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This is a very good question. There are specific chemical signals, for instance: 1.) LRR proteins, which help signal neurons to eachother. These are transmembrane proteins which are characterised by their leucine-rich repeat. They serve as some kind of protein labels for other neurons. These proteins are also known in pathogen recognition in our immune ...


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There is ongoing research on this topic, but there is a theory known as inhibition theory. See this from here: Directed attention fatigue occurs when a particular part of the brain’s global inhibitory system is overworked due to the suppression of increasing numbers of stimuli. This temporary condition is not a clinical illness or a personality disorder. ...



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