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A significant amount of heat generated by the cell does not come from the hydrolysis of an NTP. ATP is generated by a H+ gradient in the mitochondria, and this gradient is created by mechanisms which rely only in part by ATP. Most of the energy stores in our bodies are not in the NTP pool. This is why CO2 and urine are used to measure energy expenditure ...


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I was musing on this and did some strange googling, and have some ballpark figures for a bunch of different organisms. It's far from a complete answer but it's at least a start, and all this won't fit in a comment. DNA replication, I assumed, was a huge metabolic drain on the cell. Turns out that is far from the case. Many helicases are passive, requiring ...



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