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This is a quite complicated question, as melatonin has quite a range of effects on the cells. First, melatonin binds to three different melatonin receptors, which are found in a wide variety of tissues or organs including brain and retina, cardiovascular system, liver and gallbladder, intestine, kidney, immune cells, adipocytes, prostate and breast ...


From wikipedia article on melatonin receptors (with some modifications) : In mammals, melatonin receptors, which are G protein coupled receptors, are found in the brain and some peripheral organs. However, there is considerable variation in the density and location of MT receptor expression between species. MT1 In humans, The MT1 subtype is ...

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