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Prions are misfolded proteins with abnormal tertiary or quaternary structures. That grants them resistance (to some extent, at least) to proteases (1). Also researchers believe that prions are able to replicate (2), by changing the structure of other proteins. Regarding the gastrointestinal barrier, that isn't exactly true. It has been shown that small ...


Dr Yong in the paper titled Prion, The unconventional slow Infectious agent states that the formation of amyloid plaque which is a major contributor to Alzheimer's disease is a unconventionally slow infectious disease (Prion). Some papers have also pointed out the similarities between Alzheimers and prion disorders (reference) Cerebral amyloid plaques have ...

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