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Not an experimentalist, so take this with a grain of salt. But for motility you often need some external factor, e.g. a chemokine or chemoattractant (FMLP is a common one for white blood cells). Also some cell types may not crawl on bare glass, and might need a protein or gelatin coating. White blood cells on slides can look like this: ...


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https://www.youtube.com/watch?v=w3o98Ckx9XI Yes, it is possible as seen in this video. They should move on their own.



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