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The missing science to the question is the failure to realize that water inside a cell is bound to hydrophilic proteins which form an exclusion zone. This EZ is well described in the literature by Pollack. The EZ carries a strong net negative charge and it excludes protons. This has also been confirmed by numerous researchers across the world. The ...


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There's a fairly large misconception here. The huge amount of energy that's available from respiration, and which drives the synthesis of ATP, in fact comes from that reaction that you consider secondary, and that's the transfer of electrons to oxygen. If you want to think of it as two separate reactions, then the first one $$Glucose + 12\ {NAD}^+ + 6 H2O ⇌ ...



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