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Obviously, it is conceivable that DNA could be so damaged that the organism dies. Trivially, blasting cells with radiation will cause rampant DNA damage, which will trigger p53 and lead to the cells suiciding (apoptosis), this is a "deliberate" (so to speak) mechanism to manage cancer risk. In practice, the reason DNA damage leads to death is usually not ...


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It is important for organisms to be renewed. These organisms have less wear and tear, they are modified through evolution to better fit the current environment, they are more likely to have healthy offspring that they can look after. It must also be considered that genetically we must be optimal in anyway that confers our continued survival as a species. So ...


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Perhaps the best type of study to examine the role of genes (DNA) in human aging are twin studies. They have either: the same DNA (monozygotic, one egg, "identical" twins (MZ) ) or similar DNA (dizygotic twins, two eggs (DZ) ) and are perhaps exposed the same, or different environments. I won't repeat the information in the link, above, but studies of ...



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