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Is there evidence of selection against long proteins and long genes? I am not aware of any such evidence and cursory googling did not reveal studies that researched a correlation between gene selection and gene size. However, the larger a gene, the larger the probability of a deleterious mutation within said gene so I expect that there is some limit to ...


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Even simpler: If you are lucky and your target Gastropoda is in Ensembl (http://ensemblgenomes.org/) you can just introduce the gene ID and see if it has any paralogs. A lot of other info is available for each gene.


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The simple way to do this is to use blast to search the genomes your interested in for sequences similar to your gene. If there's another copy it'll turn up in the blast results (so will orthologous genes - but they'll have lower scores than an actual copy). That relies on the annotation and genome being correct, of course.



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