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As I understand, what you really asking is: What is the mathematical model one can use to fit drug lethality/efficiency data? With answer to that you can go to stackexchange and bug them for fitting solution in language of your choice. However, answer to that is quite complicated, it depends on your system and experiment. And also, how well you want to ...


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You can answer this question for yourself using the modMine data warehouse for modENCODE datasets. All you need is a list of female-specific genes (using your identifier of choice, although FlyBase FBGxxxxxxxx are the simplest). You can use their list tools to upload your own list of identifiers, and then there are a bunch of widgets that will tell you ...


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Comparing some commonly used languages in bioinformatics I think that indeed Perl is losing users but there are still quite a lot of people using it. Bash (or other shell) is essential. While one can replace Python with C or Java and eventually replace R by Python or Julia, I find Bash to be really necessary. To compare Python to R, Python is much faster. ...


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I have found that this chapter by Lincoln Stein is a very easy, accessible, and useful introduction to writing a Perl script: Using Perl to facilitate biological analysis. It is Chapter 18 in "Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins" 3rd edition, by Baxevanis and Ouellette. I use Perl and bash for almost everything, but most ...



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