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The reduced iron availability affects the red cell size during differentiation. The presence of red cells with reduced mean corpuscular volume (MCV) reflects reduced hemoglobin synthesis, which can have several causes. It can result from defects either in iron acquisition or availability, or in heme or globin synthesis. Experimental data in mouse ...


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The problem is partly the definition of Antigen that you quote. It refers to “the body” leading you to assume it’s a specific body — yours. I'm sure there are better definitions, but just taking this one, I would modify to: “A substance that can be recognised as foreign and evoke an immune response in an organism.” With this definition, which is actually ...


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The hematopoietic stem cells are quite rare, and each progenitor cell produced by a stem cell gives rise to a large number of red blood cells (and other blood cell types). I'm not sure if the precise number of offspring for the earliest progenitor cells is known in vivo, but recent cell culture models indicate that early progenitors can give rise to as many ...


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Camel RBCs are anucleate [1, 2]. The dark structure seen in microscopic images is not nuclei but a network of microtubules called the marginal bands. Marginal bands cause these RBCs to adopt an ellipsoid shape. The unique shape of these RBCs possibly allows them to survive osmotic stress and is probably advantageous to a camel under extreme dehydration. ...


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Blood group systems occur where there are multiple alleles of a gene which produces polymorphism in a surface component of the erythrocyte such that the different forms of the component display different antigenicities. This can cause haemolysis of transfused blood that has a different antigenicity to that of the erythrocytes of the recipient, whose immune ...



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