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If you are referring to reducing the titer in the immunized animal, you could give the animal a drug that has immunosuppressive properties. Velcade (PS-341) is a drug that effectively reduces plasma cell counts. There are many immunosuppressive drugs available. If you want to reduce the antibodies affinity, you are undertaking a much more delicate process. ...


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Pretreat the enzyme at high temperature before carrying out the assay at the standard temperature – Alan Boyd



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