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The term intergenic is more or less obsolete now. In fact it is ironical to say that a gene, which can give rise to a functional protein or an RNA, is expressed from an intergenic region. However the usage continues for both lncRNAs and miRNAs (other major type of ncRNA in metazoans1 - piRNAs have different classification). lncRNAs are vaguely classified as ...


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The Coursera Bioinformatic Methods courses include classes on metagenomics and, more importantly, tools to use when applying these methods. I have not taken this particular course, but Coursera is generally very good with getting hands-on experience using computational tools. A course-like setting may also be conducive to group learning.


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There is no literature report saying such a thing. However, I did a cursory check for GWAS study on neuroblastoma. Selected SNPs with p-value>0.05 Converted p-values to a score — -log10(p-value) Mapped the SNPs to genes while calculating cumulative score for a gene I just sorted the genes based on their names, assuming that many paralogs have similar ...


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Apart from what WYSIWYG said. It might also be the case that you need to re-sequence because you're interested in seeing the changes that might have occurred since the last sequencing. Remember that cells keep dividing and therefore changing, so the DNA is slightly different from one cell to another (and from one population of cells or tissues to another). ...


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Is that correct that a complete DNA sequencing (the whole genome) need only to be done once (per person)? Likely, yes. But I think you vastly overestimate how often this is done. If someone gets their DNA "sequenced" at 23andMe, for example, they are not getting their whole genome sequenced. They are getting individual bits believed to be possibly ...


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As far as I know there are ongoing efforts to find genes that affect forensically relevant traits e.g. facial characteristics and fingerprint pattern type/ridge count, and it's definitely a topic of interest to some law enforcement agencies. However as previously mentioned, there are many factors that could influence complex traits, including in utero ...



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