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I think a clear way to rephrase this question would be "How beneficial a mutation needs to be to behave really differently from neutral mutations?". I am answering to this question. Neutral mutations and nearly neutral mutations The probability of fixation of a new neutral mutation is $P_{neutral}=\frac{1}{2N}$, where $N$ is the population size. An ...


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There's two parts to your post that I want to address, the first is the quote (because I want to make sure you understand it well), and the second is about general inference methods for estimating the genetic composition of ancestral populations. The Quote: Selective Sweeps A selected variant that increases rapidly in frequency in the past ~250,000 ...


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There are really two ways to infer past genetics. Sample the past. Only really works if you have well-preserved uncontaminated archaeological samples, but works surprisingly well, considering. The accuracy and completeness goes down fairly quickly as you go back in time but thousands of years to hundreds of thousands of years is roughly possible. You ...



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