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It is definitely possible to include antibodies and other biological molecules in formula to better approximate that of its mother's milk. However, there's no way you could mass-produce this. Every mother has unique antibodies, even horomones that are the same in different people are present at different concentrations. The current "formula" on the market ...


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There are three pathways by which soluble antibodies (which is what the Fab fragments arise from) can inactivate viruses (from Janeway's Immunobiology): What you describe with the Fab binding to the viral receptors is a type of neutralization. Janeway claims that the type of naturally occurring antibody primarily responsibly for neutralization, IgA, is ...


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What you can do depends on your proteins: If both proteins (your target protein and the loading control) are seperated far enough, you can detect both of them in the same step by adding both primary antibodies and both secondary ABs into the buffer at the same time. They will bind only to their specific epitope and you will get nice signals. This is ...


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Problems: Where are the anti-antibodies created? In a mouse or in a human? Well, of course, you can't use humans to create antibodies so we are left with mice. So what's wrong with that? Anti-antibodies will be created to the Fc (the constant section of the antibody) region of the antibody because the antibody is foreign and is treated as a foreign ...


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If you are referring to reducing the titer in the immunized animal, you could give the animal a drug that has immunosuppressive properties. Velcade (PS-341) is a drug that effectively reduces plasma cell counts. There are many immunosuppressive drugs available. If you want to reduce the antibodies affinity, you are undertaking a much more delicate process. ...


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As mentioned in the comment, all antibodies have constant regions and variable regions. The variable regions are the binding sites on the ends of the two arms, and the constant regions are the rest of the molecule. When humans are injected with murine antibodies, the immune system recognises and sets up an immune response to them, through generation of HAMA. ...


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It's common for the human immune system to create antibodies against many proteins, even some human proteins. Hemophiliacs who receive regular doses of clotting factor proteins often develop neutralizing antibodies against the clotting factor proteins, even though they are a human protein1. Therefore it's not surprising that antibodies would be developed ...



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