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The human genome is composed of roughly 3 billion DNA bases called "nucleotides", typically represented as A, T, C, G. Genes are sequences of nucleotides that encode a protein; but they only comprise about 2% of the full genome. (http://en.wikipedia.org/wiki/Human_genome). Most components of cells are made of proteins. The rest of the genome is made up of ...


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No, your approach will not work, you are taking a very simplistic view of an extremely complex system. Some of the problems you are ignoring are: Genes (eukaryotic genes anyway) are spliced to produce mRNA, a process that removes introns and leaves only the exons. If you just translate the entire chromosome file you will get noise. Splicing also changes ...


7

When people say that siblings share half of their genes, they're talking about alleles, which are different versions of the same gene and generally differ slightly in nucleotide sequence. In essence, all humans share 100% of their genes (almost), but the number of shared alleles varies. Example: geneA, allele1: atgccc geneA, allele2: atgccg geneA, allele3: ...


4

This has nothing to do with the proportion of the genome that is coding as suggested in another answers. The reason the figures are so different is because they are measuring different things. The chimp-human figure is measuring sequence similarity whilst the figure for kin are measuring gene similarity by descent. This gives two sources of difference in ...


3

Entropy is a measure for the number of states accessible to a system. The more states available, the higher the entropy. If you think of an atom confined in a volume V, then, without further restrictions, the atom can be anywhere inside that volume, i.e. the number of states will be a function of the volume V. The bigger the volume, the bigger the entropy. ...


3

Ahh entropy. The bane of many undergraduates. You won't need a lot of mathematical rigor needed to solve for absolute entropies in most biological fields so it's best to think of it abstractly. Consider the atom. What can it do? Well if you remember from chemistry class, it can bounce around a process we call translate, and the electrons can basically ...


2

As this table shows, the more complex a molecule is (in general) the more entropy it has. Entropy is an absolute quantity which is zero at $0^o K.$ When an atom or molecule has no way to rotate (is 'frozen') there is only one state in which it can exist. An atom of a gas or a molecule of a diatomic gas at $25^oC$ is also somewhat constrained compared to a ...


2

Why bother predicting proteins badly from DNA sequence when you could have just as well downloaded the manually curated human proteome? As to your questions: Are you asking about human genomes or genomes in general? The vast majority of the variance in human genomes is in non-coding sequence. As to genomes in general, they vary in pretty much every ...


1

Your problem will finally boil down to searching your sequence in the Blast databases. Performing Blast seems to be probably the best way to find out if your bacteria has that specific protein expressed or not. If you could not find it in the nearest species using Blast, then try running PSI-BLAST, which would return you distant homologs, by which you can ...



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