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I've had a difficult time getting anything definitive to support my answer to your specific question of safety, however, I thought I'd go out on a limb and give you my understanding. A recent review of what is known about this can be found at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809506/ I think you are on the right track with your 'dose-dependence' ...


Rhesus antigen (Rh-D) is inherited in an autosomal dominant pattern. Therefore you are correct in your reasoning. Simple problems like this are often best worked out using Punnet Squares, shown below for the scenarios you have considered. Because the inheritance pattern is dominant, if either parent was homozygous (DD) for Rh-D then 100% of their ...

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