New answers tagged development
In Drosophila, Toll receptors are used during embryonic development as well as innate immunity. See The Drosophila Toll Signaling Pathway by Valance, et. al. Toll-like Receptors are pattern recognition receptors found in organisms other than Drosophila that recognize common motifs found on pathogens. Toll receptors were first discovered in Drosophila and ...
The short answer is: "Nobody knows yet." The slightly longer answer is that different species use different mechanisms. In amphibians and insect the oocyte, or egg, produced by the mother, has a polarity such that some macromolecules are enriched in different regions of the egg. The best characterized examples are localized RNAs, but there could be other ...
Here's at least one paper describing some of what is known about development of neural network in Caenorhabditis elegans http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1001044 It mentions at least one relevant gene " There is evidence showing that several guidance molecules like Netrin and Nerfin-1 are expressed in the early stages ...
The table at http://genome-mirror.duhs.duke.edu/ENCODE/cellTypes.html lists many commercially available cell lines. The four lung fibroblast lines, including adult and fetal, are listed as endodermal in origin.
All normal fibroblasts are mesenchymal in origin, including lung fibroblasts. In certain situations, usually injury related, epithelial cells can undergo an epithelial to mesenchymal transition (EMT).
The Machinery of Life by David S Goodsell I just picked this up and haven't actually read through it yet, but it looks amazing. Very well illustrated with drawings and molecular models. It's also not overly technical. I don't have much to say in the way of a review, but there's plenty on Amazon. It sort of seems exactly like the book you're looking for.
I recommend Lehninger principles of biochemistry. It is one of the best, most read, and referred books on Biochemistry.
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