New answers tagged molecular-genetics
Just for balance, here is an example of a single protein being constructed from two primary gene products (two separate genes involved) via protein splicing.
The answer is not simple - @shigeta mentioned some mechanisms leading to single gene-to-multi protein relationships - and the answer is certainly not short (there are thousands of these genes). But anyway "alternative splicing" seems to be the primary mechanism according to this article, so rather than listing all alternatively splicing genes, here are the ...
There are a large number of ways a protein variant can be produced by post translational modification. The question may seem obvious, but its really quite broad. I can start this out. I doubt I know all the ways a single transcript can produce variant proteins. A detailed description might be more like a review article than an answer here. First, ...
Echoing what was already mentioned: the DNA sequence directly affects the ability to bind sigma factors (http://en.wikipedia.org/wiki/Sigma_factor). Sequence --> bonding --> how often sigmas bind and for how long they bind --> initiation of transcription
Mitochondria divide by binary fission. The regulation of this division differs between eukaryotes. In many single-celled eukaryotes, their growth and division is linked to the cell cycle.
I agree that it is hard to search for papers but from graduate level classes this is some of the additional insight I have gained. Sequence context of promoters is important. Specific DNA sequences (motifs) can act as binding sites for specific transcription factors and combinations of these transcription factors help recruit RNA pol II to the promoter. ...
Your question refers to differential gene expression and methods of Eukaryotic gene regulation. This is a very broad question for there are a lot of methods to control gene expression. They can function as transcription control, mRNA processing control, translational control, post-translational control and so on in eukaryotes. In prokaryotes, the methods ...
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