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For cAMP there is only one electrophysiological technique I've found. You can use cyclic nucleotide-gated channels in the cell as a secondary indicator of cAMP activity. When cAMP increases in the cell, these channel will fast gate which you should be able to pick up. The issue is standard CNGC's are not overly sensitive to cAMP and are typically more ...


Short answer Any electrophysiological recording of potentials, including the electrocardiogram (ECG or EKG), measures a potential difference. Hence, two or more electrodes are necessary. Background The ECG measures the rhythmic voltages changes generated by the heart muscle. Voltage is defined as a potential difference between two points. Therefore, a ...

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