaerobic at least in their early development stages. Probably, due to low concentration levels in nature, ...
4
votes
2answers
28 views

Regarding cellular self-destruction

I heard and read telomere 'health' or 'length' ( if that's right ) has alot to do with cell 'health'. If telomere 'abilities' are 'restored' to a 'healthier' status then the cell it is in functions as ...
2
votes
0answers
15 views

Why are irises unique?

I heard that irises are different and unique for every person. That's how iris scanners identify the identity of people. This technology is becoming very evident. So I ask, why are irises for each ...
0
votes
1answer
10 views

Binding of Multivalent Antibody to mutiple epitopes?

A multivalent antibody molecule such as Immunoglobulin M Immunoglobulin A etc bind to more than one antigens or epitopes but I am confused about that wheather these multivalent antibodies bind to ...
4
votes
1answer
212 views

Software for counting fly eggs

Is there any software that could be used to rapidly (quicker than humans) count the eggs laid by Drosophila on a substrate by placing them under a microscope with a camera attached? The eggs are laid ...
7
votes
3answers
106 views

Can a single axon propagate multiple simultaneous action potentials?

I have not been able to locate any research that indicates whether a single axon of a neuron or nerve cell can conduct multiple simultaneous (i.e. spatially separate) action potentials. I am aware ...
2
votes
0answers
39 views

What are the common methods to estimate additive genetic variance?

Additive genetic variance can be estimated in a number of ways, and is a key concept in evolutionary biology and quantitative genetics. What are the typical methods (experimental designs) used to ...
3
votes
1answer
92 views

DNA content in seeds vs. fruit flesh

Is there a publication comparing DNA yield and / or PCR-amplifiability after extraction from fruit flesh (like apples, oranges, cherries etc) in comparison to seeds of the same fruits ? I would prefer ...
1
vote
0answers
16 views

How do I get recombinant proteins into the nucleus of mammal cells?

I know that there are Nuclear Localisation Sequencenes (NLS). They can be taken from endogenous or viral proteins and fused to the N or C terminus of my recombinant protein. Which is the best one? ...
12
votes
3answers
886 views

Hot water and bacteria

I know that it is common to say, "use hot water when washing your hands" or when you've got a cut, "wash your hands with warm water," etc. I was wondering, why is this the case? Since bacteria grow in ...
1
vote
0answers
8 views

Regarding tumors and their developement

If certain cells or tissue in a specific part of the body are for some reason overworked; like the cases of severe acid reflux damaging the throat repeatedly and the cells in the throat having to do ...
1
vote
0answers
66 views

Nasal Chronic Inflammation after influenza virus [on hold]

I am studying the nasal secrotory system of the nose (lymphatic system not relevant; serum) after infection of influenza A virus when there is a big red edema at the back of the nose. I found no ...
4
votes
1answer
29 views

Balanced vs Maximized Codon Optimization

I have worked with the optimization of several viral proteins, from different viruses/families, with different results. When Menzella, 2011 was published I tried that method. I found quite the ...
2
votes
2answers
267 views

Can I drink warm/hot tap water? [on hold]

I live in Canada and tap water is drinkable, as a matter of fact, the government puts a little bit of flouride in the tap water so it cleans your teeth. My wife and mom always tells me not to drink ...
9
votes
2answers
179 views

How does an axon “know” it's not connecting to its own neuron?

I recently read about an experiment where they removed the dendrites and axons from rat neurons and placed them on a grid. After a while they started reconnecting and were able to learn things. Since ...
2
votes
1answer
57 views

What is happening physically when I get sleepy and when I wake up?

After a week of too little sleep, I slept about 12 hours last night to "catch up". It made me wonder: what is happening physically that signals that I'm done sleeping, or conversely, that I need to ...
0
votes
1answer
17 views

Nerves, Neurons, Axons and Dendrites by Example

Here is a simple diagram of a neuron: A few (very closely related) questions: Where are receptors located (for pain, pressure, temperature, etc.): in the axon terminals or the dendrite tree? ...
-1
votes
0answers
11 views

How PER:CRY complexes accumulate in the cytoplasm? [on hold]

Lot of paper on the circadian molecular clock talk to an accumulation of PER:CRY complex in the cytoplasm during the day phase. I do not find why this complex do not move to nucleus in during the day. ...
1
vote
1answer
20 views

How can I purify RNA after gel electrophoresis to remove residual acrylamide?

I sometimes use denaturing gel electrophoresis on a preparative scale to purify RNA produced by in vitro transcription. The major issue with this is that the sample after extraction from the gel still ...
2
votes
1answer
362 views

Why are urban birds still scared of humans?

I understand that animals are naturally scared of humans because we basically slaughtered every living thing we found in our way for millennia. How long does it take for them to genetically 'forget' ...
4
votes
1answer
31 views

How could be the “Eurasian magpie” bird won the “Mirror Test” where Gorillas failed

EURASIAN MAGPIE VS GORILLA VS How could be the "Eurasian magpie" bird won the "Mirror Test" where Gorillas failed ? In 1982, mirror tests on two, zoo-reared gorillas failed to demonstrate ...
1
vote
2answers
24 views

Why not use non-visual self-recognition to test for consciousness in an organism?

Background A well-known test for consciousness in an organism is to observe its ability to recognise itself in a mirror (see wikipedia article: "Mirror test"). Question Why haven't I come across a ...
5
votes
1answer
27 views

How does anadromous fish physiology “know” to switch from salt to freshwater and back?

What mechanism allows anadromous fish (like salmon) to switch from salt to fresh water and back? How does the fish "know" to switch its physiology and do other fish possess the biochemical machinery ...
7
votes
1answer
58 views

How to validate the regulatory interactions inferred from gene expression data?

My algorithm learns regulatory interaction between genes using Bayesian Network approach from gene expression data. After the algorithm has converged to a network of interacting genes, how to validate ...
1
vote
0answers
19 views

Physiologically, how can stress/anxiety cause neuropathy?

According to the Mayo Clinic, stress/anxiety can cause "pins and needles" (neuropathy) sensations all over the body. But how can this be? My understanding of the sensory pathway is that sensory ...
-1
votes
1answer
19 views

What is the evolutionary purpose of white spots in nails and how can they be characterised due to Leukonychia? [on hold]

Suppose you haven't hit your nails so the white spots are due to Leukonychia. Are the discoloration i.e. the white spots due to lower porosity (less minerals absorbing) or some other factor? I ...
2
votes
1answer
19 views

Is it possible to dock multiple ligands with the target?

Is it possible to dock multiple ligands with a target? If so, what is the suitable software used for? -- Is it possible to fix specific docking region for the target (or) automatic?
2
votes
1answer
22 views

Why do some animals try to imitate other animals?

There is a tendency of some animals (including people!) to be "copy-cats" and try to imitate members of their own, and sometimes other, species. The most obvious example is a parrot copying human ...
5
votes
1answer
552 views

What is the definition of a stringent/relaxed plasmid?

I have found a publication which proposes some definitions, including a definition for strict and relaxed replication. The definitions are: Relaxed control of plasmid replication. Relaxed control ...
5
votes
2answers
889 views

Do snakes get dizzy?

I've seen snakes get twirled around in bags and was just curious if they get dizzy. I have not done any tests because snakes scare me.
0
votes
1answer
29 views

Satisfication with irrelevant things [on hold]

I am not sure if this question is better suited CogSci.SE so please tell me. My question is why are we satisfied when we get things that aren't useful in any important way? For example, relating to ...
1
vote
1answer
33 views

Can signals travel “backwards” in the sensory pathway?

My understanding of the "sensory pathway" is that its a linear, directional pipeline as follows: Nerves (fire various signals depending on the type of sensors they are) Fibers (transmit signals from ...
7
votes
1answer
495 views

X chromosome “weight”?

According to Wikipedia, the X chromosome has approximately 153 million base pairs, while the Y chromosome has only 60 million base pairs. Thus, the difference is roughly 93 million base pairs. My ...
2
votes
1answer
15 views

Do distinctions between dry, tickly and chesty coughs have any medical basis?

Background At least in Britain you normally come across distinct kinds of cough medicine "chesty", "dry" and "tickly". Questions Are "chesty", "dry" and "tickly" coughs always due to ...
7
votes
4answers
295 views

Is there an 'anti-virus'?

A virus spreads around and usually attaches itself to the host, multiplies & causes diseases. But is there something like an anti-virus? A single celled entity that does the opposite: spreads ...
3
votes
1answer
31 views

Fab fragments of antibodies to fight viral infections

I was reading about Fab fragment and about using them to fight of viral infections. It seems that the Fab attaches to the viral receptors, which stops the viruses from attacking the cells. It seems ...
7
votes
2answers
110 views

Use cases of RNA secondary structure prediction

I'm an undergraduate currently writing a thesis on RNA secondary structure prediction, specifically building upon analysis done by the RNAStructure and Unafold software packages by modifying certain ...
1
vote
1answer
11 views

Persistency of biotoxins in environment

I wonder how long it takes for biotoxins to break down when released to environment, I think about - Botulinum toxin, Anthrax toxin etc. I guess process of degradation should be fast, because high ...
0
votes
1answer
13 views

Cells scatter light in solution. Do they refract?

For part of an exam question, "why do cells grown in liquid cause turbidity?" I answered that cells refract light. The correct answer was that cells scatter light. Isn't the light scattering ...
3
votes
1answer
28 views

Western blotting with multiple antibodies

Normally I wash/detect with one primary/secondary-HRP antibody pair, strip, then wash/detect with the other primary/secondary-HRP pair which works well. However, I recently started working with a ...
-2
votes
0answers
20 views

what makes different materials to have different tastes? [on hold]

what makes different materials to have different tastes? For example: what we know as different colors is due to different frequencies of light and what we know as sound is due to the different ...
1
vote
0answers
22 views

Anatomy of nervous system's sensory pathways

When I touch my hand on a hot stove, I feel pain. I'm interested in knowing all the main "endpoints" (components/parts of the body) that are involved in relaying this pain signal. As I understand it ...

15 30 50 per page