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First of all you need to clarify what exactly is the output that needs to be regulated. We often say regulation of expression of a gene but what expression ultimately leads to is the activity of the gene (whatever it might be: enzyme based catalysis, cytoskeletal rearrangement, response to an extracellular signal). Activity of course depends on the ...


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I don't understand your system of 3 genes regulatory network question, but I can answer your general question regarding transcription factor self-regulation of transcription/gene expression. Yes, in biology, there are transcription factors that bind to their own gene's promoter-proximal region (on DNA) and regulate their own gene's transcription. There are ...



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