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1

There's a decent presentation here that basically goes over what you're asking. As an inhibitor, azides are similar to cyanide in that they inhibit complex IV by binding cytochrome oxidase, resulting in a sort of chemical asphyxiation. Uncouplers are a little harder to wrap your head around. They embed in the membrane space, and we know that ETC and ...


0

From an engineering point of view, if you chew it the surface area will be enlarged. For example, you take 2 containers with water and 2 tablets which will dissolve in this water. If you crumble one tablet, the take up rate (flux) will be much higher due to the enlarged surface area of the tablet. If you add mixing to the concept, the flux will increase even ...


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Aspirin and some other NSAIDs inhibit cyclooxygenase which is the first enzyme in the prostaglandin/thromboxane biosynthesis pathway if you consider first substance is arachidonic acid (a fatty acid). Generally, arachidonic acid is present in the form of a phospholipid, and if you consider that in the pathway, substance-Y is arachidonic acid and enzyme-A is ...



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