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From Uptodate on Clinical Manifestations of Hypocalcemia: Acute hypocalcemia directly increases peripheral neuromuscular irritability [ 1 ]. As measured electromyographically, tetany consists of repetitive high-frequency discharges after a single stimulus. Hyperexcitability of peripheral neurons is probably the most important pathophysiologic effect of ...


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Without answering the problem for you, because you have not shown work yet to try to figure out which is which, let me tell you that you have three options. Skeletal Muscle- striated, peripherally located nuclei, same thickness along length, non-branching Cardiac Muscle- striated, few centrally located nuclei, branches and anastamosis Smooth Muscle- ...


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It is a question of transmembrane potential. Ca++ being a cation, means that if you decrease the amount of ionized calcium in the extra cellular fluid, it conceptually is nearly equivalent to having a more positively charged intracellular fluid. This in turn means that the cell will be closer to its threshold potential for depolarization, therefore ...


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The tendon is the part of the muscle that connects directly to the bone. A tendon (or sinew) is a tough band of fibrous connective tissue that usually connects muscle to bone and is capable of withstanding tension. Tendons are similar to ligaments and fasciae; all three are made of collagen. Ligaments join one bone to another bone; fasciae connect ...


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In the case of myofibrils this is the case because of the syncytial nature of that given structure. It means that in developing muscle tissue after a certain stage the cell divisions become somewhat different in that the final step, being separation of the daughter cells via invagination of cell membranes, does not happen. The nuclei though keep dividing ...



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