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From the statistical point of view, this question is rather vague. One would need a mathematical definition for the term "genetic variance". In one extreme, if the "genetic variance" merely means the categorial variations of nucleotides (i.e. ACTG) in the pooled genomes of interest, then the distribution of total "genetic variance" vs. loci variation is ...


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LD describes the associations among alleles at different loci. For anything more than two bi-allelic loci, you need more than just one number to fully describe the associations. For instance, if we have three bi-allelic loci 1-3, we need the three pairwise LD coefficients, plus one extra three-way coefficient. In general, if we have $K$ loci, and the ...


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Being a typical molecular biologist, I am a little uncomfortable with classical genetics terms. I might redefine some symbols (perhaps to mean the same) [It is like talking to oneself while thinking]. There are four DNA-blocks : A1, B1, A2 and B2. Ak and Bk are adjacent blocks. [Perhaps this is same as what you defined the symbols as]. A and B are ...


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There are so many things that are implied in this paper, not explicitly said. The mutation rate here detected seems to be the emergence of chain-terminating (CT) mutations, which truncate protein coding genes, usually just one gene in a bacterium or phage, which would be possible to observe from inspecting a plate to see which colonies die or survive. ...



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