2
votes
4answers
114 views

What exactly is Tinnitus?

What exactly is tinnitus? What is it's cause, and why do some people hear it and others don't?
3
votes
3answers
60 views

Does a reduction in stem cells mean possible earlier death?

The basis of this question relies on my understanding of these 2 facts: ...
1
vote
3answers
409 views

DNA is charged negative. Where is all the positive charge in my body? [on hold]

DNA is charged negative. Where is all the positive charge in my body?
1
vote
1answer
11 views

naturally occuring fatty acids

The double bonds in naturally occurring fatty acids present in our body are in cis configuration while the enzymes for beta oxidation can act on trans double bond.Then what will be the significance of ...
1
vote
2answers
36 views

Hiding identical sequences in NCBI web interface

Sometimes there are identical sequences in Genbank/Genpept, most often coming from the same species but different strains. Ie if I look up "bacteria chitin synthase", the 624-aa protein from Dickeya ...
-1
votes
1answer
40 views

What organism most efficiently coverts a given quantity of mass into heat? [on hold]

Question I am trying to answer: In the popular film The Matrix, heat given off by humans is harvested as an energy source. I wondered, if this were possible, would humans be a good organism to ...
3
votes
1answer
16 views

Is there a realistic “family tree” model for the human population?

I would like to do some gene inheritance simulations, and I was wondering if there is an accepted model for what mating looks like in the general human population? I am not necessarily looking for the ...
2
votes
0answers
6 views

Books for biology,popular but rigorous?

There are very goods in physics and mathematics (like Feynman lectures for exemple) that give an elementry but but broad view of their,therefore I'd like for help to find help to find a biology book ...
8
votes
3answers
146 views

Book recommendation on population/evolutionary genetics?

I have recently been involved in collaborations that require me to model the population genetics of eukaryotic populations. I fear I may either be "re-inventing the wheel" or making conceptual ...
2
votes
2answers
35 views

Conservation Genetics - Book recommendations

Can you please give me some advice for a book in (evolutionary) conservation genetics that offers an in-depth review of the mathematical formulations used in this field. I read the book Evolutionary ...
1
vote
0answers
10 views

How to measure trajectory regularity?

I have two animal running trajectories. A regular one with repeated back and forth running between point A and B, like the one on top in the figure. The other one is very irregular, animal paused and ...
3
votes
1answer
40 views

Mammal body density

Human body density is approximately 1 kg/l (same as fresh water) - which is not surprising (at first) given that we are 70% water, and is surprising (on a second thought), given that the other 30% can ...
4
votes
1answer
36 views

Why does the sacrum fuse together?

Everywhere I look describes how the 5 sacral vertebrae start fusing together during adolescence and are totally fused by the time you're 30 or so. But nobody seems to explain why this happens. It ...
9
votes
2answers
60 views

Is it possible to combine live attenuated and non-live vaccines?

There are many combination vaccines available but I've noticed that there don't seem to be any with both live and non-live components, e.g. DTaP/IPV/MMR. Such combinations could be useful in some ...
3
votes
1answer
45 views

how can a pseudo coelomate like ascaris lay 200k eggs in a single day

as per this site the dimensions of eggs of ascaris lumbricoides are 78-105 microns and as it is shown in the pic down here only half of the body cavity would be used for storage of all the stages of ...
0
votes
0answers
5 views

Based on which criteria should i choose the calibrator sample to calculate delta_delta_Ct

I want to calculate the gene expression of an experiment with the Delta delta Ct method. Two files with results of a real time PCR has given to me. The first one has the results with primers for ...
0
votes
2answers
37 views

Questions about the Evolution Theory [on hold]

I'm trying to understand more about evolution theory. (I am coming from a mathematical background) What i understand till now is that the "improvement" of the dna is a purely random development and ...
4
votes
0answers
21 views

How do I read a sequence logo?

I'm looking at a paper that uses several sequence logos to illustrate the consensus sequence of certain sites. Here is the most important of the sequence logos I'm interested in: The explanations ...
1
vote
0answers
13 views

What makes certain obligate anaerobes viable in fermentation starter cultures?

If Propionibacterium are obligate anaerobes (to wit, poisoned by oxygen), what makes 'Dairy' or classical propionibacteria (e.g. P. shermanii, P. jensenii, P. acidicpropionici, et al) viable in ...
8
votes
1answer
256 views

What kind of skull is this?

We found this skull on a beach in southwestern Sweden, and are curious as to what kind of animal it was.
4
votes
4answers
168 views

What kind of microscope for ML/biological research?

I am a computer science student, focusing on machine learning applications. I have been always interested in biology but I lack any training in it. Now, I had an idea that I could introduce myself to ...
5
votes
2answers
290 views

What exactly does adaptive mean?

This is a quote from Dey et al 2014: Hatching asynchrony is thought to be adaptive because... What exactly does adaptive mean here? Does it mean hatching asynchrony has fitness benefits? Or does ...
4
votes
1answer
131 views

What makes a DNA sequence motif a DNA sequence motif?

I've read about DNA sequence motifs, but still don't understand what makes some sequence a DNA sequence motif. Is this a well-defined concept? For, example, What are DNA sequence motifs? says: ...
5
votes
1answer
50 views

No digested product bands, but markers are visible. What could be the reasons?

I had to digest my insert containing plasmid and another vector into which my insert has to be ligated, each with BamHI and NotI. Upon digestion, I ran the gel to check for results. The digestion ...
4
votes
2answers
179 views

Why is assembling paired end illumina without any input parameters an important problem?

In one of the comments in this question about multiple sequence alignment, it was stated @5heikki: btw if you want a good bioinformatics problem, come up with an assembler that assembles any ...
3
votes
1answer
189 views

Why do carrots spoil so fast?

The carrots we buy from a supermarkets spoil very fast, albeit giving many consumers a false sense of preservability due to their structural rigidity. The answer extends to many other vegetables many ...
4
votes
1answer
126 views

Will a completely removed cat whisker grow back?

I just accidentally pulled out, while playing, my cat's whisker entirely, follicle and all. I feel terribly as I know she is a kitten and whiskers are rooted deep in a place rich in nerves. I'm ...
1
vote
1answer
29 views

Anaphase Microtubule Disassembly

Centromeres move toward the poles as the microtubules that connect them shorten. This shortening is due to the removal of tubulin subunits from the kinetochore ends of the microtubules. I'm confused ...
1
vote
2answers
36 views

Recommended sequence clustering algorithm for transcriptome data

I'm working on a project where I'm going to analyze a large amount of transcriptome data. After assembling our RNA-Seq reads into contigs using Trinity, it looks like I'm going to have about 10GB of ...
3
votes
1answer
26 views

Verifying Protein Folds

I have recently begun using Folding@Home and I am curious how people are prevented from cheating the system. It seems to me that unless the final result is easily verifiable users could submit bogus ...
2
votes
2answers
57 views
+50

What is the difference between drought resistant non-succulent plants and plants that cannot be allowed to dry out?

What features make one plant able to withstand dry spells better than another with relatively similar structure? For instance, one of my Rudbeckias is wilting from drought at the moment, and an ...
5
votes
1answer
60 views

Excretion of monovalent and divalent ions in sharks

I have heard that sharks excrete $\ce{Na+}$ and $\ce{Cl-}$ by their gill surfaces but divalent ions like magnesium are excreted through feces. What could be the reason behind this?
2
votes
0answers
44 views

How to track and describe the evolution of a gene?

So I have a project student (undergraduate) who has been assigned a project to study the evolution of a gene (and possibly related genes) through species. I am not an evolutionary biologist, and hence ...
4
votes
1answer
112 views

Accurate Human Skull Model for Educational Purpose

I want to buy a model of Human skull for education purpose. However, I really want a very accurate model and at a decent price. I got the info that many of the available skulls in the market are not ...
2
votes
1answer
52 views

Two-fold cost of sex and r/K selection theory

This article cites a bunch of articles (I haven't been through them) that the effect of the two-fold cost of sex is "reduced" in stable environment or in K-selected environment. It says: [..] the ...
3
votes
1answer
36 views

What is the core mechanism behind neuroplasticity?

Specifically I am looking at reopening of the critical period of plasticity. Modern neuroscience has started to unlock the secret of neuroplasticity. A common experimental setup is with mice. They ...
3
votes
1answer
66 views

which signalling pathway is involved in cancer?

Columnar epithelial cells from the colonic mucosa are studied to identify abnormalities in cell signaling pathways. Abnormal epithelial cells from colonic adenocarcinoma are shown to have a mutation ...
4
votes
1answer
79 views
+50

Breakdown of energy expenditure at the level of a single cell

The metabolic rate measures how much energy an organism expends over a unit of time. Its breakdown for the human body in terms of its functions is well documented : so much for the heart, for the ...
2
votes
0answers
59 views

How are new staining protocols designed for microscopy?

How are new staining protocols designed for microscopy? Is it manual work or does it rely on computer simulations? Say for example I thought the H&E staining does not bring enough contrast. How ...
5
votes
2answers
81 views

What's the smallest organism that can produce voice?

What's the smallest organism (animal, insect, or any living creature) that can produce voice. And not just make sound, but has an organ to specifically to create sound, like how us mamals have vocal ...
3
votes
1answer
63 views

What is the state-of-the-art algorithm for multiple sequence alignment?

Which algorithm or algorithms are considered the standard or state-of-the-art for multiple sequence alignment? How big is the need for better algorithms? How many sequences need to be alignment in a ...
5
votes
1answer
48 views

Scale up of Bacterial growth from 250mL to 1-5L?

I am currently growing up a specific strain of E.Coli with a knockout in 40mL of growth medium (LB) in a 250mL shaker flask... My ultimate goal is to scale up this process to a 1-5L large scale setup ...
2
votes
1answer
36 views

Standard datasets for testing new multiple sequence alignment algorithms?

Are there any open and freely distributed standard datasets for testing new algorithms for multiple sequence alignment?
2
votes
1answer
40 views

Is the human collarbone supposed to break?

I've read it in a book and have heard people mention it, but I can't find any documentation about it. But the point being made is this: The human collarbone acts as a shock absorber for impact on ...
9
votes
3answers
618 views

“Same” DNA vs genes [duplicate]

It is often cited that humans share 99% (or 98%) of their DNA with chimpanzees. On the other hand it is stated that siblings share only half of their genes. What (if any) is the difference between ...
1
vote
2answers
50 views

Is there a correlation between total neurons and intelligence?

Thanks for looking. First off, I am not a biologist, just a curious layman, so I apologize in advance if this isn't a "good" question. Please don't downvote me into oblivion. I read today that the ...
3
votes
1answer
42 views

Is there revolution in humans since the first homo sapiens sapiens

In a thinking mood, I was wondering if the human species has changed since they have first become homo sapiens sapiens. I asked myself this question because I was thinking about how we will evolve ...
2
votes
0answers
16 views

What does salt do to styes?

Styes formed in the eyes are cured by dabbing at them with lukewarm water(I saw this being done many a times as a home remedy.) At times, common salt is added to the water before dabbing. My mother ...
-5
votes
0answers
31 views

Wild Boar: Ways they can harm humans [on hold]

How can a wild boar injure, seriously injure or kill a human being, given that the human is conscious/ awake and fully able? That's all, thanks! EDIT: Understanding that a wild boar's weight could ...
8
votes
1answer
64 views

E coli cotransformation efficiency

What is the E coli transformation efficiency for 2 plasmids? Are any studies that have looked at the correlation between number of plasmids transformed and transformation efficiency? Is there a ...

15 30 50 per page