Bioinformatics connects life sciences and quantitative sciences, typically involving the application of software and algorithms to solve computationally intensive questions, such as those in genomics, sequence analysis, and systems biology. Questions tagged Bioinformatics should have a direct biological component; programming questions may belong on Stackoverflow or Superuser.
Bioinformatics is a broad field that interfaces a variety of life science disciplines (biology, genetics, biochemistry, etc.) with a variety of quantitative sciences (mathematics, statistics, computer science, etc.). Bioinformatic techniques typically involve developing and applying software and algorithms to computationally intensive biological questions, such as those common in structural biology, genomics, sequence analysis, and systems biology.
Some scientists draw a distinction between the terms bioinformatics and computational biology. While these areas are indeed broad and diverse, the distinctions in terms is not consistent or well-defined, and some questions from computational biology should include the bioinformatics tag.