-2
votes
0answers
15 views

high throughput free software to predict blood-brain barrier permeability

I need a desktop app to predict blood-brain barrier (BBB) permeability of a few thousand compounds. I've searched for hours but didn't find a free software for that. All of the apps are either ...
2
votes
3answers
93 views

Swapping genes?

So, gene therapy is to take out a gene, correct its mutation, and put the corrected one back into the organism, right? Is it also possible to take out a gene from an organism and put in a totally ...
5
votes
2answers
2k views

Does the light color spectrum and frequency matter for photosynthesis?

Do plants grow differently when given sun light, wolfram lamp, fluorescent light, LED light, infrared, ultraviolet, x-ray, unfocused laser and stroboscope?
-2
votes
1answer
23 views

Biologically, does life and death matter? [on hold]

(Sorry that I'm on mobile, so I can't make a good formated question (no links). I will add them later. Just can't resist the urge to ask) In the recent hot question about whether mitochondrial is ...
0
votes
1answer
28 views

What is the strand specificity of a reference genome?

It's a simple question but I've come across many people who have this question, is the reference genome Positive of Negative strand? Indeed, I've had heated arguments over the same issue. So here's ...
5
votes
1answer
112 views

Why is leucine amino acid used the most in proteins and tryptophan the least?

The amino acid leucine, is used in proteins more than others. Leucine with 9.1 percent (its average in more than 1.150 different proteins) is used most and tryptophan with 1.4 percent is used less ...
3
votes
1answer
265 views

Help identify this awesome climbing plant with velcro like stem

I got this plant sprouting in my window box this spring. Starting from a single seed, it has grown into an impressive array of branching climbing vines, reaching 6 feet tall. The stem turned red as it ...
2
votes
2answers
3k views

Which hormones can cross the blood brain barrier?

Can hormones such as testosterone, aldosterone and estrogen cross the blood brain barrier? I looked on Wikipedia and there no mention of it in the testosterone article. Through Googling around I also ...
12
votes
1answer
255 views

How do you design a drug to be delivered to the CNS?

I have just started reading up on structure-based methods for drug design (this is completely not my field so apologies for stupid questions that will be coming along!) Clearly, some drugs are ...
0
votes
0answers
14 views

What is a standard academic resource for abiogenesis, i.e. how life arises from non-living materials?

I am trying to understand the current work on abiogenesis in biology, e.g. primordial soup, the Miller-Urey experiment, etc. What are the recommended texts to look at for this subject? Who is ...
5
votes
2answers
37 views

How do animals end up in remote areas?

I was thinking specifically about random marshy water holes on farmers fields. It seems that you can visit just about any one of these and you will find frogs if you look hard enough. They usually ...
1
vote
1answer
17 views

Is household ammonia okay for plants?

My father-in-law claims that since plants need nitrogen to produce proteins, and since ammonia is NH3, that Ammonia should be fine for the plants, since it's just nitrogen and water and hydrogen, ...
-2
votes
1answer
31 views

Stimulate a nerve [on hold]

My question is that can we stimulate a nerve from far distance? Distances about 5 to 6 cm. Or can we send a stimulation to a nerve from a non neuroal tissue? Edit : excuse me but instead of ...
1
vote
3answers
41 views

Merge several .ab1 sequence files into a single FASTA file?

I have several .ab1 files generated from Chromas. I want to merge all of them into a single FASTA sequence file. How can I do this in an automated way? Note that I don't have Chromas installed (the ...
1
vote
1answer
16 views

Gene and Protein isoform

What is the relationship between term "Gene isoform" and "Protein isoform"? Say a gene can make 3 isoforms, will it produce only (maximum) 3 isoform protein?
1
vote
0answers
21 views

Through which mechanisms did the Drosophila Histone Cluster evolve?

The Drosophila Histone Cluster is a gene cluster that contains more than a hundred copies of a sequence that encodes several histone proteins. These copies are very similar. My question is what ...
3
votes
1answer
38 views

What is this butterfly?

The following guys (about an inch long) were seen in the Willamette Valley of Oregon in summer. When one would fly by a resting one, they'd get into a high-speed little "dogfight". What genus might ...
14
votes
4answers
4k views

Are mitochondria dead?

In the video "What is Life? Is Death Real?", the subject of mitochondria is raised at 2:58. At 3:12, the narrator says "[mitochondria] are not alive any more: they are dead." What currents of thought ...
2
votes
2answers
413 views

Histidine - why essential for children?

Why is histidine an essential amino acid for children but not for adults ? What changes in the body occur which lead to the formation of histidine in adults but not in children ? What causes these ...
1
vote
1answer
57 views

Genetic Diversity in Mitochondria

As I was studying for my GRE exam, I was reading on Mitochondria. I then remembered that they undergo replication similar to bacteria. So I googled for info and found on Wikipedia that there is a " ...
4
votes
1answer
113 views

Lack of A/B-antigen equivalent to Rhesus disease

Rhesus disease occurs when an Rh- mother is exposed to Rh antigens (often due to blood contact with an Rh+ child during delivery) and mounts an immune response which eventually results in the ...
2
votes
1answer
41 views

When did mouth pipetting stop becoming a way to handle liquids in a lab?

Almost all modern lab protocols have an addendum prohibiting pipetting by mouth, instead mandating that a Gilson pipette, a rubber pipette ball, or a serological Pipet-Aid be used. However, it was ...
-2
votes
0answers
14 views

Information about inactivation of restriction enzyme [on hold]

How can you be sure that a restriction enzyme has been inactivated? I tested restriction enzymes on a vector to see whether they were working or whether they were inactivated but I need a simpler ...
2
votes
0answers
21 views

Evolution of protein and protein efficiency

Suppose we have a bacterial protein that performs a function and let's say we can measure the efficiency of the protein. Let's say we have two species, species A and B, both of which have this ...
1
vote
0answers
12 views

Photosynthetic efficiency and light harvesting efficiency

Is there some sort of measure of the light harvesting efficiency (possibly like transfer time) that is directly related to the photosynthetic efficiency in some sort of equation? Also, how important ...
3
votes
1answer
24 views

What would be the impact of depositing limestone in the oceans (to reverse acidification) on ocean life forms and biodiversity?

This question asked: What is the evidence it is feasible to reverse ocean acidification by adding large quantities of a base (bicarb soda)? The result was: Danny Harvey of the University of ...
2
votes
1answer
11 views

dAT joining: please define

I came across a reference to dAT joining in my reading of Genentech by Sally Hughes. The technique is described in passing as a technique for joining DNA fragments used around the late sixties to ...
5
votes
1answer
92 views

Mites on ginger root

I was just looking at some mouldy ginger found in the fridge under the microscope and was horrified/delighted to find (what looked to be) mites growing in it. I have searched the web and can only find ...
1
vote
2answers
24 views

Protein that exit from the cell - as marker

Searching for some protein, that I could use as extracellular marker for mammalian cells. I need to insert mRNA to cell, and to detect the protein outside the cell (not on membrane) if the mRNA ...
-1
votes
0answers
17 views

Why do human genes banks exist? [on hold]

What are we collecting human genes for? Do we need them for preservation?
1
vote
1answer
16 views

What leads to the different types of navels?

Obviously, there are "innies" and "outies" in the human belly button world. Both are the result of a knot tied in the umbilical cord just after birth. But why do some belly buttons become outies ...
8
votes
3answers
13k views

Why do toenails grow much slower than fingernails?

As the title suggests, I've noticed that my fingernail grow much faster than my toenails. For instance, I usually trim my fingernails every two week or so, but for toenails the number would be about 6 ...
3
votes
1answer
36 views

What is the name of this flower?

A flower has grown on a leaf in our garden. What is the name of this flower? Give some description.
2
votes
0answers
24 views

Can HIV mutate to become airborne?

HIV has a very high mutation rate due to its inability to correct errors in DNA replication and it is very adaptable to its environment. Hence I wonder whether is it possible for it to mutate such ...
3
votes
0answers
48 views

Why are lions the only social cats?

We know that almost all cats are solitary. How did the Lions end up social animals? Do we have an explanatory evolutionary path describing how the Lions became social while the rest of the felines ...
0
votes
1answer
35 views

What organisms challenge the concept that all life today descended from a common ancestor?

If I understand correctly, the concept of the LUCA (last universal common ancestor) is based on the hypothesis that archaea and bacteria share common ancestry. In the realm of mathematics, the same ...
2
votes
1answer
67 views

Will a 0.2g/mL sugar concentration cause vomiting in humans?

This infographic claims that the sugar content in a can of Coca Cola would cause vomiting if not for the phosphoric acid. In The First 10 minutes: 10 teaspoons of sugar hit your system. ...
-2
votes
0answers
26 views

how does the body know it has damage [on hold]

Basically what i am asking is what are the steps that the body takes to monitor its own self for damage ? the mechanics of this monitoring. Some starting points or short resume would be greatly ...
2
votes
0answers
13 views

What is the top speed of muscle contraction?

Currently I am looking into what muscles groups are most used during a football kick. I have a hypothesis that the quadriceps are not as used as most people think because the momentum the swing ...
1
vote
1answer
18 views

Ancestral Allele and Hapmap

I notice on dbSNP rs6352 has an ancestral allele of G - http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs=rs6352 The hapmap in humans for this allele is very rare, the homozygous version practically not ...
3
votes
1answer
38 views

Is MHC1 knockout sufficient to prevent transplant rejection?

A few days ago I read about MHC1 knockout pigs for organ transplantation research. I was just wondering, is it enough to knock out MHC1 in the donor (lets say from same species, pig to pig) for ...
3
votes
1answer
183 views

Have webs woven by LSD-intoxicated spiders ever been studied for their efficiency in fly catching?

I ask, because I have a different interpretation of the experiments performed on web-weaving spiders. The famous Robert Pirsig maintains that LSD is somehow helpful to web-weaving spiders, because it ...
-1
votes
0answers
17 views

Do i have Nocturnal lagophthalmos [on hold]

I am a 13 year old girl with a regular everyday life.But lately my mom has been repeatly telling me i sleep with my eyes open and rolling in the back of my head.It has been happening every since i was ...
3
votes
0answers
20 views

Why do crabs spit?

Last year I photographed this juvenile Sally Lightfoot Crab (Grapsus grapsus) 'spitting' (click for larger view): I thought I'd look up more information on this behavior, but couldn't find any ...
12
votes
1answer
6k views

Why does scar tissue change color?

I was wondering why, when you are cold, scar tissue turns bluish or purple while original skin stays the same color. The only thing I can think of, is that maybe scar tissue gets less circulation ...
-6
votes
0answers
22 views

What is this caterpillar? [on hold]

Found in Colorado but may be from out of the U.S. Can we save it? What kind is it? I can send a picture of it if you email me back.
1
vote
1answer
30 views

Possible calculations with temperature, humidity, images and VIS spectrum of a plant in an Integrating sphere

I am currently working on a project which involves growing some plants in a integrating sphere made of foam. I have added temperature, humidity and soil moisture sensors as well as a Spectrometer (350 ...
6
votes
1answer
57 views

Flower identification: Moscow, Russia

I found this plant near the MSU, Moscow, Russia. Could someone help me to identify it?
0
votes
0answers
11 views

translation rate regulated by transcription factors?

I'd like to know if there is in the litterature some examples of transcription factors capable to impact not just transcription but also translation rate so that both can be adjusted. I would be very ...
6
votes
1answer
64 views

Butterfly identification: Dorset England, July.

Can you please identify this butterfly. It was seen in Dorset England 9th July. I think it is a female Silver Studded Blue.

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