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Maybe I'm missing something here (and it's not my area of expertise) but... the GHK formula includes the parameter Vm which is the transmembrane potential. This parameter is determined by the intracellular and extracellular concentrations of all ions. A high external concentration of Na+ will therefore influence the net movement of K+. One of the ...


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Most importantly, the whole Goldman-Hodgkin-Katz model is, well, a model. It is a way we would like to find and explain phenomena, given pen and paper. Often, scientists build models in order to explain data in hand, but even then, they will have to add something from their imagination. For example, early astronomers saw planets moving differently from ...



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