0
votes
0answers
1 views

Relation between double helix CGTA and dominant / recessive genes

How could I understand the relation BB ~ 25%, Bb ~ 50%, bb ~ 25% of being bald versus CGTA? What has one thing to do with the other?
1
vote
2answers
16 views

What is the basic structure of the nuclear lamina

What gives the nucleus its shape is a mesh of intermediate filaments called the nuclear lamina. It forms an interface between the chromosomes and the inside of the nuclear envelope. If these ...
0
votes
1answer
7 views

Primer design for HLA locus

i have designed primers for HLA locus DPA1(exon 2 region) based on Real-Time PCR (qPCR) Primer Design guidelines. primer will start from intron regions to cover full exonic region. ...
44
votes
5answers
3k views

Life without DNA?

I'm by no means an expert in the field, merely a curious visitor, but I've been thinking about this and Google isn't of much help. Do we know of any lifeforms that don't have the conventional ...
-1
votes
0answers
15 views

What proteins can synthesize vitamins?

I am currently doing a research project on vitamin enhanced crops. It says that in DNA tampering, the only thing you can add to an organism is protein. So I am now looking for a vitamin/nutritious ...
1
vote
1answer
15 views

How would i describe a Cladogram as paragraph?

I have this paragraph that i have halfway finished, but i do not know what to put in the spaces. A Cladogram is a branching diagram that represents the proposed phylogeny or evolution of a species ...
4
votes
1answer
161 views

Why AZT is selective towards HIV and doesn't impair human DNA replication?

I've found this article, which is a very old one (from the time when nucleoside analogs where researched as a possible way to prevent replication of virus genetic material, before the HIV epidemics). ...
0
votes
1answer
43 views

if the load is removed from an eccentrically contracting muscle, will it start contracting concentrically?

Geometrically speaking, a muscle contraction should exert a force between the two attachment sites. However, the actual effect of the force on the overall geometry of the body near the point of ...
-1
votes
0answers
15 views

Does mitosis only create somatic cells? Doesn't it also create germ cells? [on hold]

If mitosis doesn't create germ cells, then where do the germ cells that undergo meiosis come from?
3
votes
0answers
25 views

How we share pain?

When somebody else tells me about his or her itching or pain in some specific body part I sometimes begin to feel similar feelings. I can think of about three explanations: I feel pain all over my ...
1
vote
1answer
34 views

Why sigmoid curves appear in quantitative analysis of many biological phenomena? [on hold]

I know two examples: 1-The binding of hemoglobin to oxygen (binding of oxygen to one site of hemoglobin induces conformational changes which increase the affinity of the other sites for oxygen - the ...
3
votes
1answer
25 views

Do cell membranes have more phospholipids in one layer than in the other?

Assuming the cell membrane to have a spherical shape, geometry tells us that the area of the inner leaflet is smaller than the area of the outer due to the difference in radius between them. Does this ...
0
votes
0answers
14 views

Show the relationship between genes when we have a proof crossing and types are given [on hold]

At the tomato A- round fruit, a- long fruit, B- smooth fruit, b- creasy fruit. In a proof crossing we have these types: 24 individuals Ab, 266 AB, 246 aB, 24 ab. Show the relationship between genes. ...
3
votes
4answers
32 views

Enzymatic error rate

I am aware that each enzyme generate a certain amount of misproducts. This is well documented, for example, for the DNA polymerase. I am interested in enzyme involved in biochemical processes, so for ...
2
votes
1answer
8 views

Are the proteolytic enzymes in syconiums and nettles identical to those in rennet?

I would like to compare rennet capability under various conditions. The issue is, I don't want to use calf rennet, but I can't figure out if nettle and syconium, which also coagulate milk, contain ...
0
votes
0answers
10 views

Standard solution for alkaloid separation in HPLC [on hold]

In the middle of my college project, I am in need of performing alkaloids separation from Aloe-vera using HPLC. Can anyone help me by mentioning the standard solution to be used for this separation?
1
vote
4answers
47 views

Why are there both stop and start codons?

Based on my understanding from wikipedia, there is the (RNA) start codon AUG and the stop codons UAA, UGA, UAG. AUG can also encode Methionine, I'm assuming if it appears in the middle of a mRNA ...
0
votes
1answer
56 views

How to select genes before log2 ratio on a RNASeq gene expression matrix, based on signal median

I want to transform a TCGA mRNA expression matrix (in linear data format) to log2-ratios and then run a feature (gene) selection, selecting the 1000 most variant genes (genes with higher standard ...
1
vote
1answer
13 views

Repair of cloning vector nicks digested with antarctic phosphatase and ligated with T4 enzyme

The vector product obtained by ligation between a vector previously digested with antarctic phosphatase lacks 5' phosphate groups. T4 ligase can ligate it to an insert with complementary sticky ends ...
-2
votes
0answers
23 views

I am a biology student and m confused about my future after intermediate now m seeking a profession beyond medical line [on hold]

I want to know all the career options associated with biologystudent except medical professions ......Plz provide the best options...... Scope Benefits Demand Earning
-3
votes
1answer
40 views

Why do humans need a heart? [on hold]

When I looked up the function of the heart, it says the heart pumps blood throughout the body. But the blood is already throughout the body, as it is recycled back to the heart. It is a chick-egg ...
0
votes
1answer
15 views

Two heterozygote mice for skin color are reproduced. Find the probability that in 3 children 2 will be dark and one white

Two heterozygote mice for skin color are reproduced. Black is dominant to white color. Find the probability that in 3 children 2 will be dark and one white. How did you do the ordering. Well I found ...
2
votes
1answer
42 views

Is it possible that a set of functionally related proteins in a pathway fulfill different functions?

Could it be that a given pathway of enzymes (or proteins in general) may fulfill different purposes in a cell by for shifting partners? Say protein A activates B, B activates C and C has a specific ...
7
votes
1answer
226 views

Are bacteria necessary for an individual's life, or, how long could a person live without bacteria? [on hold]

Bacteria are essential to life in that they are responsible for breakdown of organic substances, etc. but are bacteria necessary for an individual's life? In other words, how long would a human ...
2
votes
0answers
31 views

How can TMS induce enough depolarization to cause an action potential?

Creating an action potential needs at least tens of mV potential difference across the membrane to occur. But the membrane is really thin, surely less then 0.01µm (some reference give 25A). Then the ...
3
votes
1answer
19 views

To which negatively charged components of the cell envelopes do the crystal violet complexes bind in gram staining?

The gram positive have negative components in the peptidoglycan layer in the form of teichoic acid phosphodiester bonds, and the gram negative have negative components in their outer membrane in the ...
0
votes
1answer
21 views

interpreting enhancer and promoter regions of a target gene

I am reading a paper which talks about promoter/enhancer regions of certain protein coding genes. These genes are for which evidence points to having strong MEF2 transcription factor binding sites. ...
2
votes
1answer
30 views

Detailed mechanism of the cause of diabetes mellitus type 1?

I have read in some texts that diabetes mellitus type 1 is caused by degeneration of beta cells due to our body's own immune reaction.Is it true? Can you explain further how are such types of immune ...
2
votes
0answers
22 views

Normal ECG/EKG Measurement?

I'm getting started using ECG using a 3 lead system by iWorx. I have place the leads on my two wrists and the ground on my ankle and have recorded some data into the provided LabScribe 3 software ...
1
vote
1answer
39 views

Why is heart failure treated as more critical than kidney failure?

The heart pumps the blood to supply tissues and kidney always filters the blood to remove urea,extra water and etc. And all these are vital,so the kidney is as important as heart: and my question is: ...
0
votes
0answers
10 views

is Acinetobacter spp produce biofilm [on hold]

Is Acinetobacter spp. produce biofilm ? And what the basic properties of this bacteria like biochemical test?And some literature about Acinetobacter.
1
vote
1answer
28 views

How do genetic chimeras with different blood types not die?

If a person is a chimera and has two different blood types in his veins, how does he not die? Shouldn't the immune system attack one of the blood types? In 1953 a human chimera was reported in the ...
13
votes
3answers
673 views

Are there cats with black skin?

Some mammals can have a black, pink or spotted skin, depending on race - see for example humans or pigs. But I recently learned that this is not the case with mice. Even black furred mice have pink ...
1
vote
0answers
24 views

how food moves in horizontal coils of small intestines [duplicate]

This is a very very basic question, and I am looking at it more from point of view of physics. The small intestine is a highly coiled structure, which means it has horizontal coils as well. I can ...
1
vote
1answer
66 views

Crossing white eyed Drosophila with sepia eye

So, I'm doing some drosophila experiments with my high schoolers and I had really poor production of wild type individuals for doing the experiment resulting in not enough to cross with everyone... I ...
3
votes
1answer
49 views

Survival of streptococcus after my scarlet fever

I'm currently sick because of scarlet fever but I got treated with antibiotics. I know that after 1.5 day using antibiotics the streptococci I release at home are dangerous anymore. But my question ...
1
vote
0answers
8 views

Plants and animals ability to survive polypoidy conditions [duplicate]

In mammals the condition polyploidy produce something euphemistically termed "general developmental disruption" ,practically speaking this means system meltdown which happens very quickly. There is ...
2
votes
0answers
18 views

Protein-Bound Drugs in Kwashiorkor

Kwashiorkor is characterised by decreased serum protein (including serum albumin) due to poor dietary protein intake. What is the effect of this lowered serum protein on highly-protein-bound drugs? ...
5
votes
2answers
1k views

Are Asians more genetically homogenous than other races?

I've heard that Asians (I'm not entirely sure which subgroup was being referred to) tend to be more genetically homogenous than other races, with people of African lineage being on the other end of ...
4
votes
1answer
43 views

What (open) software there are for simulating behaviour of human (cortical) neurons?

Is there any reliable open-source software for simulating the behaviour of human cortical neurons? I am looking for serious software, so let's assume I have access to a computer with more than 10,000 ...
2
votes
2answers
24 views

Biochemical coupling between two enzymatic reactions - Enzymes physically associated?

I am wondering what the exact definition of biochemical coupling between two enzymatic reactions is. I know that these two enzymatic reactions have to share the same intermediate(s) one is ...
1
vote
1answer
51 views

How are 23 chromosomes in human sperm chosen?

I'm not biologist and I have just a basic knowledge. I've been thinking for a long time about the following question: How does the body choose which 23 chromosomes should be active in human sperm and ...
3
votes
2answers
134 views

Are these cats calico?

Calico cats are cats that have 3 fur colors and are always female or males two X chromosomes. I've seen many cats that will have 2 fur colors (one of them is usually white) and another, third, color ...
-1
votes
0answers
20 views

Variables of an Experiment? [on hold]

So the experiment that i did was using a dialysis tubing as a model cell to test the process of osmosis. The IV is the amount of sucrose concentration put into the dialysis tubing. The tubing is then ...
0
votes
0answers
13 views

What are the forms of host pathogen interaction [on hold]

What are the forms of host pathogen interaction apart from the host pathogen protein protein interaction?? Or is protein protein interface is the only one way of host pathogen interaction?? I am ...
1
vote
1answer
365 views

Complementarity Determining Regions (CDR)

Complementarity determining regions (CDRs) are part of the variable chains in immunoglobulins (antibodies) and T cell receptors, generated by B-cells and T-cells respectively, where these molecules ...
5
votes
1answer
57 views

Why does high pH result in the denaturation of DNA?

In the Southern blot method, for example, a solution of NaOH is used to denature the DNA in the sample. I find this counterintuitive since I expected that $\text{Na}^+$ cations would neutralize the ...
0
votes
0answers
54 views

Can DNA & RNA be considered as nature's programming language?

The final frontier of Biological Sciences could be considered understanding the effects of variation in the DNA (and RNA). If after fertilization the DNA of the zygote could be genetically ...
0
votes
0answers
15 views

Multivariate Generalized Linear Mixed Model [on hold]

I'm trying to run a multivariate generalized linear mixed model on a data set. I have 4 response variables, 3 fixed factors, a covariate and a random factor. SPSS can't do the analysis. I've tried ...
2
votes
0answers
31 views

What's the (or some of the) minimum(s) amount of atmospheric carbon dioxide needed by plants?

We currently have a problem of increasing CO2 in the atmosphere. But assuming we find a way to carbon sink it, what is the minimum CO2 we need to leave in the atmosphere to provide a source for ...

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