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Reference genomes do not accurately represent the set of genes of any single person.it is created by fragments of various donors, which when built,is used as a template for creating the real genome. Though we will find All humans are 99.9 per cent identical and, of that tiny 0.1 per cent difference the reference genome might not be 100% identical to the real ...


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SNPs are much denser than RFLPs and VNTRs therefore the DNA resolution is much greater with SNPs. VNTRs were historically used for linkage mapping while SNPs allowed for association studies (e.g. GWA studies). Therefore your question goes down to what are the differences between linkage mapping and association studies. They are both forward genetic methods ...


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The main reason is because the genetic differences between individuals of the same species are tiny. For the vast majority of studies, they can simply be ignored. Differences between individuals are usually (not always, but mostly) differences in SNP genotypes. These are single nucleotide differences which, while they can have phenotypic effect, don't ...



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