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It is right that RNA has small areas of complementary base pairing. You asked whether these parts are double helical. DNA has various types of double-helical conformations. Most popular among them is the B-form, A-form and Z-form. The Watson Crick model is similar to the B-form of DNA. It is right-handed double-helical structure. A-form and Z-form are ...


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Formaldehyde forms adducts with RNA and can also make it more susceptible to degradation. It can also cause crosslinks to form between RNA and proteins (or possibly other RNAs). For all these reasons extraction of high quality RNA from formaldehyde fixed samples is very difficult and the yields are low (Howat and Wilson, 2014). Have a look at this article ...



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