New answers tagged replication
I would assume that the labeling occurs in the reduction of NTPs to form dNTPS. This process (catalyzed by ribonucleotide reductase) involves protonating the hydroxyl group on the 2' carbon, allowing it to leave as water, and then adding a hydride to the newly formed carbocation. The two hydrogen atoms (the proton and the hydride) come from two thiols on ...
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