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The pattern we see in B. subtilis is quite common in prokaryotes. The origin of replication is shown at the top of the genome diagram. DNA replication proceeds bidirectionally from this point. In the B. subtilis diagram, most genes are located along the leading strand in each direction. Even in E. coli, by the way, important genes, including all rRNAs, tend ...


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Though Escherichia coli has only one origin of replication (oriC), keep in mind that replication proceeds in both directions from it. Thus, based on your calculations, DNA replication takes 40 minutes (which is still too long). The solution is to start replication again before the previous round has completed, and here's some research which shows just that: ...



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